bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: GNAO1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GNAO1 1 0.984 1.200 -1.320
GNAO1 1 0.984 1.200 -1.320 0.217 -0.334 -0.374

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GNAO1 Ubiquitylation K29 0.529 -0.094 _NLREDGEK(gl)AAK_
GNAO1 Ubiquitylation K349 -0.221 -0.339 _NNLK(gl)ECGLY_
GNAO1 Ubiquitylation K53 -1.168 -0.413 _LLLLGAGESGK(gl)STIVK_
GNAO1 Ubiquitylation K92 1.569 _LK(gl)IDFGEAAR_

Background Information for GNAO1:


Pubmed-GNAO1 »
Uniprot-GNAO1 »
Biogrid-GNAO1 »
ProteomicsDB-GNAO1 »

Tumorportal-GNAO1 »
COSMIC-GNAO1 »
GenomeRNAi-GNAO1 »
Genecards-GNAO1


Protein-protein Interactions for GNAO1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait TMOD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait ARMC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C14orf104 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD69 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DGUOK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DUSP22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GJB7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GNAI1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GNAI2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GNAI3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GNG3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HAX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HOXB5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait JSRP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIFAP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUFIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GNAO1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Small_GTPase_ARF/SAR IPR006689 0.8
Category members GproteinA_insert IPR011025 0.18
Category members Gprotein_alpha_su IPR001019 0.02
Category members Gprotein_alpha_I IPR001408 0
Category members Fungi_Gprotein_alpha IPR002975 0


Protein complexes (CORUM database) featuring GNAO1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GNAO1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0007186 G-protein coupled receptor signaling pathway Database 1.53
Category members Pathway Pathway_645 PID_CXCR4_PATHWAY 0 1.42
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_237 PID_LYSOPHOSPHOLIPID_PATHWAY 0 1.09
Category members Pathway Pathway_5 REACTOME_INTEGRATION_OF_ENERGY_METABOLISM 0 0.9
Category members Pathway Pathway_256 REACTOME_SIGNALING_BY_GPCR 0 0.83
Category members Pathway Pathway_736 PID_S1P_META_PATHWAY 0 0.73
Category members GO Category GO:0042493 response to drug Database 0.66
Category members Pathway Pathway_1078 PID_S1P_S1P2_PATHWAY 0 0.62
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members GO Category GO:0005622 intracellular Database 0.32
Category members Pathway Pathway_286 KEGG_LONG_TERM_DEPRESSION 0 0.31
Category members Pathway Pathway_260 REACTOME_OPIOID_SIGNALLING 0 0.28
Category members Pathway Pathway_987 PID_S1P_S1P3_PATHWAY 0 0.28
Category members Pathway Pathway_433 PID_ER_NONGENOMIC_PATHWAY 0 0.23
Category members GO Category GO:0043547 positive regulation of GTPase activity Database 0.21
Category members GO Category GO:0042542 response to hydrogen peroxide Database 0.19
Category members Pathway Pathway_428 PID_THROMBIN_PAR1_PATHWAY 0 0.18
Category members Pathway Pathway_696 PID_S1P_S1P4_PATHWAY 0 0.18
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members GO Category GO:0031175 neuron projection development Database 0.12
Category members GO Category GO:0031234 extrinsic to cytoplasmic side of plasma membrane Database 0.1
Category members Pathway Pathway_984 PID_HEDGEHOG_GLI_PATHWAY 0 0.1
Category members Pathway Pathway_270 REACTOME_REGULATION_OF_INSULIN_SECRETION 0 0.09
Category members GO Category GO:0043005 neuron projection Database 0.08
Category members GO Category GO:0019001 guanyl nucleotide binding Database 0.07
Category members GO Category GO:0008016 regulation of heart contraction Database 0.04
Category members GO Category GO:0031683 G-protein beta/gamma-subunit complex binding Database 0.02
Category members GO Category GO:0010243 response to organonitrogen compound Database 0.02
Category members Pathway Pathway_1100 REACTOME_G_PROTEIN_ACTIVATION 0 0
Category members Pathway Pathway_227 REACTOME_PLC_BETA_MEDIATED_EVENTS 0 0
Category members Pathway Pathway_234 PID_ENDOTHELIN_PATHWAY 0 0
Category members Pathway Pathway_244 KEGG_MELANOGENESIS 0 0
Category members Pathway Pathway_269 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE 0 0
Category members Pathway Pathway_624 PID_AR_NONGENOMIC_PATHWAY 0 0
Category members Pathway Pathway_655 PID_CXCR3_PATHWAY 0 0
Category members Pathway Pathway_683 PID_S1P_S1P1_PATHWAY 0 0
Category members Disease phenotype Early_infantile_epileptic_encephalopathy Early infantile epileptic encephalopathy Database 0
Category members Disease phenotype Epileptic_encephalopathy Epileptic encephalopathy Database 0
Category members GO Category GO:0004871 signal transducer activity Database 0
Category members GO Category GO:0005834 heterotrimeric G-protein complex Database 0
Category members GO Category GO:0006936 muscle contraction Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway Database 0
Category members GO Category GO:0007212 dopamine receptor signaling pathway Database 0
Category members GO Category GO:0007568 aging Database 0
Category members GO Category GO:0007626 locomotory behavior Database 0
Category members GO Category GO:0009987 cellular process Database 0
Category members GO Category GO:0014070 response to organic cyclic compound Database 0
Category members GO Category GO:0030900 forebrain development Database 0
Category members GO Category GO:0031821 G-protein coupled serotonin receptor binding Database 0
Category members GO Category GO:0031852 mu-type opioid receptor binding Database 0
Category members GO Category GO:0032794 GTPase activating protein binding Database 0
Category members GO Category GO:0034097 response to cytokine Database 0
Category members GO Category GO:0043278 response to morphine Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0051430 corticotropin-releasing hormone receptor 1 binding Database 0
Category members GO Category GO:0051926 negative regulation of calcium ion transport Database 0


.

© Copyright Svejstrup Laboratory 2015