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Query: EPB41

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EPB41 2 7.517 0.960 -0.670
EPB41 2 7.517 0.960 -0.670 0.965 -0.443 -0.532 0.843 0.638

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EPB41 Phosphorylation S95 2.058 1.653 _SQVS(ph)EEEGKEVESDKEK_
EPB41 Ubiquitylation K237 1.265 1.069 _GQDLLK(gl)R_
EPB41 Phosphorylation S542 0.751 0.712 _S(ph)LDGAAAVDSADR_
EPB41 Phosphorylation S188 0.343 0.603 _IEVKEES(ph)PQSK_
EPB41 Phosphorylation S709 0.307 _RLS(ph)THSPFR_
EPB41 Phosphorylation S191 0.304 _IEVKEESPQS(ph)K_
EPB41 Phosphorylation S712 -0.493 0.130 _LSTHS(ph)PFR_
EPB41 Phosphorylation S560 -0.232 0.037 _SPRPTS(ph)APAITQGQVAEGGVLDASAK_
EPB41 Phosphorylation S555 -0.200 -1.109 _SLDGAAAVDSADRS(ph)PRPTSAPAITQGQVAEGGVLDASAK_
EPB41 Ubiquitylation K198 0.148 _AETELK(gl)ASQKPIRK_
EPB41 Ubiquitylation K361 0.451 _LAPNQTK(gl)ELEEK_
EPB41 Ubiquitylation K366 0.532 _ELEEK(gl)VMELHK_
EPB41 Ubiquitylation K372 0.922 _VMELHK(gl)SYR_
EPB41 Ubiquitylation K499 -0.476 _SK(gl)FLALGSK_
EPB41 Phosphorylation S551 -0.139 _SLDGAAAVDS(ph)ADRSPRPTSAPAITQGQVAEGGVLDASAK_
EPB41 Ubiquitylation K1061 0.496 _EAK(gl)EQHPDMSVTK_

Background Information for EPB41:





Protein-protein Interactions for EPB41

Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in EPB41

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members SAB_dom IPR007477 1.02
Category members Band_4.1_C IPR008379 1.02
Category members Band_41_protein IPR021187 1.02
Category members Ez/rad/moesin_like IPR000798 0.38
Category members FERM_N IPR018979 0.36
Category members FERM_PH-like_C IPR018980 0.35
Category members Band_41_fam IPR019750 0.33
Category members FERM-adjacent IPR014847 0.08
Category members FERM_domain IPR000299 0
Category members FERM_central IPR019748 0
Category members Band_41_domain IPR019749 0


Protein complexes (CORUM database) featuring EPB41

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring EPB41

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0043234 protein complex Database 2.73
Category members Pathway Pathway_413 KEGG_TIGHT_JUNCTION 0 2.08
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0030507 spectrin binding Database 1.12
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members GO Category GO:0005198 structural molecule activity Database 0.94
Category members GO Category GO:0030866 cortical actin cytoskeleton organization Database 0.89
Category members GO Category GO:0005516 calmodulin binding Database 0.74
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0008092 cytoskeletal protein binding Database 0.5
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0008091 spectrin Database 0.43
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0030863 cortical cytoskeleton Database 0.24
Category members Pathway Pathway_1022 PID_SYNDECAN_2_PATHWAY 0 0.08
Category members Disease phenotype PYROPOIKILOCYTOSIS_HEREDITARY PYROPOIKILOCYTOSIS HEREDITARY Database 0
Category members GO Category GO:0005200 structural constituent of cytoskeleton Database 0
Category members GO Category GO:0005545 1-phosphatidylinositol binding Database 0
Category members GO Category GO:0008015 blood circulation Database 0
Category members GO Category GO:0014731 spectrin-associated cytoskeleton Database 0
Category members GO Category GO:0019898 extrinsic to membrane Database 0
Category members GO Category GO:0032092 positive regulation of protein binding Database 0


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