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Query: NRD1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NRD1 0 2.132 0.850 -0.580

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NRD1 Phosphorylation S94 0.185 0.340 _RGS(ph)LSNAGDPEIVK_
NRD1 Phosphorylation S86 0.650 _LGADES(ph)EEEGRRGSLSNAGDPEIVK_
NRD1 Phosphorylation S96 0.250 _LGADESEEEGRRGSLS(ph)NAGDPEIVK_
NRD1 Ubiquitylation K352 1.142 _YFK(gl)EALDR_
NRD1 Ubiquitylation K1061 1.043 _YNSEVVDK(gl)K_
NRD1 Ubiquitylation K1062 0.828 _YNSEVVDKK(gl)_

Background Information for NRD1:


Pubmed-NRD1 »
Uniprot-NRD1 »
Biogrid-NRD1 »
ProteomicsDB-NRD1 »

Tumorportal-NRD1 »
COSMIC-NRD1 »
GenomeRNAi-NRD1 »
Genecards-NRD1


Protein-protein Interactions for NRD1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATM Cat. description Hein, Mann, Cell 2015
Category members IP bait ERP44 Cat. description Hein, Mann, Cell 2015
Category members IP bait FUS Cat. description Hein, Mann, Cell 2015
Category members IP bait HAUS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF7 Cat. description Hein, Mann, Cell 2015
Category members IP bait LGALS3BP Cat. description Hein, Mann, Cell 2015
Category members IP bait MTX2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PCDHB15 Cat. description Hein, Mann, Cell 2015
Category members IP bait PDGFRA Cat. description Hein, Mann, Cell 2015
Category members IP bait SMCHD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait 1-Sep Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AURKAIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BATF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C12orf26 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDRT15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DEF8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FMR1NB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LUC7L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM184A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF707 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NRD1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Peptidase_M16_C IPR007863 0.28
Category members Metalloenz_LuxS/M16 IPR011249 0.28
Category members Pept_M16_N IPR011765 0.28


Protein complexes (CORUM database) featuring NRD1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NRD1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0009986 cell surface Database 0.17
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0004222 metalloendopeptidase activity Database 0
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0007528 neuromuscular junction development Database 0
Category members GO Category GO:0016477 cell migration Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0048408 epidermal growth factor binding Database 0
Category members GO Category GO:0051044 positive regulation of membrane protein ectodomain proteolysis Database 0
Category members GO Category GO:0052548 regulation of endopeptidase activity Database 0


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