RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
SPTBN1	3	-2.120	3.900	0.059	-0.418	-0.700	0.255	0.415
SPTB	2	-0.050	0.120
SPTB	2	-0.050	0.120	0.059	-0.418	-0.700	0.255	0.415
FYN	1	1.080	-1.100
FYN	1	1.080	-1.100
RAF1	1	2.020	-1.230
KRAS	1	-0.510	0.620				1.031	0.887
KRAS	1	-0.510	0.620				0.246	-0.346
CACNB2	1	1.170	-1.170
MAP2K1	1	-1.590	2.780
SPTBN2	1	0.870	0.420				0.258	0.313
SPTAN1	1	1.040	-0.790
SPTAN1	1	1.040	-0.790		-0.323	-0.738	0.512	0.509
NRAS	1	1.810	-0.720				0.246	-0.346
FGFR1	0	0.210	0.150
MAPK3	0
SOS1	0	0.500	-0.620	-0.570
CREB1	0	1.080	-0.800			-1.027
MAP2K2	0	-0.610	0.080
MAP2K2	0	-0.610	0.080
COL4A2	0	-0.170	0.350				-0.692	-0.297
SPTBN5	0	-0.570	0.660				-0.508
COL6A1	0	0.390	0.000
COL6A2	0	-0.530	0.950
YWHAB	0				0.628	-0.543
YWHAB	0			0.507			0.271	0.503
CDK1	0	-0.370	0.080	-0.202	-0.884	-0.107	-0.097	-0.501
HRAS	0	1.470	-0.520
GRB2	0	-0.240	0.300		-1.021	0.057	0.906
COL4A1	0	1.810	-1.260					-0.162
AGRN	0	-0.130	0.060				-0.939
CACNA1H	0	-0.360	-0.020					0.124
SRC	0	0.050	0.470	-0.031

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
CACNB2	Phosphorylation	S426	2.503		_S(ph)ASQAEEEPSVEPVK_
CACNB2	Phosphorylation	S428	1.622	0.834	_SAS(ph)QAEEEPSVEPVK_
CDK1	Ubiquitylation	K6	0.011	-0.784	_(ac)M(ox)EDYTK(gl)IEK_
CDK1	Ubiquitylation	K20	-0.327	-0.270	_IGEGTYGVVYK(gl)GR_
CDK1	Ubiquitylation	K33	0.736	0.239	_TTGQVVAMK(gl)K_
CDK1	Ubiquitylation	K34		-0.306	_TTGQVVAMKK(gl)_
CDK1	Ubiquitylation	K58	0.312	-0.262	_EISLLK(gl)ELR_
CDK1	Ubiquitylation	K136		-0.468	_DLK(gl)PQNLLIDDK(gl)GTIK_
CDK1	Ubiquitylation	K145	0.161	-0.954	_DLKPQNLLIDDK(gl)GTIK_
CDK1	Ubiquitylation	K149		-0.038	_GTIK(gl)LADFGLAR_
CDK1	Ubiquitylation	K251	-0.047	-1.236	_WK(gl)PGSLASHVK_
CDK1	Ubiquitylation	K280	0.179	-1.210	_MLIYDPAK(gl)R_
COL6A1	Ubiquitylation	K121	-0.573	0.917	_SSVDAVK(gl)YFGK_
COL6A1	Ubiquitylation	K135		1.185	_GTYTDCAIKK(gl)_
COL6A2	Ubiquitylation	K120		0.009	_ASFIK(gl)NLQGISSFR_
COL6A2	Ubiquitylation	K197		-0.738	_LFAVAPNQNLK(gl)EQGLR_
COL6A2	Ubiquitylation	K851		-0.451	_LGEQNFHK(gl)AR_
CREB1	Phosphorylation	S271	-0.979	-1.450	_TAPTSTIAPGVVM(ox)ASS(ph)PALPTQPAEEAAR_
CREB1	Ubiquitylation	K333	1.343		_ALK(gl)DLYCHK_
FGFR1	Ubiquitylation	K510	1.047	-0.221	_VTK(gl)VAVK_
FYN	Ubiquitylation	K13	0.286		_DKEATK(gl)LTEER_
FYN	Phosphorylation	S21	0.373	0.731	_DGS(ph)LNQSSGYR_
FYN	Ubiquitylation	K259		0.921	_LTDLSVK(gl)TK_
FYN	Ubiquitylation	K261	0.099		_LTDLSVKTK(gl)_
FYN	Ubiquitylation	K273	6.025		_SLCLEKK(gl)_
FYN	Ubiquitylation	K275	-0.521		_ESLQLIK(gl)R_
GRB2	Ubiquitylation	K10	0.146		_YDFK(gl)ATADDELSFK_
