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Query: SPTBN2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SPTBN2 1 2.110 0.870 0.420 0.258 0.313

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SPTBN2 Ubiquitylation K2304 1.539 _LGLQDGK(gl)EYLFQAK_

Background Information for SPTBN2:


Pubmed-SPTBN2 »
Uniprot-SPTBN2 »
Biogrid-SPTBN2 »
ProteomicsDB-SPTBN2 »

Tumorportal-SPTBN2 »
COSMIC-SPTBN2 »
GenomeRNAi-SPTBN2 »
Genecards-SPTBN2


Protein-protein Interactions for SPTBN2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ASF1A Cat. description Hein, Mann, Cell 2015
Category members IP bait ATAD2 Cat. description Hein, Mann, Cell 2015
Category members IP bait AURKB Cat. description Hein, Mann, Cell 2015
Category members IP bait BOD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CALML3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNA Cat. description Hein, Mann, Cell 2015
Category members IP bait IQGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO18A Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait SGTB Cat. description Hein, Mann, Cell 2015
Category members IP bait SORT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNPO Cat. description Hein, Mann, Cell 2015


Protein Domains in SPTBN2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Spectrin_repeat IPR002017 2.4
Category members Spectrin/alpha-actinin IPR018159 1.6
Category members CH-domain IPR001715 0.63
Category members PH_domain IPR001849 0.14
Category members CAMSAP_CH IPR022613 0.13
Category members Spectrin_bsu IPR016343 0.04
Category members PH_dom-spectrin-type IPR001605 0


Protein complexes (CORUM database) featuring SPTBN2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SPTBN2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0003779 actin binding Database 5.41
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_1075 REACTOME_L1CAM_INTERACTIONS 0 1.32
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members Pathway Pathway_673 REACTOME_AXON_GUIDANCE 0 1.06
Category members Pathway Pathway_1265 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION 0 0.6
Category members GO Category GO:0008091 spectrin Database 0.43
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members GO Category GO:0021692 cerebellar Purkinje cell layer morphogenesis Database 0.23
Category members GO Category GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II Database 0.13
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members GO Category GO:0008219 cell death Database 0.08
Category members GO Category GO:0035264 multicellular organism growth Database 0.04
Category members Pathway Pathway_1010 REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH 0 0
Category members Pathway Pathway_1287 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS 0 0
Category members GO Category GO:0005200 structural constituent of cytoskeleton Database 0
Category members GO Category GO:0005543 phospholipid binding Database 0
Category members GO Category GO:0007416 synapse assembly Database 0
Category members GO Category GO:0030534 adult behavior Database 0
Category members GO Category GO:0043025 neuronal cell body Database 0
Category members GO Category GO:0051693 actin filament capping Database 0


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