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integrin-mediated signaling pathway
(GO:0007229)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
CUL3 2 2.600 -1.300 0.182 -0.454 0.077 -0.259 -0.135
FERMT2 1 0.290 -0.340 1.597
MYH9 1 -1.530 2.620 0.366 -0.040 -0.375 0.136 -0.183
DST 1 0.080 -0.480
DST 1 0.080 -0.480 0.991 1.748
DST 1 0.080 -0.480 0.105 -0.034 0.278
DST 1 0.080 -0.480 0.796 0.236
ILK 1 -1.560 3.680 -0.463 -0.527
NME2 0 0.040 0.180 -0.783 0.303 -0.394 -0.805 -0.898
PXN 0 1.020 -0.760
ITGA6 0 -0.530 0.420 -0.133 -0.561 -0.048
ERBB2IP 0 0.430 0.290 -0.247 -0.786 -0.105
ITGB6 0 -0.450 0.870 1.047 0.718
ITGA4 0 -0.620 0.820
LAMA5 0 -1.280 1.860 1.257 0.402 0.337
ADAM10 0 1.400 -1.040 -0.111 0.009
ITGAV 0 -0.297 -0.090 0.262
ITGB1 0 0.390 -0.650 0.101 -0.036
ADAMTS1 0 -0.440 0.580 -0.624
ITGA5 0 0.320 -0.520 0.858 0.617
ITGA2 0 -0.370 0.660 0.847 0.435
ADAM9 0 0.290 -0.290
PRKD1 0 1.050 0.130
PRKD1 0 1.050 0.130
PRKD1 0 1.050 0.130
CD47 0 0.860 -0.750 0.968 0.864
ITGA1 0 -0.750 1.480 0.650 0.069

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ADAM10 Ubiquitylation K721 -2.406 _LPPPKPLPGTLK(gl)R_
ADAM9 Ubiquitylation K741 0.269 0.229 _SQTYESDGK(gl)NQANPSRQPGSVPR_
ADAM9 Phosphorylation S758 -0.375 -0.893 _HVS(ph)PVTPPR_
ADAM9 Phosphorylation T761 -0.724 -0.397 _HVSPVT(ph)PPREVPIYANR_
ADAM9 Ubiquitylation K781 -2.213 _FAVPTYAAK(gl)QPQQFPSRPPPPQPK_
CD47 Ubiquitylation K317 0.065 _AVEEPLNAFKESK(gl)_
CUL3 Ubiquitylation K6 -0.611 _(ac)SNLSK(gl)GTGSR_
CUL3 Ubiquitylation K236 1.952 0.663 _FLAENSASVYIKK(gl)_
CUL3 Ubiquitylation K262 -0.525 -0.203 _STEEPIVK(gl)VVER_
CUL3 Ubiquitylation K292 1.094 0.852 _NGK(gl)TEDLGCMYK_
CUL3 Ubiquitylation K459 0.752 _LK(gl)TECGCQFTSK_
CUL3 Ubiquitylation K680 -1.024 _IQTVAAK(gl)QGESDPERK_
DST Phosphorylation S1382 0.207 1.088 _AMVDSQQKS(ph)PVK_
DST Phosphorylation S7512 0.381 _RGS(ph)DASDFDISEIQSVCSDVETVPQTHRPTPR_
ERBB2IP Phosphorylation S1133 -0.960 _TYS(ph)IDGPNASRPQSARPSINEIPER_
FERMT2 Phosphorylation S159 -0.331 -0.390 _KLDDQS(ph)EDEALELEGPLITPGSGSIYSSPGLYSK_
ILK Ubiquitylation K85 -0.777 _DIVQK(gl)LLQYK_
ILK Ubiquitylation K426 -0.300 _LMK(gl)ICMNEDPAK_
ILK Ubiquitylation K435 -2.732 _ICMNEDPAK(gl)RPK_
ITGA4 Phosphorylation S1021 -0.095 1.014 _RDS(ph)WSYINSK_
ITGA5 Phosphorylation S127 0.200 0.067 _LLESSLSS(ph)SEGEEPVEYK_
ITGA5 Phosphorylation S128 -0.087 _LLESSLSSS(ph)EGEEPVEYK_
