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Query: IDE

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
IDE 0 0.512 -0.890 1.510 -1.202

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
IDE Ubiquitylation K308 -0.121 0.325 _IVPIK(gl)DIR_

Background Information for IDE:


Pubmed-IDE »
Uniprot-IDE »
Biogrid-IDE »
ProteomicsDB-IDE »

Tumorportal-IDE »
COSMIC-IDE »
GenomeRNAi-IDE »
Genecards-IDE


Protein-protein Interactions for IDE
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait NES Cat. description Hein, Mann, Cell 2015
Category members IP bait ARSG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C11orf66 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCL23 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CTAGE5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DEFB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DKK4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DOHH Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EGFL6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM19A3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HLA-DPB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HOXC9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HYLS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LEPREL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LIME1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PHF7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPGR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPINK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPINK7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TINAG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSSC4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VIM Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VWCE Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in IDE
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Peptidase_M16_C IPR007863 0.28
Category members Metalloenz_LuxS/M16 IPR011249 0.28
Category members Pept_M16_N IPR011765 0.28


Protein complexes (CORUM database) featuring IDE
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring IDE
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005615 extracellular space Database 4.72
Category members GO Category GO:0016887 ATPase activity Database 2.28
Category members GO Category GO:0006200 ATP catabolic process Database 2.13
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0043130 ubiquitin binding Database 1.22
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0051289 protein homotetramerization Database 0.44
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0010992 ubiquitin homeostasis Database 0.28
Category members GO Category GO:0031597 cytosolic proteasome complex Database 0.23
Category members GO Category GO:0005782 peroxisomal matrix Database 0.23
Category members GO Category GO:0008286 insulin receptor signaling pathway Database 0.2
Category members GO Category GO:0009986 cell surface Database 0.17
Category members GO Category GO:0010815 bradykinin catabolic process Database 0.11
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0008340 determination of adult lifespan Database 0.05
Category members GO Category GO:0042447 hormone catabolic process Database 0.05
Category members GO Category GO:0043559 insulin binding Database 0.04
Category members Pathway Pathway_29 KEGG_ALZHEIMERS_DISEASE 0 0
Category members GO Category GO:0001540 beta-amyloid binding Database 0
Category members GO Category GO:0001948 glycoprotein binding Database 0
Category members GO Category GO:0004222 metalloendopeptidase activity Database 0
Category members GO Category GO:0005102 receptor binding Database 0
Category members GO Category GO:0005777 peroxisome Database 0
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0017046 peptide hormone binding Database 0
Category members GO Category GO:0032461 positive regulation of protein oligomerization Database 0
Category members GO Category GO:0042277 peptide binding Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0044257 cellular protein catabolic process Database 0
Category members GO Category GO:0045861 negative regulation of proteolysis Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0050435 beta-amyloid metabolic process Database 0
Category members GO Category GO:0051260 protein homooligomerization Database 0
Category members GO Category GO:0051291 protein heterooligomerization Database 0
Category members GO Category GO:0051603 proteolysis involved in cellular protein catabolic process Database 0


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