GRB2	Ubiquitylation	K20	-0.078		_ATADDELSFK(gl)R_
GRB2	Ubiquitylation	K69	-0.362	0.641	_AK(gl)AEEMLSK_
GRB2	Ubiquitylation	K76	0.754		_AEEMLSK(gl)QR_
GRB2	Ubiquitylation	K109	0.381	-0.002	_FGNDVQHFK(gl)VLR_
HRAS	Ubiquitylation	K170	-1.005		_K(gl)LNPPDESGPGCMSCK_
KRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
KRAS	Ubiquitylation	K235	0.591	0.087	_TVDTK(gl)QAQDLAR_
KRAS	Ubiquitylation	K254	-0.450	-0.156	_SYGIPFIETSAK(gl)TR_
MAP2K1	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K1	Phosphorylation	S385		0.066	_RSDAEEVDFAGWLCSTIGLNQPS(ph)TPTHAAGV_
MAP2K1	Phosphorylation	T386		0.377	_RSDAEEVDFAGWLCSTIGLNQPST(ph)PTHAAGV_
MAP2K2	Phosphorylation	S23	0.873	0.258	_RKPVLPALTINPTIAEGPS(ph)PTSEGASEANLVDLQK_
MAP2K2	Phosphorylation	T25		0.439	_RKPVLPALTINPTIAEGPSPT(ph)SEGASEANLVDLQK_
MAP2K2	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K2	Phosphorylation	S293		-0.361	_ELEAIFGRPVVDGEEGEPHS(ph)ISPR_
MAP2K2	Phosphorylation	S295	-0.234	0.026	_ELEAIFGRPVVDGEEGEPHSIS(ph)PR_
MAP2K2	Phosphorylation	T394	0.570	0.158	_LNQPGT(ph)PTR_
MAPK3	Phosphorylation	Y204	-0.807	-2.487	_IADPEHDHTGFLTEY(ph)VATR_
MAPK3	Ubiquitylation	K289		-0.608	_NYLQSLPSKTK(gl)_
NRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
RAF1	Phosphorylation	S29	0.028	-0.571	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	T31	0.028	-0.669	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	S244		0.053	_YSTPHAFTFNTSS(ph)PSSEGSLSQR_
RAF1	Phosphorylation	S259	-0.069	0.054	_STS(ph)TPNVHM(ox)VSTTLPVDSR_
RAF1	Phosphorylation	S301		-0.651	_SHSESASPSALSSSPNNLS(ph)PTGWSQPK_
RAF1	Phosphorylation	T303		-0.664	_SHSESASPSALSSSPNNLSPT(ph)GWSQPK_
RAF1	Phosphorylation	S497		-0.449	_SRWS(ph)GSQQVEQPTGSVLWMAPEVIR_
RAF1	Phosphorylation	S621	0.212	0.271	_SAS(ph)EPSLHR_
RAF1	Phosphorylation	S642	-0.197	0.463	_AAHTEDINACTLTTS(ph)PR_
SOS1	Phosphorylation	S1082	0.278		_IPESETESTASAPNS(ph)PR_
SOS1	Phosphorylation	S1166	0.097	-0.094	_RPESAPAES(ph)SPSK_
SPTAN1	Ubiquitylation	K864	-0.012		_GNAMVEEGHFAAEDVKAK(gl)_
SPTAN1	Phosphorylation	S1029	1.169	1.417	_LDPAQS(ph)ASRENLLEEQGSIALR_
SPTAN1	Phosphorylation	S1031	1.169	1.397	_LDPAQSAS(ph)RENLLEEQGSIALR_
SPTAN1	Ubiquitylation	K1187	0.393	-0.095	_DETDSK(gl)TASPWK_
SPTAN1	Ubiquitylation	K1193	0.677	0.204	_TASPWK(gl)SAR_
SPTAN1	Phosphorylation	S1217	0.717	0.823	_WRS(ph)LQQLAEER_
SPTAN1	Ubiquitylation	K2057	1.535	0.543	_HVQSK(gl)AIEAR_
SPTB	Ubiquitylation	K105	-0.685		_LPKPTK(gl)GR_
SPTB	Ubiquitylation	K593	-1.044	-0.240	_GVNASAQK(gl)FATDGEGYKPCDPQVIR_
SPTB	Ubiquitylation	K924	0.362		_QLMHSGHPSEK(gl)EIK_
