bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: ITGA2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ITGA2 0 1.942 -0.370 0.660 0.847 0.435

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for ITGA2:


Pubmed-ITGA2 »
Uniprot-ITGA2 »
Biogrid-ITGA2 »
ProteomicsDB-ITGA2 »

Tumorportal-ITGA2 »
COSMIC-ITGA2 »
GenomeRNAi-ITGA2 »
Genecards-ITGA2


Protein-protein Interactions for ITGA2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANAPC13 Cat. description Hein, Mann, Cell 2015
Category members IP bait C1orf63 Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPH Cat. description Hein, Mann, Cell 2015
Category members IP bait ITGB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAD2L1BP Cat. description Hein, Mann, Cell 2015
Category members IP bait BTNL8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MGAT4C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCGB1D1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SERPINA12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMED6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZACN Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ITGA2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members FG-GAP IPR013517 0.3
Category members Int_alpha_beta-p IPR013519 0.1
Category members Integrin_alpha IPR000413 0.03
Category members Integrin_alpha-2 IPR013649 0.03
Category members VWF_A IPR002035 0


Protein complexes (CORUM database) featuring ITGA2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2429 ITGA2-ITGB1-CD47 complex Database 0.29
Category members Corum 2431 ITGA2-ITGB1-COL6A3 complex Database 0.09
Category members Corum 2432 ITGA2-ITGB1 complex Database 0.09
Category members Corum 2430 ITGA2-ITGB1-CHAD complex Database 0


Categories featuring ITGA2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members Pathway Pathway_645 PID_CXCR4_PATHWAY 0 1.42
Category members Pathway Pathway_309 ST_INTEGRIN_SIGNALING_PATHWAY 0 1.35
Category members Pathway Pathway_1075 REACTOME_L1CAM_INTERACTIONS 0 1.32
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_595 KEGG_FOCAL_ADHESION 0 1.08
Category members Pathway Pathway_673 REACTOME_AXON_GUIDANCE 0 1.06
Category members Pathway Pathway_295 PID_ARF6_TRAFFICKING_PATHWAY 0 0.9
Category members GO Category GO:0001618 virus receptor activity Database 0.83
Category members GO Category GO:0005925 focal adhesion Database 0.68
Category members GO Category GO:0042493 response to drug Database 0.66
Category members GO Category GO:0010694 positive regulation of alkaline phosphatase activity Database 0.65
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0060100 positive regulation of phagocytosis, engulfment Database 0.39
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members Pathway Pathway_449 KEGG_HEMATOPOIETIC_CELL_LINEAGE 0 0.31
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0030198 extracellular matrix organization Database 0.26
Category members GO Category GO:0006928 cellular component movement Database 0.24
Category members GO Category GO:0048661 positive regulation of smooth muscle cell proliferation Database 0.24
Category members GO Category GO:0009612 response to mechanical stimulus Database 0.23
Category members GO Category GO:0030424 axon Database 0.23
Category members GO Category GO:0009986 cell surface Database 0.17
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members GO Category GO:0014075 response to amine Database 0.11
Category members GO Category GO:0045184 establishment of protein localization Database 0.1
Category members GO Category GO:0005178 integrin binding Database 0.09
Category members GO Category GO:0014911 positive regulation of smooth muscle cell migration Database 0.09
Category members Pathway Pathway_580 KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 0 0.08
Category members Pathway Pathway_1022 PID_SYNDECAN_2_PATHWAY 0 0.08
Category members GO Category GO:0010634 positive regulation of epithelial cell migration Database 0.08
Category members GO Category GO:0050729 positive regulation of inflammatory response Database 0.08
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0045785 positive regulation of cell adhesion Database 0.04
Category members GO Category GO:0008305 integrin complex Database 0.03
Category members Pathway Pathway_1007 KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC 0 0.03
Category members GO Category GO:0070365 hepatocyte differentiation Database 0.03
Category members Pathway Pathway_1235 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN 0 0.02
Category members GO Category GO:0005518 collagen binding Database 0.02
Category members GO Category GO:0009897 external side of plasma membrane Database 0
Category members Pathway Pathway_1008 KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM 0 0
Category members Pathway Pathway_1027 PID_INTEGRIN1_PATHWAY 0 0
Category members Pathway Pathway_1286 PID_INTEGRIN_CS_PATHWAY 0 0
Category members Pathway Pathway_24 KEGG_PATHWAYS_IN_CANCER 0 0
Category members Pathway Pathway_262 KEGG_DILATED_CARDIOMYOPATHY 0 0
Category members Pathway Pathway_283 KEGG_SMALL_CELL_LUNG_CANCER 0 0
Category members Pathway Pathway_539 PID_LYMPH_ANGIOGENESIS_PATHWAY 0 0
Category members Pathway Pathway_922 KEGG_ECM_RECEPTOR_INTERACTION 0 0
Category members Pathway Pathway_930 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS 0 0
Category members Disease phenotype Fetal_and_neonatal_alloimmune_thrombocytopenia Fetal and neonatal alloimmune thrombocytopenia Database 0
Category members GO Category GO:0001666 response to hypoxia Database 0
Category members GO Category GO:0001894 tissue homeostasis Database 0
Category members GO Category GO:0002687 positive regulation of leukocyte migration Database 0
Category members GO Category GO:0006971 hypotonic response Database 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0007160 cell-matrix adhesion Database 0
Category members GO Category GO:0007229 integrin-mediated signaling pathway Database 0
Category members GO Category GO:0009279 cell outer membrane Database 0
Category members GO Category GO:0009887 organ morphogenesis Database 0
Category members GO Category GO:0014070 response to organic cyclic compound Database 0
Category members GO Category GO:0014850 response to muscle activity Database 0
Category members GO Category GO:0030879 mammary gland development Database 0
Category members GO Category GO:0031346 positive regulation of cell projection organization Database 0
Category members GO Category GO:0032870 cellular response to hormone stimulus Database 0
Category members GO Category GO:0032967 positive regulation of collagen biosynthetic process Database 0
Category members GO Category GO:0033591 response to L-ascorbic acid Database 0
Category members GO Category GO:0042060 wound healing Database 0
Category members GO Category GO:0042995 cell projection Database 0
Category members GO Category GO:0043236 laminin binding Database 0
Category members GO Category GO:0043388 positive regulation of DNA binding Database 0
Category members GO Category GO:0043589 skin morphogenesis Database 0
Category members GO Category GO:0043679 axon terminus Database 0
Category members GO Category GO:0045178 basal part of cell Database 0
Category members GO Category GO:0045727 positive regulation of translation Database 0
Category members GO Category GO:0045987 positive regulation of smooth muscle contraction Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0050927 positive regulation of positive chemotaxis Database 0
Category members GO Category GO:0050966 detection of mechanical stimulus involved in sensory perception of pain Database 0
Category members GO Category GO:0051971 positive regulation of transmission of nerve impulse Database 0


.

© Copyright Svejstrup Laboratory 2015