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Query: SDC2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SDC2 1 3.597 -1.780 3.110

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SDC2 Ubiquitylation K197 -0.160 0.647 _APTK(gl)EFYA_
SDC2 Ubiquitylation K193 -0.696 -0.929 _KPSSAAYQK(gl)APTK_

Background Information for SDC2:


Pubmed-SDC2 »
Uniprot-SDC2 »
Biogrid-SDC2 »
ProteomicsDB-SDC2 »

Tumorportal-SDC2 »
COSMIC-SDC2 »
GenomeRNAi-SDC2 »
Genecards-SDC2


Protein-protein Interactions for SDC2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATXN3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX4 Cat. description Hein, Mann, Cell 2015
Category members IP bait POLR2F Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNCRIP Cat. description Hein, Mann, Cell 2015
Category members IP bait TMPO Cat. description Hein, Mann, Cell 2015
Category members IP bait TNKS Cat. description Hein, Mann, Cell 2015
Category members IP bait TPX2 Cat. description Hein, Mann, Cell 2015
Category members IP bait EFNB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR183 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LIPG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SDC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SDC2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Neurexin-like IPR003585 0
Category members Syndecan/Neurexin_dom IPR027789 0


Protein complexes (CORUM database) featuring SDC2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SDC2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members Pathway Pathway_73 REACTOME_GLYCOSAMINOGLYCAN_METABOLISM 0 1.71
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0030203 glycosaminoglycan metabolic process Database 1.44
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005796 Golgi lumen Database 0.64
Category members Pathway Pathway_471 REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM 0 0.6
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0008092 cytoskeletal protein binding Database 0.5
Category members Pathway Pathway_79 REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM 0 0.49
Category members GO Category GO:0030204 chondroitin sulfate metabolic process Database 0.36
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_478 REACTOME_HS_GAG_BIOSYNTHESIS 0 0.31
Category members Pathway Pathway_34 REACTOME_METABOLISM_OF_CARBOHYDRATES 0 0.31
Category members GO Category GO:0030165 PDZ domain binding Database 0.29
Category members GO Category GO:0030198 extracellular matrix organization Database 0.26
Category members GO Category GO:0007603 phototransduction, visible light Database 0.25
Category members GO Category GO:0048813 dendrite morphogenesis Database 0.23
Category members Pathway Pathway_479 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS 0 0.21
Category members GO Category GO:0006024 glycosaminoglycan biosynthetic process Database 0.18
Category members GO Category GO:0001523 retinoid metabolic process Database 0.1
Category members Pathway Pathway_1022 PID_SYNDECAN_2_PATHWAY 0 0.08
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members GO Category GO:0043202 lysosomal lumen Database 0.07
Category members GO Category GO:0006027 glycosaminoglycan catabolic process Database 0.05
Category members Pathway Pathway_76 REACTOME_HS_GAG_DEGRADATION 0 0.03
Category members Pathway Pathway_1217 KEGG_CELL_ADHESION_MOLECULES_CAMS 0 0
Category members Pathway Pathway_432 PID_SHP2_PATHWAY 0 0
Category members Pathway Pathway_657 PID_FGF_PATHWAY 0 0
Category members Pathway Pathway_922 KEGG_ECM_RECEPTOR_INTERACTION 0 0
Category members GO Category GO:0001666 response to hypoxia Database 0
Category members GO Category GO:0008150 biological_process Database 0
Category members GO Category GO:0031000 response to caffeine Database 0
Category members GO Category GO:0042060 wound healing Database 0
Category members GO Category GO:0043025 neuronal cell body Database 0
Category members GO Category GO:0048814 regulation of dendrite morphogenesis Database 0


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