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Query: STXBP3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
STXBP3 0 1.997 1.010 -0.860 -0.522 0.293 0.257

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
STXBP3 Ubiquitylation K321 0.844 0.698 _ATEGK(gl)TSLSALTQLMK_
STXBP3 Ubiquitylation K367 0.264 0.382 _LCK(gl)TEQDLALGTDAEGQK_
STXBP3 Ubiquitylation K224 0.370 0.367 _IDEK(gl)SLIK_
STXBP3 Ubiquitylation K333 0.016 _TSLSALTQLMKK(gl)_
STXBP3 Ubiquitylation K364 -0.235 _LNIEK(gl)LCK_
STXBP3 Ubiquitylation K19 -0.876 _SVVWQKIK(gl)_
STXBP3 Ubiquitylation K220 0.734 _KLEDYYK(gl)IDEK_
STXBP3 Ubiquitylation K332 1.105 _TSLSALTQLMK(gl)K_
STXBP3 Ubiquitylation K359 -0.603 _FK(gl)LNIEK_
STXBP3 Ubiquitylation K384 0.874 _TEQDLALGTDAEGQKVK(gl)DSMR_
STXBP3 Ubiquitylation K585 1.271 _DK(gl)VSLIKDE_

Background Information for STXBP3:


Pubmed-STXBP3 »
Uniprot-STXBP3 »
Biogrid-STXBP3 »
ProteomicsDB-STXBP3 »

Tumorportal-STXBP3 »
COSMIC-STXBP3 »
GenomeRNAi-STXBP3 »
Genecards-STXBP3


Protein-protein Interactions for STXBP3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AAGAB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ASPH Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR141 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPRC5B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ICMT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IPPK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPPR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STXBP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM30B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM97 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in STXBP3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Sec1-like IPR001619 1.02


Protein complexes (CORUM database) featuring STXBP3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring STXBP3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members GO Category GO:0043312 neutrophil degranulation Database 0.62
Category members GO Category GO:0006904 vesicle docking involved in exocytosis Database 0.51
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0030168 platelet activation Database 0.13
Category members Pathway Pathway_56 REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION 0 0.11
Category members GO Category GO:0017075 syntaxin-1 binding Database 0.09
Category members GO Category GO:0019905 syntaxin binding Database 0.05
Category members GO Category GO:0070527 platelet aggregation Database 0.05
Category members GO Category GO:0016323 basolateral plasma membrane Database 0.04
Category members GO Category GO:0070820 tertiary granule Database 0.03
Category members Pathway Pathway_55 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ 0 0
Category members GO Category GO:0016324 apical plasma membrane Database 0
Category members GO Category GO:0031091 platelet alpha granule Database 0
Category members GO Category GO:0042581 specific granule Database 0
Category members GO Category GO:0045955 negative regulation of calcium ion-dependent exocytosis Database 0
Category members GO Category GO:0051291 protein heterooligomerization Database 0


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