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PID_SYNDECAN_2_PATHWAY
(Pathway_1022)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
EPB41 2 0.960 -0.670 0.965 -0.443 -0.532 0.843 0.638
EPB41 2 0.960 -0.670
EZR 1 -0.240 -0.210 2.501 -2.209 0.246 0.091
CASK 1 2.050 -1.110
CASK 1 2.050 -1.110 -0.162 -0.217 -0.918 0.048 0.372
SDC2 1 -1.780 3.110
GNB2L1 1 1.000 -0.100 0.279 1.704
GNB2L1 1 1.000 -0.100 -0.278 -0.107 -0.424
RHOA 0 -0.510 1.370 -0.485 0.532 0.279
PRKACA 0 0.380 -0.680 -1.005 -0.697 0.234 0.487
BAX 0 1.590 -1.170 0.811 0.359
MAPK3 0
TGFB1 0 -0.550 1.050
EPHB2 0 -0.630 0.780 0.221
EPHB2 0 -0.630 0.780
SDCBP 0 -1.190 2.010 -1.188 0.299
SDCBP 0 -1.190 2.010 -0.575
ITGB1 0 0.390 -0.650 0.101 -0.036
ITGA5 0 0.320 -0.520 0.858 0.617
PRKCD 0 0.250 0.070 0.578 0.427
ITGA2 0 -0.370 0.660 0.847 0.435
CASP3 0 0.570 -0.390
HRAS 0 1.470 -0.520
NF1 0 1.000 -0.500 0.444 -0.190
SRC 0 0.050 0.470 -0.031

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
BAX Ubiquitylation K57 -1.174 _MGGEAPELALDPVPQDASTK(gl)K_
BAX Ubiquitylation K58 -1.718 -1.174 _MGGEAPELALDPVPQDASTKK(gl)_
BAX Ubiquitylation K64 0.708 1.306 _LSECLK(gl)R_
CASK Ubiquitylation K41 1.029 1.231 _ETGQQFAVK(gl)IVDVAK_
CASK Ubiquitylation K60 0.240 0.541 _FTSSPGLSTEDLK(gl)R_
CASK Phosphorylation S570 0.125 _TQSS(ph)SCEDLPSTTQPK_
CASK Phosphorylation S571 0.134 -0.032 _TQSSS(ph)CEDLPSTTQPK_
CASK Ubiquitylation K665 -0.631 _LENSK(gl)NGTAGLIPSPELQEWR_
CASK Ubiquitylation K691 1.108 _TK(gl)QEQQASCTWFGK_
CASK Ubiquitylation K703 0.627 _TKQEQQASCTWFGK(gl)K_
CASK Ubiquitylation K704 0.627 _TKQEQQASCTWFGK(gl)K_
CASP3 Ubiquitylation K11 -0.053 -0.687 _(ac)MENTENSVDSK(gl)SIK_
CASP3 Ubiquitylation K14 -0.455 -0.687 _SIK(gl)NLEPK_
CASP3 Ubiquitylation K57 -0.304 -1.817 _NFHK(gl)STGMTSR_
CASP3 Ubiquitylation K82 -0.268 -0.605 _NLK(gl)YEVR_
EPB41 Phosphorylation S95 2.058 1.653 _SQVS(ph)EEEGKEVESDKEK_
EPB41 Phosphorylation S188 0.343 0.603 _IEVKEES(ph)PQSK_
EPB41 Phosphorylation S191 0.304 _IEVKEESPQS(ph)K_
EPB41 Ubiquitylation K198 0.148 _AETELK(gl)ASQKPIRK_
EPB41 Ubiquitylation K237 1.265 1.069 _GQDLLK(gl)R_
EPB41 Ubiquitylation K361 0.451 _LAPNQTK(gl)ELEEK_
