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Query: CACNB2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CACNB2 1 3.337 1.170 -1.170

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CACNB2 Phosphorylation S428 1.622 0.834 _SAS(ph)QAEEEPSVEPVK_
CACNB2 Phosphorylation S426 2.503 _S(ph)ASQAEEEPSVEPVK_

Background Information for CACNB2:


Pubmed-CACNB2 »
Uniprot-CACNB2 »
Biogrid-CACNB2 »
ProteomicsDB-CACNB2 »

Tumorportal-CACNB2 »
COSMIC-CACNB2 »
GenomeRNAi-CACNB2 »
Genecards-CACNB2


Protein-protein Interactions for CACNB2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CACNB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CACNB3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CACNB2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members GK/Ca_channel_bsu IPR008145 1.36
Category members VDCC_L_bsu IPR000584 0
Category members SH3_domain IPR001452 0


Protein complexes (CORUM database) featuring CACNB2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CACNB2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members Pathway Pathway_673 REACTOME_AXON_GUIDANCE 0 1.06
Category members Pathway Pathway_5 REACTOME_INTEGRATION_OF_ENERGY_METABOLISM 0 0.9
Category members GO Category GO:0042383 sarcolemma Database 0.36
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members GO Category GO:0070588 calcium ion transmembrane transport Database 0.25
Category members GO Category GO:0007268 synaptic transmission Database 0.23
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members Pathway Pathway_270 REACTOME_REGULATION_OF_INSULIN_SECRETION 0 0.09
Category members GO Category GO:0005262 calcium channel activity Database 0.08
Category members Pathway Pathway_1009 REACTOME_NCAM1_INTERACTIONS 0 0.04
Category members Pathway Pathway_1007 KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC 0 0.03
Category members Pathway Pathway_1008 KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM 0 0
Category members Pathway Pathway_1010 REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH 0 0
Category members Pathway Pathway_139 REACTOME_NEURONAL_SYSTEM 0 0
Category members Pathway Pathway_140 REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES 0 0
Category members Pathway Pathway_198 KEGG_CARDIAC_MUSCLE_CONTRACTION 0 0
Category members Pathway Pathway_262 KEGG_DILATED_CARDIOMYOPATHY 0 0
Category members Pathway Pathway_269 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE 0 0
Category members Pathway Pathway_715 KEGG_MAPK_SIGNALING_PATHWAY 0 0
Category members Disease phenotype BRUGADA_SYNDROME BRUGADA SYNDROME Database 0
Category members GO Category GO:0005245 voltage-gated calcium channel activity Database 0
Category members GO Category GO:0005891 voltage-gated calcium channel complex Database 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0006816 calcium ion transport Database 0
Category members GO Category GO:0007528 neuromuscular junction development Database 0
Category members GO Category GO:0007601 visual perception Database 0
Category members GO Category GO:0008331 high voltage-gated calcium channel activity Database 0
Category members GO Category GO:0051928 positive regulation of calcium ion transport Database 0
Category members GO Category GO:0070509 calcium ion import Database 0


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