Results for the Category
REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE
(Pathway_269)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| GNAO1 | 1 | 1.200 | -1.320 | 0.217 | -0.334 | -0.374 | ||
| CACNB2 | 1 | 1.170 | -1.170 | |||||
| GNB1 | 0 | -0.700 | 0.650 | 0.713 | 0.504 | 0.538 | ||
| GNB3 | 0 | -1.020 | 1.280 | 0.713 | 0.504 | 0.538 | ||
| GNB4 | 0 | 0.410 | -0.240 | 0.137 | 0.627 | 1.296 | ||
| GNB4 | 0 | 0.410 | -0.240 | |||||
| GNAI1 | 0 | -0.580 | 0.990 | 0.116 | -0.747 | |||
| GNG4 | 0 | 0.310 | -0.680 | |||||
| GNB2 | 0 | 0.120 | -0.090 | 0.137 | 0.627 | 1.296 | ||
| GNG12 | 0 | 1.160 | -1.150 | -1.317 | ||||
| GNG12 | 0 | 1.160 | -1.150 | |||||
| GNG5 | 0 | -0.100 | -0.480 | |||||
| ADCY6 | 0 | -0.720 | 0.740 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| ADCY6 | Phosphorylation | S54 | -1.434 | -1.374 | _DAEPPS(ph)PTPAGPPR_ |
| ADCY6 | Ubiquitylation | K80 | 0.473 | 0.937 | _GK(gl)ELGLR_ |
| ADCY6 | Ubiquitylation | K568 | 1.007 | 0.799 | _AMLAK(gl)LQR_ |
| ADCY6 | Phosphorylation | S576 | -0.020 | _ANS(ph)MEGLMPR_ | |
| CACNB2 | Phosphorylation | S426 | 2.503 | _S(ph)ASQAEEEPSVEPVK_ | |
| CACNB2 | Phosphorylation | S428 | 1.622 | 0.834 | _SAS(ph)QAEEEPSVEPVK_ |
| GNAI1 | Ubiquitylation | K92 | 0.873 | 0.567 | _LK(gl)IDFGDSAR_ |
| GNAO1 | Ubiquitylation | K29 | 0.529 | -0.094 | _NLREDGEK(gl)AAK_ |
| GNAO1 | Ubiquitylation | K92 | 1.569 | _LK(gl)IDFGEAAR_ | |
| GNAO1 | Ubiquitylation | K349 | -0.221 | -0.339 | _NNLK(gl)ECGLY_ |
| GNB1 | Ubiquitylation | K23 | -0.282 | _K(gl)ACADATLSQITNNIDPVGR_ | |
| GNB1 | Ubiquitylation | K209 | -0.296 | -0.249 | _LFVSGACDASAK(gl)LWDVR_ |
| GNB2 | Ubiquitylation | K23 | -0.095 | 0.033 | _K(gl)ACGDSTLTQITAGLDPVGR_ |
| GNB2 | Ubiquitylation | K209 | 0.251 | 0.419 | _TFVSGACDASIK(gl)LWDVR_ |
| GNB3 | Ubiquitylation | K23 | -0.282 | _K(gl)ACADATLSQITNNIDPVGR_ | |
| GNB3 | Ubiquitylation | K209 | -0.296 | -0.249 | _LFVSGACDASAK(gl)LWDVR_ |
| GNB4 | Ubiquitylation | K23 | -0.095 | 0.033 | _K(gl)ACGDSTLTQITAGLDPVGR_ |
| GNB4 | Ubiquitylation | K23 | -0.030 | _K(gl)ACNDATLVQITSNMDSVGR_ | |
| GNB4 | Ubiquitylation | K209 | 0.251 | 0.419 | _TFVSGACDASIK(gl)LWDVR_ |
| GNB4 | Ubiquitylation | K209 | 0.019 | _TFVSGACDASSK(gl)LWDIR_ | |
| GNG12 | Ubiquitylation | K4 | 0.230 | 0.493 | _(ac)SSK(gl)TASTNNIAQAR_ |
| GNG12 | Ubiquitylation | K34 | 0.515 | 1.067 | _VSK(gl)ASADLMSYCEEHAR_ |
| GNG4 | Ubiquitylation | K24 | 1.031 | 0.205 | _KAVEQLK(gl)MEACMDR_ |
| GNG5 | Ubiquitylation | K11 | -0.523 | 0.125 | _(ac)SGSSSVAAMK(gl)K_ |
| GNG5 | Ubiquitylation | K12 | 0.232 | 0.466 | _K(gl)VVQQLR_ |
| GNG5 | Ubiquitylation | K27 | -0.760 | 0.148 | _VK(gl)VSQAAADLK_ |
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