RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
W

Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
ITPR3	2	-0.190	-0.500				1.489	1.835
MED24	1	-1.120	1.330	-0.351	-0.190	0.792		-0.333
CTNNA1	1	-0.520	1.660		-0.690	-1.164
CTNNA1	1	-0.520	1.660	0.139			0.436	0.323
CASP8	1	1.120	-1.090
TSC2	1	0.810	-0.710
TSC2	1	0.810	-0.710	-0.715
TRAF2	1	-0.570	0.540
TRAF2	1	-0.570	0.540
PRKCSH	1	0.550	0.060				0.459	0.419
IGF1R	1	-0.490	0.750				1.476	0.714
ILK	1	-1.560	3.680				-0.463	-0.527
MAP2K1	1	-1.590	2.780
PPP5C	0	-0.140	-0.230	0.937
PPP5C	0	-0.140	-0.230
TNFRSF1A	0	-0.590	0.470
PRKCZ	0	-0.290	0.310
BIRC2	0	-0.730	0.440
BIRC2	0	-0.730	0.440
PRKAB1	0	0.640	-1.180
STXBP3	0	1.010	-0.860	-0.522			0.293	0.257
STK11	0
IDE	0	-0.890	1.510					-1.202
SEPT7	0
PRKAA1	0	0.910	0.060
CAB39	0	-0.920	0.670
RIPK1	0	-0.190	0.440
SEPT11	0	-0.730	0.500				0.809	0.014
SEPT11	0	-0.730	0.500
BRAF	0
SQSTM1	0	-0.860	1.770	-2.165			-2.063	-1.741
SQSTM1	0	-0.440	0.530	-2.165			-2.063	-1.741
TSC1	0	1.100	-0.150
YWHAB	0				0.628	-0.543
YWHAB	0			0.507			0.271	0.503
CTNNB1	0	0.490	-0.230
CTNNB1	0	0.490	-0.230	-0.415			0.628	0.215
UQCRH	0
HRAS	0	1.470	-0.520
GRB2	0	-0.240	0.300		-1.021	0.057	0.906
PRKAG1	0	0.400	-0.420	0.278			-0.667
HBA1	0	0.650	-0.920
HBA1	0	1.470	-0.850

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
BIRC2	Ubiquitylation	K15	-0.259	0.307	_(ac)MEDSTILSDWTNSNK(gl)QK_
BIRC2	Ubiquitylation	K17	-0.259	0.307	_(ac)MEDSTILSDWTNSNK(gl)QK_
BIRC2	Ubiquitylation	K38	-0.069		_SIMEDSTILSDWTNSNKQK(gl)_
BIRC2	Ubiquitylation	K102		-1.755	_LGDSPIQK(gl)HK_
BIRC2	Ubiquitylation	K233	-0.511		_LSNWEPK(gl)DDAMSEHR_
BIRC2	Ubiquitylation	K410		0.878	_DLVK(gl)QTVQSK_
BIRC2	Ubiquitylation	K490	0.305	0.534	_ANVINK(gl)QEHDIIK_
BIRC2	Ubiquitylation	K497	-1.934		_ANVINKQEHDIIK(gl)QK_
BRAF	Phosphorylation	S151	-0.685	-0.629	_SNPKS(ph)PQKPIVR_
BRAF	Phosphorylation	S363	-0.023	-0.241	_S(ph)SSAPNVHINTIEPVNIDDLIR_
BRAF	Phosphorylation	S365	-0.286	0.012	_SSS(ph)APNVHINTIEPVNIDDLIR_
BRAF	Phosphorylation	S399	-0.890	-0.527	_GDGGSTTGLS(ph)ATPPASLPGSLTNVK_
BRAF	Phosphorylation	T401	-0.525		_GDGGSTTGLSAT(ph)PPASLPGSLTNVK_
BRAF	Phosphorylation	S446	0.246	0.349	_RDS(ph)SDDWEIPDGQITVGQR_
BRAF	Phosphorylation	S447	0.579	0.623	_RDSS(ph)DDWEIPDGQITVGQR_
BRAF	Phosphorylation	S729	0.208	0.219	_SAS(ph)EPSLNR_
CAB39	Ubiquitylation	K20	0.992		_NLK(gl)ESMAVLEK_
CASP8	Ubiquitylation	K183	1.917		_IINDYEEFSK(gl)ER_