EPB41 Ubiquitylation K366 0.532 _ELEEK(gl)VMELHK_
EPB41 Ubiquitylation K372 0.922 _VMELHK(gl)SYR_
EPB41 Ubiquitylation K499 -0.476 _SK(gl)FLALGSK_
EPB41 Phosphorylation S542 0.751 0.712 _S(ph)LDGAAAVDSADR_
EPB41 Phosphorylation S551 -0.139 _SLDGAAAVDS(ph)ADRSPRPTSAPAITQGQVAEGGVLDASAK_
EPB41 Phosphorylation S555 -0.200 -1.109 _SLDGAAAVDSADRS(ph)PRPTSAPAITQGQVAEGGVLDASAK_
EPB41 Phosphorylation S560 -0.232 0.037 _SPRPTS(ph)APAITQGQVAEGGVLDASAK_
EPB41 Phosphorylation S709 0.307 _RLS(ph)THSPFR_
EPB41 Phosphorylation S712 -0.493 0.130 _LSTHS(ph)PFR_
EPB41 Ubiquitylation K1061 0.496 _EAK(gl)EQHPDMSVTK_
EPHB2 Ubiquitylation K578 -0.752 -0.618 _QSPEDVYFSK(gl)SEQLKPLK_
EPHB2 Ubiquitylation K583 0.445 0.124 _SEQLK(gl)PLK_
EPHB2 Ubiquitylation K617 0.339 _QK(gl)VIGAGEFGEVYK_
EPHB2 Ubiquitylation K649 -1.219 _TLK(gl)AGYTEK_
EPHB2 Phosphorylation S776 -0.147 -0.171 _FLEDDTS(ph)DPTYTSALGGK_
EPHB2 Phosphorylation S897 0.000 _LPS(ph)TSGSEGVPFR_
EPHB2 Phosphorylation T898 -0.329 0.424 _LPST(ph)SGSEGVPFR_
EZR Ubiquitylation K3 -0.313 -0.251 _PK(gl)PINVR_
EZR Ubiquitylation K79 0.172 -0.032 _ENPLQFK(gl)FR_
EZR Ubiquitylation K139 1.519 0.361 _FGDYNK(gl)EVHK_
EZR Ubiquitylation K162 1.580 0.660 _VMDQHK(gl)LTR_
EZR Ubiquitylation K253 -0.069 _NISFNDK(gl)K_
EZR Ubiquitylation K263 -0.786 _K(gl)APDFVFYAPR_
EZR Ubiquitylation K344 0.598 0.235 _EK(gl)EELMLR_
EZR Ubiquitylation K357 -0.003 _LQDYEEK(gl)TK_
EZR Ubiquitylation K359 0.051 _LQDYEEK(gl)TK_
EZR Ubiquitylation K450 0.393 0.174 _AK(gl)EAQDDLVK_
GNB2L1 Ubiquitylation K38 -0.238 0.350 _DK(gl)TIIMWK_
GNB2L1 Ubiquitylation K106 -0.290 _RFVGHTK(gl)DVLSVAFSSDNR_
GNB2L1 Ubiquitylation K130 0.632 _TIK(gl)LWNTLGVCK_
GNB2L1 Ubiquitylation K175 -0.554 -0.015 _LVK(gl)VWNLANCK_
GNB2L1 Ubiquitylation K183 -0.161 -0.282 _VWNLANCK(gl)_
GNB2L1 Ubiquitylation K185 -0.061 -0.249 _VWNLANCKLK(gl)_
GNB2L1 Ubiquitylation K257 -0.288 _YWLCAATGPSIK(gl)_
GNB2L1 Ubiquitylation K271 0.756 -0.007 _IIVDELK(gl)QEVISTSSK_
HRAS Ubiquitylation K170 -1.005 _K(gl)LNPPDESGPGCMSCK_
ITGA5 Phosphorylation S127 0.200 0.067 _LLESSLSS(ph)SEGEEPVEYK_
ITGA5 Phosphorylation S128 -0.087 _LLESSLSSS(ph)EGEEPVEYK_
