RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
GNAI3	1	0.750	-0.890
GNAI3	1	0.750	-0.890	0.217			-0.334	-0.374
GNAO1	1	1.200	-1.320
RAF1	1	2.020	-1.230
KRAS	1	-0.510	0.620				1.031	0.887
KRAS	1	-0.510	0.620				0.246	-0.346
IGF1R	1	-0.490	0.750				1.476	0.714
MAP2K1	1	-1.590	2.780
SDC2	1	-1.780	3.110
NRAS	1	1.810	-0.720				0.246	-0.346
IFNGR1	0	-1.300	2.410
GNAI1	0	-0.580	0.990
GNAI2	0	0.190	-0.520
GNAL	0	1.660	-1.170
GNAS	0	0.840	-0.750
GNAT1	0	-0.110	-0.270
GNAT2	0	0.140	-0.880
GNAT3	0	1.110	-0.500
RHOA	0	-0.510	1.370	-0.485			0.532	0.279
PRKACA	0	0.380	-0.680		-1.005	-0.697	0.234	0.487
PAG1	0	-0.550	1.760
GAB1	0	1.950	-1.110
STAT1	0	-0.550	0.170
SOS1	0	0.500	-0.620	-0.570
PIK3CA	0
MAP2K2	0	-0.610	0.080
MAP2K2	0	-0.610	0.080
GNAI1	0	-0.580	0.990	0.116			-0.747
KDR	0	0.860	-0.680
MLLT4	0	-1.080	1.480
MLLT4	0	-1.080	1.480				-1.880	-0.065
MLLT4	0	-1.080	1.480				0.689	0.492
PIK3R1	0	1.910	-1.220				-0.441	0.147
EGFR	0	-0.580	0.520				0.513	0.090
ARHGAP35	0	1.030	-0.620	-0.833			0.397	0.020
JAK1	0	0.190	-0.100		-1.504	-0.381		-0.438
IRS1	0
HRAS	0	1.470	-0.520
GRB2	0	-0.240	0.300		-1.021	0.057	0.906
PTPN11	0	-0.210	-0.400	0.644			1.053	0.451
LCK	0	-0.490	1.390				0.295	0.576

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
ARHGAP35	Phosphorylation	S975	-0.388	-0.423	_AGS(ph)PLCNSNLQDSEEDIEPSYSLFR_
ARHGAP35	Phosphorylation	S1072		-0.719	_SVS(ph)SSPWLPQDGFDPSDYAEPMDAVVKPR_
ARHGAP35	Phosphorylation	S1150	1.218	0.094	_KVS(ph)IVSKPVLYR_
ARHGAP35	Phosphorylation	S1179	0.400	0.591	_TSFSVGS(ph)DDELGPIR_
EGFR	Phosphorylation	T693	0.486	-0.139	_ELVEPLT(ph)PSGEAPNQALLR_
EGFR	Phosphorylation	S991		-0.041	_MHLPS(ph)PTDSNFYR_
GAB1	Phosphorylation	S266	0.756	0.551	_SYS(ph)HDVLPK_
GAB1	Phosphorylation	S367	0.230	0.176	_TAS(ph)DTDSSYCIPTAGMS(ph)PSR_
GAB1	Phosphorylation	T369		-0.352	_TASDT(ph)DSSYCIPTAGMS(ph)PSR_
GAB1	Phosphorylation	S381	-0.481	0.139	_TASDTDSSYCIPTAGM(ox)S(ph)PSR_
GAB1	Phosphorylation	S401	0.266	0.788	_DAS(ph)SQDCYDIPR_
GAB1	Phosphorylation	S402	0.328	0.633	_DASS(ph)QDCYDIPR_
GAB1	Phosphorylation	S419		0.540	_SSS(ph)LEGFHNHFK_
GNAI1	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAI1	Ubiquitylation	K92	0.873	0.567	_LK(gl)IDFGDSAR_
GNAI2	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAI3	Ubiquitylation	K29	0.529	-0.094	_NLREDGEK(gl)AAK_
GNAI3	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAI3	Ubiquitylation	K92	1.569		_LK(gl)IDFGEAAR_
