Results for the Category
positive regulation of smooth muscle cell proliferation
(GO:0048661)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| JUN | 3 | -0.930 | 0.930 | -0.126 | ||||
| MNAT1 | 0 | -0.030 | -0.100 | 0.666 | ||||
| HMOX1 | 0 | 0.330 | 0.220 | -1.817 | -1.289 | |||
| RPS6KB1 | 0 | 0.850 | -0.600 | |||||
| HMGCR | 0 | 0.240 | 0.010 | |||||
| STAT1 | 0 | -0.550 | 0.170 | |||||
| ID2 | 0 | -0.080 | -0.630 | |||||
| SKP2 | 0 | 0.030 | 0.690 | |||||
| SKP2 | 0 | 0.030 | 0.690 | |||||
| EGFR | 0 | -0.580 | 0.520 | 0.513 | 0.090 | |||
| ITGA2 | 0 | -0.370 | 0.660 | 0.847 | 0.435 | |||
| STAT5B | 0 | 0.670 | -0.960 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| EGFR | Phosphorylation | T693 | 0.486 | -0.139 | _ELVEPLT(ph)PSGEAPNQALLR_ |
| EGFR | Phosphorylation | S991 | -0.041 | _MHLPS(ph)PTDSNFYR_ | |
| HMGCR | Ubiquitylation | K142 | -0.522 | _ASTLAK(gl)FALSSNSQDEVR_ | |
| HMGCR | Ubiquitylation | K248 | -3.854 | -2.107 | _VLEEEENK(gl)PNPVTQR_ |
| HMGCR | Ubiquitylation | K299 | -1.680 | -0.460 | _VSLGLDENVSK(gl)R_ |
| HMGCR | Ubiquitylation | K363 | -1.750 | _NPITSPVVTQKK(gl)_ | |
| HMGCR | Ubiquitylation | K381 | -0.848 | _NNQK(gl)CDSVEEETGINR_ | |
| HMGCR | Ubiquitylation | K401 | -3.050 | _KVEVIK(gl)PLVAETDTPNR_ | |
| HMGCR | Ubiquitylation | K502 | -1.382 | _K(gl)LSEPSSLQYLPYR_ | |
| HMGCR | Ubiquitylation | K633 | -1.104 | _LQK(gl)LHTSIAGR_ | |
| HMGCR | Ubiquitylation | K662 | -1.291 | _SGDAMGMNMISK(gl)GTEK_ | |
| HMGCR | Ubiquitylation | K704 | -1.716 | _GK(gl)SVVCEAVIPAK(gl)VVR_ | |
| HMGCR | Ubiquitylation | K715 | -1.982 | _SVVCEAVIPAK(gl)VVR_ | |
| HMGCR | Ubiquitylation | K873 | -1.345 | _SK(gl)INLQDLQGACTKK_ | |
| HMGCR | Ubiquitylation | K885 | -1.690 | _SKINLQDLQGACTK(gl)K_ | |
| HMGCR | Ubiquitylation | K886 | -1.325 | _INLQDLQGACTKK(gl)_ | |
| HMOX1 | Ubiquitylation | K243 | -0.972 | _ASNK(gl)VQDSAPVETPR_ | |
| HMOX1 | Ubiquitylation | K256 | -1.769 | _GK(gl)PPLNTR_ | |
| ID2 | Phosphorylation | S14 | -0.139 | _NS(ph)LSDHSLGISR_ | |
| JUN | Phosphorylation | S58 | -0.167 | -1.247 | _AKNS(ph)DLLTSPDVGLLK_ |
| JUN | Phosphorylation | T62 | 2.545 | 1.674 | _NSDLLT(ph)SPDVGLLK_ |
| JUN | Phosphorylation | S63 | 2.030 | 1.458 | _NSDLLTS(ph)PDVGLLK_ |
| JUN | Ubiquitylation | K70 | 9.213 | _NSDLLTSPDVGLLK(gl)_ | |
| JUN | Phosphorylation | S73 | 1.499 | 0.845 | _LAS(ph)PELER_ |
| JUN | Phosphorylation | S243 | -0.642 | -1.399 | _LQALKEEPQTVPEMPGETPPLS(ph)PIDMESQER_ |
| JUN | Ubiquitylation | K309 | 1.034 | 0.155 | _EQVAQLK(gl)QK_ |
| MNAT1 | Phosphorylation | S279 | 0.003 | 0.225 | _AAS(ph)PQDLAGGYTSSLACHR_ |
| RPS6KB1 | Ubiquitylation | K99 | -0.316 | _VLGK(gl)GGYGK_ | |
| RPS6KB1 | Phosphorylation | S447 | -0.525 | -0.458 | _TPVS(ph)PVKFSPGDFWGR_ |
| SKP2 | Phosphorylation | S8 | -1.062 | _SNLGHPES(ph)PPRK_ | |
| SKP2 | Phosphorylation | S64 | -1.144 | -1.189 | _EEPDSENIPQELLSNLGHPES(ph)PPR_ |
| SKP2 | Phosphorylation | S75 | 0.512 | 0.657 | _SKGS(ph)DKDFVIVR_ |
| SKP2 | Ubiquitylation | K228 | -0.475 | _LSDPIVNTLAK(gl)NSNLVR_ | |
| SKP2 | Ubiquitylation | K420 | -1.178 | _LTLQK(gl)PSCL_ | |
| STAT1 | Phosphorylation | S727 | 1.377 | 0.974 | _LQTTDNLLPMS(ph)PEEFDEVSR_ |
| STAT5B | Phosphorylation | S194 | 0.270 | _IQAQFGPLAQLS(ph)PQER_ |
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