ITGB1 Ubiquitylation K774 0.402 _MNAK(gl)WDTGENPIYK_
ITGB1 Ubiquitylation K784 -0.172 0.350 _WDTGENPIYK(gl)SAVTTVVNPK_
ITGB1 Ubiquitylation K794 0.755 0.604 _SAVTTVVNPK(gl)YEGK_
MAPK3 Phosphorylation Y204 -0.807 -2.487 _IADPEHDHTGFLTEY(ph)VATR_
MAPK3 Ubiquitylation K289 -0.608 _NYLQSLPSKTK(gl)_
NF1 Ubiquitylation K471 0.218 _MAPSLTFKEK(gl)_
NF1 Phosphorylation S864 -0.458 _SNSGLATYS(ph)PPMGPVSER_
NF1 Phosphorylation T2514 0.076 _GSEGYLAATYPTVGQT(ph)SPR_
NF1 Phosphorylation S2515 0.071 0.316 _GSEGYLAATYPTVGQTS(ph)PR_
NF1 Phosphorylation S2543 0.698 0.655 _S(ph)FDHLISDTK_
PRKACA Ubiquitylation K30 -0.143 _AKEDFLKK(gl)_
PRKACA Ubiquitylation K93 0.839 0.714 _QIEHTLNEK(gl)R_
PRKCD Ubiquitylation K138 -0.141 _SEDEAK(gl)FPTMNR_
PRKCD Ubiquitylation K222 0.185 0.658 _DTIFQK(gl)ER_
PRKCD Phosphorylation S302 -0.240 -0.222 _S(ph)DSASSEPVGIYQGFEK_
PRKCD Phosphorylation S304 0.378 0.289 _RSDS(ph)ASSEPVGIYQGFEK_
PRKCD Phosphorylation S506 -0.213 0.200 _AS(ph)TFCGTPDYIAPEILQGLK_
PRKCD Phosphorylation T507 -0.149 0.240 _AS(ph)TFCGTPDYIAPEILQGLK_
PRKCD Ubiquitylation K641 -2.000 _DYSNFDQEFLNEK(gl)AR_
PRKCD Phosphorylation S645 0.577 0.832 _ARLS(ph)YSDK_
PRKCD Phosphorylation S647 0.886 0.853 _ARLSYS(ph)DK_
RHOA Ubiquitylation K6 0.708 _K(gl)KLVIVGDGACGK_
RHOA Ubiquitylation K7 0.708 _K(gl)KLVIVGDGACGK_
RHOA Ubiquitylation K118 -0.408 _HFCPNVPIILVGNK(gl)K_
RHOA Ubiquitylation K119 -0.408 _HFCPNVPIILVGNK(gl)K_
RHOA Ubiquitylation K135 -0.528 -0.796 _MK(gl)QEPVKPEEGRDMANR_
RHOA Ubiquitylation K162 0.345 0.453 _IGAFGYMECSAK(gl)TK_
SDC2 Ubiquitylation K193 -0.696 -0.929 _KPSSAAYQK(gl)APTK_
SDC2 Ubiquitylation K197 -0.160 0.647 _APTK(gl)EFYA_
SDCBP Phosphorylation S6 0.120 0.427 _(ac)SLYPS(ph)LEDLKVDK_
SDCBP Ubiquitylation K35 -0.806 _(ac)SLYPSLEDLKVDK(gl)_
SDCBP Ubiquitylation K129 0.064 0.792 _RAEIK(gl)QGIR_
SDCBP Ubiquitylation K199 -0.134 -0.436 _VLK(gl)QAFGEK_
SDCBP Ubiquitylation K243 0.141 _ITSIVK(gl)DSSAAR_
SRC Phosphorylation S17 -0.604 -0.689 _S(ph)LEPAENVHGAGGGAFPASQTPSKPASADGHR_
SRC Phosphorylation S75 0.060 0.331 _LFGGFNSSDTVTS(ph)PQR_
TGFB1 Ubiquitylation K50 -0.557 _GQILSK(gl)LR_


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