GNAI3	Ubiquitylation	K349	-0.221	-0.339	_NNLK(gl)ECGLY_
GNAL	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAO1	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAS	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAT1	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAT2	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAT3	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GRB2	Ubiquitylation	K10	0.146		_YDFK(gl)ATADDELSFK_
GRB2	Ubiquitylation	K20	-0.078		_ATADDELSFK(gl)R_
GRB2	Ubiquitylation	K69	-0.362	0.641	_AK(gl)AEEMLSK_
GRB2	Ubiquitylation	K76	0.754		_AEEMLSK(gl)QR_
GRB2	Ubiquitylation	K109	0.381	-0.002	_FGNDVQHFK(gl)VLR_
HRAS	Ubiquitylation	K170	-1.005		_K(gl)LNPPDESGPGCMSCK_
IFNGR1	Ubiquitylation	K299	-0.875	-0.201	_SATLETK(gl)PESK_
IGF1R	Ubiquitylation	K47		1.146	_NDYQQLK(gl)R_
IGF1R	Ubiquitylation	K1033	5.779		_VAIK(gl)TVNEAASMR_
IGF1R	Ubiquitylation	K1168	0.191		_K(gl)GGKGLLPVR_
IGF1R	Ubiquitylation	K1171	0.232		_GGK(gl)GLLPVR_
IRS1	Phosphorylation	S1101	-0.078		_HSS(ph)ETFSSTPSATR_
JAK1	Ubiquitylation	K227	-0.405		_YIPETLNK(gl)SIR_
JAK1	Ubiquitylation	K249	0.116	0.771	_DFLK(gl)EFNNK_
JAK1	Ubiquitylation	K559	-0.478		_EISNLLVATK(gl)K_
KDR	Ubiquitylation	K1064		-1.119	_DIYK(gl)DPDYVR_
KRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
KRAS	Ubiquitylation	K235	0.591	0.087	_TVDTK(gl)QAQDLAR_
KRAS	Ubiquitylation	K254	-0.450	-0.156	_SYGIPFIETSAK(gl)TR_
LCK	Phosphorylation	T37		-0.435	_YRPENTPEPVSTSVSHYGAEPT(ph)TVSPCPSSSAK_
LCK	Ubiquitylation	K191	-0.112	0.264	_ESETTK(gl)GAYSLSIR_
LCK	Ubiquitylation	K235	0.323		_AQFDTLQK(gl)LVK_
LCK	Ubiquitylation	K259		-1.613	_LTTVCPTVK(gl)PQTQGLAK_
MAP2K1	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K1	Phosphorylation	S385		0.066	_RSDAEEVDFAGWLCSTIGLNQPS(ph)TPTHAAGV_
MAP2K1	Phosphorylation	T386		0.377	_RSDAEEVDFAGWLCSTIGLNQPST(ph)PTHAAGV_
MAP2K2	Phosphorylation	S23	0.873	0.258	_RKPVLPALTINPTIAEGPS(ph)PTSEGASEANLVDLQK_
MAP2K2	Phosphorylation	T25		0.439	_RKPVLPALTINPTIAEGPSPT(ph)SEGASEANLVDLQK_
MAP2K2	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K2	Phosphorylation	S293		-0.361	_ELEAIFGRPVVDGEEGEPHS(ph)ISPR_
MAP2K2	Phosphorylation	S295	-0.234	0.026	_ELEAIFGRPVVDGEEGEPHSIS(ph)PR_
MAP2K2	Phosphorylation	T394	0.570	0.158	_LNQPGT(ph)PTR_
MLLT4	Phosphorylation	S216	0.045	0.221	_TIS(ph)NPEVVMK_
MLLT4	Ubiquitylation	K1042	-0.441		_SVVK(gl)GGAADVDGR_
MLLT4	Phosphorylation	S1083	-1.359		_TSS(ph)VVTLEVAK_