ITGA6 Ubiquitylation K1116 0.715 _YIDNLEK(gl)K_
ITGA6 Ubiquitylation K1117 1.453 _YIDNLEKK(gl)_
ITGAV Ubiquitylation K233 0.373 _YDPNVYSIK(gl)YNNQLATR_
ITGAV Ubiquitylation K360 0.294 _ASGDFQTTK(gl)LNGFEVFAR_
ITGAV Ubiquitylation K923 0.636 _GK(gl)SAILYVK_
ITGB1 Ubiquitylation K774 0.402 _MNAK(gl)WDTGENPIYK_
ITGB1 Ubiquitylation K784 -0.172 0.350 _WDTGENPIYK(gl)SAVTTVVNPK_
ITGB1 Ubiquitylation K794 0.755 0.604 _SAVTTVVNPK(gl)YEGK_
LAMA5 Ubiquitylation K255 1.313 _EFTK(gl)ATNVR_
MYH9 Ubiquitylation K66 0.545 _VK(gl)VNKDDIQK_
MYH9 Ubiquitylation K403 0.390 0.869 _DYVQK(gl)AQTK_
MYH9 Ubiquitylation K682 -0.508 _AGK(gl)LDPHLVLDQLR_
MYH9 Ubiquitylation K760 0.409 0.964 _IGQSK(gl)VFFR_
MYH9 Ubiquitylation K821 -0.339 _NCAAYLK(gl)LR_
MYH9 Ubiquitylation K856 -1.336 _EEELVK(gl)VR_
MYH9 Ubiquitylation K860 -0.570 0.212 _VREK(gl)QLAAENR_
MYH9 Ubiquitylation K1274 0.036 _VRTELADK(gl)VTK_
MYH9 Ubiquitylation K1277 0.081 _TELADKVTK(gl)_
MYH9 Ubiquitylation K1413 0.288 _VAAYDKLEK(gl)TK_
MYH9 Ubiquitylation K1415 0.790 _VAAYDKLEKTK(gl)_
MYH9 Phosphorylation S1943 0.168 0.290 _KGAGDGS(ph)DEEVDGKADGAEAK_
NME2 Ubiquitylation K37 0.192 0.188 _TFIAIK(gl)PDGVQR_
NME2 Ubiquitylation K51 -0.368 0.345 _GLVGEIIK(gl)R_
NME2 Ubiquitylation K56 -0.240 _FEQK(gl)GFR_
NME2 Ubiquitylation K125 -0.693 -0.414 _VMLGETNPADSK(gl)PGTIR_
NME2 Ubiquitylation K264 0.448 0.582 _NIIHGSDSVK(gl)SAEK_
PRKD1 Phosphorylation S207 0.941 1.048 _RLS(ph)NVSLTGVSTIR_
PRKD1 Phosphorylation T219 -0.068 -0.162 _T(ph)SSAELSTSAPDEPLLQK_
PRKD1 Phosphorylation S221 -0.662 -0.500 _TSS(ph)AELSTSAPDEPLLQK_
PRKD1 Phosphorylation S225 -0.970 -0.919 _TSSAELSTS(ph)APDEPLLSPVSPGFEQK_
PRKD1 Phosphorylation S236 -0.132 _TSSAELSTSAPDEPLLSPVS(ph)PGFEQK_
PRKD1 Phosphorylation S251 0.474 0.751 _SNS(ph)QSYIGRPIHLDK_
PRKD1 Phosphorylation S399 0.023 0.162 _TIS(ph)PSTSNNIPLMR_
PRKD1 Ubiquitylation K730 1.177 _IIGEK(gl)SFR_
PRKD1 Phosphorylation S744 -0.226 -0.287 _S(ph)VVGTPAYLAPEVLR_
PXN Phosphorylation S85 -0.156 0.192 _FIHQQPQSSS(ph)PVYGSSAK_
PXN Phosphorylation T136 1.322 _SAEPSPTVMST(ph)SLGSNLSELDR_
PXN Phosphorylation S140 -0.291 -0.948 _SAEPSPTVM(ox)STSLGS(ph)NLSELDR_
PXN Phosphorylation S302 -0.167 _S(ph)SPGGQDEGGFMAQGK_
PXN Phosphorylation S303 -0.167 _S(ph)SPGGQDEGGFMAQGK_
PXN Phosphorylation S322 -1.234 _TGSSS(ph)PPGGPPKPGSQLDSMLGSLQSDLNK_


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