CASP8	Ubiquitylation	K461		-2.031	_NMGK(gl)QMPQPTFTLR_
CTNNA1	Ubiquitylation	K16	-0.194	-0.141	_WDPK(gl)SLEIR_
CTNNA1	Ubiquitylation	K45	-1.131	-0.728	_LLEPLVTQVTTLVNTNSK(gl)GPSNK_
CTNNA1	Ubiquitylation	K120		-0.333	_AAAGEFADDPCSSVK(gl)R_
CTNNA1	Ubiquitylation	K414	0.977		_NGNEK(gl)EVKEYAQVFR_
CTNNA1	Ubiquitylation	K417	0.211		_NGNEK(gl)EVKEYAQVFR_
CTNNA1	Phosphorylation	S641	-0.056	0.089	_TPEELDDS(ph)DFETEDFDVR_
CTNNA1	Phosphorylation	T654	0.808	0.392	_SRT(ph)SVQTEDDQLIAGQSAR_
CTNNA1	Phosphorylation	S655	1.043	0.882	_SRTS(ph)VQTEDDQLIAGQSAR_
CTNNA1	Ubiquitylation	K683	3.760	-0.837	_AIMAQLPQEQKAK(gl)_
CTNNA1	Ubiquitylation	K747		-0.384	_NTSDVISAAK(gl)K_
CTNNA1	Ubiquitylation	K748	-0.083	-0.384	_NTSDVISAAKK(gl)_
CTNNB1	Ubiquitylation	K158		-1.265	_AIPELTK(gl)LLNDEDQVVVNK_
CTNNB1	Ubiquitylation	K180	-0.546	-0.636	_AAVM(ox)VHQLSK(gl)K_
CTNNB1	Ubiquitylation	K181	-0.717	-0.729	_AAVMVHQLSKK(gl)_
CTNNB1	Phosphorylation	S191	-0.024	0.129	_S(ph)PQMVSAIVR_
CTNNB1	Ubiquitylation	K435		-0.350	_NK(gl)MM(ox)VCQVGGIEALVR_
CTNNB1	Ubiquitylation	K496		-1.262	_LHYGLPVVVK(gl)_
CTNNB1	Phosphorylation	S552	1.233	1.224	_RTS(ph)MGGTQQQFVEGVR_
CTNNB1	Phosphorylation	T556	1.275	0.995	_RTSM(ox)GGT(ph)QQQFVEGVR_
CTNNB1	Ubiquitylation	K671	-0.941	-0.934	_MSEDKPQDYK(gl)K_
GRB2	Ubiquitylation	K10	0.146		_YDFK(gl)ATADDELSFK_
GRB2	Ubiquitylation	K20	-0.078		_ATADDELSFK(gl)R_
GRB2	Ubiquitylation	K69	-0.362	0.641	_AK(gl)AEEMLSK_
GRB2	Ubiquitylation	K76	0.754		_AEEMLSK(gl)QR_
GRB2	Ubiquitylation	K109	0.381	-0.002	_FGNDVQHFK(gl)VLR_
HRAS	Ubiquitylation	K170	-1.005		_K(gl)LNPPDESGPGCMSCK_
IDE	Ubiquitylation	K308	-0.121	0.325	_IVPIK(gl)DIR_
IGF1R	Ubiquitylation	K47		1.146	_NDYQQLK(gl)R_
IGF1R	Ubiquitylation	K1033	5.779		_VAIK(gl)TVNEAASMR_
IGF1R	Ubiquitylation	K1168	0.191		_K(gl)GGKGLLPVR_
IGF1R	Ubiquitylation	K1171	0.232		_GGK(gl)GLLPVR_
ILK	Ubiquitylation	K85		-0.777	_DIVQK(gl)LLQYK_
ILK	Ubiquitylation	K426		-0.300	_LMK(gl)ICMNEDPAK_
ILK	Ubiquitylation	K435		-2.732	_ICMNEDPAK(gl)RPK_
ITPR3	Ubiquitylation	K529	1.377		_EK(gl)GGEGPLVR_
ITPR3	Phosphorylation	S934	0.318	-0.802	_KQS(ph)VFSAPSLSAGASAAEPLDR_
ITPR3	Phosphorylation	S937		-0.026	_KQSVFS(ph)APSLSAGASAAEPLDR_
ITPR3	Ubiquitylation	K1534		-0.220	_TLAMVAK(gl)GR_
ITPR3	Phosphorylation	S1832	0.650	0.560	_VAS(ph)FSIPGSSSR_
ITPR3	Ubiquitylation	K2597		-0.819	_NK(gl)NLDWFPR_
ITPR3	Ubiquitylation	K2628		-0.010	_ILQDK(gl)LNSTMK_
ITPR3	Phosphorylation	S2670	1.132	1.555	_LGFVDVQNCIS(ph)R_
