RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
MSH6	2	-0.410	0.140	-0.115	0.232	0.645	0.407	0.101
MSH2	1	-0.130	0.010	0.224	0.457	0.838	0.840	0.366
HTT	1	-0.200	-0.360	0.632			0.847	0.550
TFCP2L1	0	-1.120	0.880	0.684	0.006	0.158	1.331	0.870
IDE	0	-0.890	1.510					-1.202
TP53	0	-1.070	1.050	-2.808	0.076	-0.094	0.436	0.497
LRRK2	0	0.530	-0.620	-0.240

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
HTT	Ubiquitylation	K260		-0.128	_AFIANLK(gl)_
HTT	Phosphorylation	S419	0.595	0.531	_SGS(ph)IVELIAGGGSSCS(ph)PVLSR_
HTT	Phosphorylation	S430	0.402	0.494	_SGSIVELIAGGGSS(ph)CSPVLSR_
HTT	Phosphorylation	S432	0.317	0.640	_SGSIVELIAGGGSSCS(ph)PVLSR_
HTT	Phosphorylation	S1195	-0.222	0.264	_EKEPGEQAS(ph)VPLSPK_
HTT	Phosphorylation	S1199	-0.456	-0.970	_GKEKEPGEQASVPLS(ph)PK_
HTT	Ubiquitylation	K1402	0.169	-0.538	_VSTQLK(gl)TNLTSVTK_
HTT	Phosphorylation	S1874	1.994	1.028	_LLSPQMS(ph)GEEEDSDLAAK_
IDE	Ubiquitylation	K308	-0.121	0.325	_IVPIK(gl)DIR_
MSH2	Ubiquitylation	K212		-0.233	_ECVLPGGETAGDMGK(gl)LR_
MSH2	Ubiquitylation	K249	0.461		_K(gl)GEQMNSAVLPEMENQVAVSSLSAVIK_
MSH2	Ubiquitylation	K347		2.867	_LVNQWIK(gl)QPLMDK_
MSH2	Ubiquitylation	K531	1.040		_VTCKEEK(gl)VLR_
MSH2	Ubiquitylation	K555		0.164	_FTNSK(gl)LTSLNEEYTK_
MSH2	Ubiquitylation	K635		-0.376	_IILK(gl)ASR_
MSH6	Phosphorylation	S41	-0.708	-0.948	_AAAAPGAS(ph)PSPGGDAAWSEAGPGPRPLAR_
MSH6	Phosphorylation	S43	0.319	-0.234	_AAAAPGASPS(ph)PGGDAAWSEAGPGPR_
MSH6	Phosphorylation	S137	0.203	0.359	_VHVQFFDDS(ph)PTR_
MSH6	Phosphorylation	T139	0.209		_VHVQFFDDSPT(ph)R_
MSH6	Phosphorylation	S227	-0.199	-0.192	_SEEDNEIES(ph)EEEVQPK_
MSH6	Ubiquitylation	K334		0.193	_QATSISSETK(gl)NTLR_
MSH6	Ubiquitylation	K476	1.536	0.184	_YSDSLVQK(gl)GYK_
MSH6	Ubiquitylation	K519	2.264	0.186	_IITK(gl)GTQTYSVLEGDPSENYSK_
MSH6	Ubiquitylation	K728	0.082	-0.280	_SGAIFTK(gl)AYQR_
MSH6	Ubiquitylation	K771	-0.582	-1.069	_VDTCHTPFGK(gl)R_
MSH6	Phosphorylation	S830	0.130	1.666	_IHNVGS(ph)PLK_
MSH6	Ubiquitylation	K852		-0.044	_AIMYEETTYSK(gl)K_
MSH6	Ubiquitylation	K853		-0.044	_AIMYEETTYSK(gl)K_
MSH6	Ubiquitylation	K896		-0.342	_QVISLQTK(gl)NPEGR_
MSH6	Ubiquitylation	K997		-0.863	_NLPEEYELK(gl)STK_
MSH6	Ubiquitylation	K1009		-0.817	_YWTK(gl)TIEK_
MSH6	Ubiquitylation	K1030	0.394	-0.156	_DVSLK(gl)DCMR_
MSH6	Ubiquitylation	K1240		-0.672	_ELAETIK(gl)CR_
MSH6	Ubiquitylation	K1291		0.633	_FIK(gl)GACPK_
MSH6	Ubiquitylation	K1296		-1.142	_GACPK(gl)SYGFNAAR_
MSH6	Ubiquitylation	K1315		-1.738	_LANLPEEVIQK(gl)GHR_
MSH6	Ubiquitylation	K1325		-0.190	_EFEK(gl)MNQSLR_
TP53	Ubiquitylation	K120	-0.188		_LGFLHSGTAK(gl)SVTCTYSPALNK_
TP53	Ubiquitylation	K164	0.157	-1.260	_AMAIYK(gl)QSQHMTEVVR_
TP53	Phosphorylation	S314	-0.695	-1.000	_ALPNNTSS(ph)SPQPK_
TP53	Phosphorylation	S315	-0.762	-0.959	_RALPNNTSSS(ph)PQPK_
TP53	Ubiquitylation	K320	-0.978		_ALPNNTSSSPQPKK(gl)_
TP53	Ubiquitylation	K357	-0.231	-0.823	_ELNEALELKDAQAGK(gl)EPGGSR_