MLLT4	Phosphorylation	S1107	0.858	0.054	_QGAIYHGLATLLNQPS(ph)PMMQR_
MLLT4	Phosphorylation	S1172	-0.906	-1.359	_S(ph)SPNVANQPPS(ph)PGGK_
MLLT4	Phosphorylation	S1173	-0.957	-1.174	_SS(ph)PNVANQPPS(ph)PGGK_
MLLT4	Phosphorylation	S1182	-0.606	-0.764	_SSPNVANQPPS(ph)PGGK_
MLLT4	Phosphorylation	T1211		-0.552	_ITSVSTGNLCTEEQT(ph)PPPRPEAYPIPTQTYTR_
MLLT4	Phosphorylation	S1275	0.682	1.367	_S(ph)QEELREDK_
MLLT4	Phosphorylation	S1696	-2.036	-1.851	_DYEPPS(ph)PSPAPGAPPPPPQR_
MLLT4	Phosphorylation	S1698		-3.791	_DYEPPSPS(ph)PAPGAPPPPPQR_
MLLT4	Phosphorylation	S1721	0.872	0.984	_TQVLS(ph)PDSLFTAK_
MLLT4	Phosphorylation	S1779	0.084	0.426	_SQDADS(ph)PGSSGAPENLTFK_
MLLT4	Phosphorylation	S1799	0.590	0.104	_LFS(ph)QGQDVSNK_
NRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
PAG1	Phosphorylation	S288	0.574	0.875	_EGGEAEESATDTTS(ph)ETNK_
PIK3CA	Ubiquitylation	K864	0.390	0.588	_NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA	Ubiquitylation	K868	0.204	0.651	_NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA	Ubiquitylation	K974	-0.273		_GAQECTK(gl)TREFER_
PRKACA	Ubiquitylation	K30	-0.143		_AKEDFLKK(gl)_
PRKACA	Ubiquitylation	K93	0.839	0.714	_QIEHTLNEK(gl)R_
PTPN11	Ubiquitylation	K124	0.562		_EAEK(gl)LLTEK_
RAF1	Phosphorylation	S29	0.028	-0.571	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	T31	0.028	-0.669	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	S244		0.053	_YSTPHAFTFNTSS(ph)PSSEGSLSQR_
RAF1	Phosphorylation	S259	-0.069	0.054	_STS(ph)TPNVHM(ox)VSTTLPVDSR_
RAF1	Phosphorylation	S301		-0.651	_SHSESASPSALSSSPNNLS(ph)PTGWSQPK_
RAF1	Phosphorylation	T303		-0.664	_SHSESASPSALSSSPNNLSPT(ph)GWSQPK_
RAF1	Phosphorylation	S497		-0.449	_SRWS(ph)GSQQVEQPTGSVLWMAPEVIR_
RAF1	Phosphorylation	S621	0.212	0.271	_SAS(ph)EPSLHR_
RAF1	Phosphorylation	S642	-0.197	0.463	_AAHTEDINACTLTTS(ph)PR_
RHOA	Ubiquitylation	K6	0.708		_K(gl)KLVIVGDGACGK_
RHOA	Ubiquitylation	K7	0.708		_K(gl)KLVIVGDGACGK_
RHOA	Ubiquitylation	K118	-0.408		_HFCPNVPIILVGNK(gl)K_
RHOA	Ubiquitylation	K119	-0.408		_HFCPNVPIILVGNK(gl)K_
RHOA	Ubiquitylation	K135	-0.528	-0.796	_MK(gl)QEPVKPEEGRDMANR_
RHOA	Ubiquitylation	K162	0.345	0.453	_IGAFGYMECSAK(gl)TK_
SDC2	Ubiquitylation	K193	-0.696	-0.929	_KPSSAAYQK(gl)APTK_
SDC2	Ubiquitylation	K197	-0.160	0.647	_APTK(gl)EFYA_
SOS1	Phosphorylation	S1082	0.278		_IPESETESTASAPNS(ph)PR_
SOS1	Phosphorylation	S1166	0.097	-0.094	_RPESAPAES(ph)SPSK_
STAT1	Phosphorylation	S727	1.377	0.974	_LQTTDNLLPMS(ph)PEEFDEVSR_