MAP2K1	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K1	Phosphorylation	S385		0.066	_RSDAEEVDFAGWLCSTIGLNQPS(ph)TPTHAAGV_
MAP2K1	Phosphorylation	T386		0.377	_RSDAEEVDFAGWLCSTIGLNQPST(ph)PTHAAGV_
MED24	Phosphorylation	S862	1.164	0.238	_LLS(ph)SNEDDANILSS(ph)PTDR_
MED24	Phosphorylation	S863	2.413		_LLSS(ph)NEDDANILSS(ph)PTDR_
MED24	Phosphorylation	S873	0.174	0.861	_LLSSNEDDANILSS(ph)PTDR_
PPP5C	Ubiquitylation	K42	-0.703		_AK(gl)DYENAIK_
PRKAA1	Ubiquitylation	K271		-0.536	_ATIK(gl)DIR_
PRKAA1	Ubiquitylation	K396		-0.419	_HTLDELNPQK(gl)SK_
PRKAA1	Ubiquitylation	K485	-1.326	-1.554	_SIDDEITEAK(gl)SGTATPQR_
PRKAB1	Phosphorylation	S108	-0.357	0.129	_S(ph)HNNFVAILDLPEGEHQYK_
PRKAG1	Ubiquitylation	K78		-0.588	_AAPLWDSK(gl)K_
PRKAG1	Ubiquitylation	K79		-0.588	_AAPLWDSK(gl)K_
PRKAG1	Ubiquitylation	K243	-0.525	-0.505	_VSALPVVDEK(gl)GR_
PRKCSH	Ubiquitylation	K383	1.564	0.883	_NK(gl)FEEAER_
PRKCZ	Phosphorylation	T560	-0.884	-1.578	_KQALPPFQPQITDDYGLDNFDTQFTSEPVQLT(ph)PDDEDAIKR_
RIPK1	Ubiquitylation	K642	-0.431		_EGIK(gl)GATVGK_
SEPT11	Phosphorylation	S9	0.030	0.357	_(ac)AVAVGRPS(ph)NEELR_
SEPT11	Ubiquitylation	K172		-0.228	_SLDLVTMKK(gl)_
SEPT11	Ubiquitylation	K337		0.431	_RNEFLGELQK(gl)_
SEPT7	Ubiquitylation	K88	0.195		_IK(gl)KTVQVEQSK_
SEPT7	Ubiquitylation	K209	0.315	0.490	_ADTLTPEECQQFKK(gl)_
SEPT7	Ubiquitylation	K213	1.008	1.111	_QIMK(gl)EIQEHK_
SEPT7	Ubiquitylation	K219	0.414	0.573	_EIQEHK(gl)IK_
SEPT7	Ubiquitylation	K333		0.134	_GQLTK(gl)SPLAQMEEERR_
SEPT7	Phosphorylation	S334	0.362	0.417	_S(ph)PLAQMEEERR_
SEPT7	Ubiquitylation	K395	0.680		_NLEAQHK(gl)ELEEK_
SEPT7	Phosphorylation	T426		0.290	_ILEQQNSSRT(ph)LEK_
SQSTM1	Ubiquitylation	K13	0.150	0.302	_AYLLGK(gl)EDAAR_
SQSTM1	Phosphorylation	S28		-0.721	_RFSFCCS(ph)PEPEAEAEAAAGPGPCER_
SQSTM1	Ubiquitylation	K141	-0.915		_YK(gl)CSVCPDYDLCSVCEGK_
SQSTM1	Ubiquitylation	K157	-0.852	-0.677	_CSVCPDYDLCSVCEGK(gl)GLHR_
SQSTM1	Phosphorylation	T269	-0.681	-0.421	_LT(ph)PVS(ph)PESSSTEEK_
SQSTM1	Phosphorylation	S272	0.171	0.044	_LTPVS(ph)PESSSTEEK_
SQSTM1	Phosphorylation	S332		-0.007	_IALESEGRPEEQMESDNCS(ph)GGDDDWTHLSSK_
SQSTM1	Ubiquitylation	K420	-1.122	-0.061	_LLQTK(gl)NYDIGAALDTIQYSK_
SQSTM1	Ubiquitylation	K435	-1.352	-0.780	_NYDIGAALDTIQYSK(gl)HPPPL_
STK11	Phosphorylation	S31	0.437	0.073	_IDS(ph)TEVIYQPR_
STK11	Phosphorylation	T32	1.256	0.248	_IDS(ph)TEVIYQPR_
STXBP3	Ubiquitylation	K19		-0.876	_SVVWQKIK(gl)_
STXBP3	Ubiquitylation	K220	0.734		_KLEDYYK(gl)IDEK_
