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Query: PPP5C

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PPP5C 0 0.234 -0.140 -0.230
PPP5C 0 0.234 -0.140 -0.230 0.937

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PPP5C Ubiquitylation K42 -0.703 _AK(gl)DYENAIK_

Background Information for PPP5C:


Pubmed-PPP5C »
Uniprot-PPP5C »
Biogrid-PPP5C »
ProteomicsDB-PPP5C »

Tumorportal-PPP5C »
COSMIC-PPP5C »
GenomeRNAi-PPP5C »
Genecards-PPP5C


Protein-protein Interactions for PPP5C
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PPP5C Cat. description Hein, Mann, Cell 2015
Category members IP bait BPHL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POLD2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PPP5C
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TPR_1 IPR001440 1.39
Category members TPR-contain_dom IPR013026 0.97
Category members TPR_repeat IPR019734 0.93
Category members Ser/Thr-sp_prot-phosphatase IPR006186 0.88
Category members TPR_2 IPR013105 0.45
Category members Calcineurin-like_PHP_apaH IPR004843 0.24
Category members Metallo-depent_PP-like IPR029052 0.23
Category members PPP_dom IPR013235 0


Protein complexes (CORUM database) featuring PPP5C
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PPP5C
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0007067 mitosis Database 2.23
Category members Pathway Pathway_579 PID_ERBB1_DOWNSTREAM_PATHWAY 0 1.97
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_45 PID_REG_GR_PATHWAY 0 0.31
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0016787 hydrolase activity Database 0.22
Category members GO Category GO:0004722 protein serine/threonine phosphatase activity Database 0.11
Category members GO Category GO:0004721 phosphoprotein phosphatase activity Database 0.11
Category members GO Category GO:0008219 cell death Database 0.08
Category members GO Category GO:0043005 neuron projection Database 0.08
Category members Pathway Pathway_715 KEGG_MAPK_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0004871 signal transducer activity Database 0
Category members GO Category GO:0006470 protein dephosphorylation Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0008289 lipid binding Database 0
Category members GO Category GO:0043025 neuronal cell body Database 0
Category members GO Category GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling Database 0
Category members GO Category GO:0043278 response to morphine Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0051291 protein heterooligomerization Database 0


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