SPTB	Ubiquitylation	K1532	-0.807		_NQTLQK(gl)EIQGHQPR_
SPTB	Phosphorylation	S2102	-0.534	-0.677	_RPPS(ph)PEPSTK_
SPTB	Phosphorylation	S2114		0.318	_TS(ph)PVSLWSR_
SPTB	Ubiquitylation	K2177	0.394		_AK(gl)TALPAQSAATLPAR_
SPTB	Ubiquitylation	K2269	1.563	1.748	_EAVCEVALDYK(gl)K_
SPTB	Ubiquitylation	K2270	1.484	1.748	_EAVCEVALDYKK(gl)_
SPTB	Phosphorylation	T2317	-0.391		_HEVSAST(ph)QSTPASSR_
SPTB	Phosphorylation	S2319	0.406	0.012	_HEVSASTQS(ph)TPASSR_
SPTB	Phosphorylation	T2320	0.156	-0.264	_HEVSASTQST(ph)PASSR_
SPTB	Phosphorylation	T2335		-0.213	_AQTLPTSVVT(ph)ITSESSPGKR_
SPTB	Phosphorylation	S2338		-0.151	_AQTLPTSVVTITS(ph)ESSPGK_
SPTB	Phosphorylation	S2340	-0.260	-0.175	_AQTLPTSVVTITSES(ph)SPGKR_
SPTB	Phosphorylation	S2341	-0.329	-0.373	_AQTLPTSVVTITSESS(ph)PGK_
SPTB	Ubiquitylation	K2344	1.728	-0.691	_AQTLPTSVVTITSESSPGK(gl)R_
SPTB	Ubiquitylation	K2362	1.856		_FSLFGK(gl)K_
SPTB	Ubiquitylation	K2363	1.856		_FSLFGK(gl)K_
SPTBN1	Ubiquitylation	K105	-0.685		_LPKPTK(gl)GR_
SPTBN1	Ubiquitylation	K593	-1.044	-0.240	_GVNASAQK(gl)FATDGEGYKPCDPQVIR_
SPTBN1	Ubiquitylation	K924	0.362		_QLMHSGHPSEK(gl)EIK_
SPTBN1	Ubiquitylation	K1532	-0.807		_NQTLQK(gl)EIQGHQPR_
SPTBN1	Phosphorylation	S2102	-0.534	-0.677	_RPPS(ph)PEPSTK_
SPTBN1	Ubiquitylation	K2177	0.394		_AK(gl)TALPAQSAATLPAR_
SPTBN1	Ubiquitylation	K2269	1.563	1.748	_EAVCEVALDYK(gl)K_
SPTBN1	Ubiquitylation	K2270	1.484	1.748	_EAVCEVALDYKK(gl)_
SPTBN1	Phosphorylation	T2317	-0.391		_HEVSAST(ph)QSTPASSR_
SPTBN1	Phosphorylation	S2319	0.406	0.012	_HEVSASTQS(ph)TPASSR_
SPTBN1	Phosphorylation	T2320	0.156	-0.264	_HEVSASTQST(ph)PASSR_
SPTBN1	Phosphorylation	T2335		-0.213	_AQTLPTSVVT(ph)ITSESSPGKR_
SPTBN1	Phosphorylation	S2338		-0.151	_AQTLPTSVVTITS(ph)ESSPGK_
SPTBN1	Phosphorylation	S2340	-0.260	-0.175	_AQTLPTSVVTITSES(ph)SPGKR_
SPTBN1	Phosphorylation	S2341	-0.329	-0.373	_AQTLPTSVVTITSESS(ph)PGK_
SPTBN1	Ubiquitylation	K2344	1.728	-0.691	_AQTLPTSVVTITSESSPGK(gl)R_
SPTBN1	Ubiquitylation	K2362	1.856		_FSLFGK(gl)K_
SPTBN1	Ubiquitylation	K2363	1.856		_FSLFGK(gl)K_
SPTBN2	Ubiquitylation	K2304	1.539		_LGLQDGK(gl)EYLFQAK_
SRC	Phosphorylation	S17	-0.604	-0.689	_S(ph)LEPAENVHGAGGGAFPASQTPSKPASADGHR_
SRC	Phosphorylation	S75	0.060	0.331	_LFGGFNSSDTVTS(ph)PQR_
YWHAB	Ubiquitylation	K11	1.057	1.322	_(ac)TMDKSELVQK(gl)AK_
YWHAB	Ubiquitylation	K13	0.060	0.388	_AK(gl)LAEQAER_
YWHAB	Ubiquitylation	K70	0.558	-0.175	_VISSIEQK(gl)TER_
YWHAB	Ubiquitylation	K140		0.531	_YLSEVASGDNK(gl)QTTVSNSQQAYQEAFEISKK_
YWHAB	Ubiquitylation	K159	0.300		_QTTVSNSQQAYQEAFEISK(gl)K_
YWHAB	Ubiquitylation	K160	-0.439	-0.371	_K(gl)EMQPTHPIR_