STXBP3	Ubiquitylation	K224	0.370	0.367	_IDEK(gl)SLIK_
STXBP3	Ubiquitylation	K321	0.844	0.698	_ATEGK(gl)TSLSALTQLMK_
STXBP3	Ubiquitylation	K332	1.105		_TSLSALTQLMK(gl)K_
STXBP3	Ubiquitylation	K333		0.016	_TSLSALTQLMKK(gl)_
STXBP3	Ubiquitylation	K359	-0.603		_FK(gl)LNIEK_
STXBP3	Ubiquitylation	K364		-0.235	_LNIEK(gl)LCK_
STXBP3	Ubiquitylation	K367	0.264	0.382	_LCK(gl)TEQDLALGTDAEGQK_
STXBP3	Ubiquitylation	K384	0.874		_TEQDLALGTDAEGQKVK(gl)DSMR_
STXBP3	Ubiquitylation	K585	1.271		_DK(gl)VSLIKDE_
TNFRSF1A	Ubiquitylation	K242		-0.111	_SK(gl)LYSIVCGK_
TRAF2	Phosphorylation	T7	-0.822	-1.190	_(ac)AAASVT(ph)PPGSLELLQPGFSK_
TRAF2	Ubiquitylation	K27	-0.253	2.194	_TLLGTK(gl)LEAK_
TRAF2	Ubiquitylation	K119		0.519	_GTLK(gl)EYESCHEGR_
TRAF2	Ubiquitylation	K176	-1.233	1.022	_APCCGADVK(gl)AHHEVCPK_
TRAF2	Ubiquitylation	K207	0.147	0.918	_FQDHVK(gl)TCGK_
TRAF2	Ubiquitylation	K481	-0.507	0.417	_MEAK(gl)NSYVR_
TSC1	Phosphorylation	S505	0.141	0.350	_GGFDS(ph)PFYR_
TSC2	Ubiquitylation	K3		-1.397	_(ac)AK(gl)PTSKDSGLK_
TSC2	Ubiquitylation	K14		-1.297	_DSGLKEK(gl)FK_
TSC2	Ubiquitylation	K69		0.051	_MIGQICEVAK(gl)TK_
TSC2	Ubiquitylation	K71		-0.157	_MIGQICEVAKTK(gl)_
TSC2	Ubiquitylation	K258		-0.278	_ELCEPCWK(gl)LMR_
TSC2	Ubiquitylation	K634		1.610	_LGLPNK(gl)DGVVR_
TSC2	Phosphorylation	S950	-0.152	-0.529	_STS(ph)LNERPK_
TSC2	Phosphorylation	S1064		-0.927	_SLLGLDSGELQSGPESSSS(ph)PGVHVR_
TSC2	Phosphorylation	S1248		-0.604	_SNTDSAVVMEEGS(ph)PGEVPVLVEPPGLEDVEAALGMDRR_
TSC2	Phosphorylation	S1329	-0.120		_S(ph)SSSPELQTLQDILGDPGDK_
TSC2	Phosphorylation	S1331	-0.262		_SSS(ph)SPELQTLQDILGDPGDKADVGR_
TSC2	Phosphorylation	S1332		-0.063	_SSSS(ph)PELQTLQDILGDPGDK_
TSC2	Phosphorylation	S1355	0.174	0.351	_ADVGRLS(ph)PEVK_
TSC2	Phosphorylation	S1362		0.859	_S(ph)QSGTLDGESAAWSASGEDSR_
TSC2	Phosphorylation	S1364	0.522	0.550	_SQS(ph)GTLDGESAAWSASGEDSR_
TSC2	Phosphorylation	T1366	0.137		_SQSGT(ph)LDGESAAWSASGEDSR_
TSC2	Phosphorylation	S1396		0.498	_S(ph)PSGLRPR_
TSC2	Phosphorylation	S1743	0.596		_RLISS(ph)VEDFTEFV_
UQCRH	Ubiquitylation	K42	-0.522	1.440	_EQCEQLEK(gl)CVK_
YWHAB	Ubiquitylation	K11	1.057	1.322	_(ac)TMDKSELVQK(gl)AK_
YWHAB	Ubiquitylation	K13	0.060	0.388	_AK(gl)LAEQAER_
YWHAB	Ubiquitylation	K70	0.558	-0.175	_VISSIEQK(gl)TER_
YWHAB	Ubiquitylation	K140		0.531	_YLSEVASGDNK(gl)QTTVSNSQQAYQEAFEISKK_
YWHAB	Ubiquitylation	K159	0.300		_QTTVSNSQQAYQEAFEISK(gl)K_
YWHAB	Ubiquitylation	K160	-0.439	-0.371	_K(gl)EMQPTHPIR_