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PID_LYSOPHOSPHOLIPID_PATHWAY
(Pathway_237)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
JUN 3 -0.930 0.930 -0.126
GSK3B 2 1.020 -0.870 -1.128 1.091
GNAI3 1 0.750 -0.890
GNAI3 1 0.750 -0.890 0.217 -0.334 -0.374
GNAO1 1 1.200 -1.320
GNAO1 1 1.200 -1.320 0.217 -0.334 -0.374
GNA11 1 2.030 -1.240 0.953 0.764 0.108
GNA13 1 0.350 -0.930 0.375 0.243
PLCG1 1 -0.170 0.000
PLD2 1 -0.390 -0.250
ADCY3 1 -0.850 1.180
LYN 1 -1.790 3.770
LYN 1 -1.790 3.770
PIK3CB 0 -1.390 2.350
PIK3CB 0 -0.710 1.450
GNAI1 0 -0.580 0.990
GNAI2 0 0.190 -0.520
GNAL 0 1.660 -1.170
GNAS 0 0.840 -0.750
GNAT1 0 -0.110 -0.270
GNAT2 0 0.140 -0.880
GNAT3 0 1.110 -0.500
RHOA 0 -0.510 1.370 -0.485 0.532 0.279
ARHGEF1 0 -0.170 0.400
GNB1 0 -0.700 0.650 0.713 0.504 0.538
GNB3 0 -1.020 1.280 0.713 0.504 0.538
MAGI3 0 1.510 -0.840
MAGI3 0 1.510 -0.840 0.696 0.967
PXN 0 1.020 -0.760
NFKB1 0 0.720 -0.810
GAB1 0 1.950 -1.110
ADCY7 0
GNAI1 0 -0.580 0.990 0.116 -0.747
GNAZ 0 -0.020 -0.560
RAC1 0 -0.580 1.580 0.486 -0.364 -0.568
AKT1 0 -0.050 0.700
AKT1 0 0.860 -0.040
PIK3R1 0 1.910 -1.220 -0.441 0.147
EGFR 0 -0.580 0.520 0.513 0.090
GNA14 0 1.610 -0.450 0.492
GNAQ 0 0.140 -0.310 0.052 0.449
TIAM1 0 -0.620 0.220
ADCY9 0 -0.910 0.930
PRKCD 0 0.250 0.070 0.578 0.427
CASP3 0 0.570 -0.390
CRK 0 -0.790 0.230
RELA 0 -1.130 1.600 0.793
ADCY6 0 -0.720 0.740
HRAS 0 1.470 -0.520
PRKD1 0 1.050 0.130
PRKD1 0 1.050 0.130
PRKD1 0 1.050 0.130
MAPT 0 -0.190 0.150
SRC 0 0.050 0.470 -0.031

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ADCY3 Ubiquitylation K406 -0.885 _TK(gl)TGVDMR_
ADCY3 Ubiquitylation K628 0.051 _YSVEK(gl)EK_
ADCY3 Ubiquitylation K879 0.818 2.820 _IEVHDQK(gl)ER_
ADCY3 Ubiquitylation K1047 -1.036 _IGMNK(gl)GGVLAGVIGAR_
ADCY6 Phosphorylation S54 -1.434 -1.374 _DAEPPS(ph)PTPAGPPR_
ADCY6 Ubiquitylation K80 0.473 0.937 _GK(gl)ELGLR_
ADCY6 Ubiquitylation K568 1.007 0.799 _AMLAK(gl)LQR_
ADCY6 Phosphorylation S576 -0.020 _ANS(ph)MEGLMPR_
ADCY7 Ubiquitylation K477 0.660 _GDAALK(gl)MR_
ADCY9 Ubiquitylation K35 0.400 _INPK(gl)QLSSNSHPK_
ADCY9 Ubiquitylation K564 0.874 0.253 _LGQSVVADQLK(gl)GLK_
ADCY9 Ubiquitylation K622 0.176 0.287 _GQGTASSGNVSDLAQTVK(gl)TFDNLK_
ADCY9 Ubiquitylation K628 0.266 _TFDNLK(gl)TCPSCGITFAPK_
ADCY9 Ubiquitylation K699 1.085 _LTNSQTSLCEILQEK(gl)GR_
ADCY9 Ubiquitylation K1218 1.351 1.067 _VLSK(gl)MGYDFDYR_
AKT1 Phosphorylation S124 0.252 0.311 _SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1 Phosphorylation S126 -0.241 _SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1 Ubiquitylation K301 0.988 _EGIK(gl)DGATMK_
ARHGEF1 Phosphorylation S863 -0.276 -0.053 _DGDGVPGGGPLS(ph)PAR_
CASP3 Ubiquitylation K11 -0.053 -0.687 _(ac)MENTENSVDSK(gl)SIK_
CASP3 Ubiquitylation K14 -0.455 -0.687 _SIK(gl)NLEPK_
CASP3 Ubiquitylation K57 -0.304 -1.817 _NFHK(gl)STGMTSR_
CASP3 Ubiquitylation K82 -0.268 -0.605 _NLK(gl)YEVR_
CRK Phosphorylation S40 0.533 0.363 _DS(ph)STSPGDYVLSVSENSR_
CRK Phosphorylation S41 1.065 0.801 _DSS(ph)TSPGDYVLSVSENSR_
EGFR Phosphorylation T693 0.486 -0.139 _ELVEPLT(ph)PSGEAPNQALLR_
EGFR Phosphorylation S991 -0.041 _MHLPS(ph)PTDSNFYR_
GAB1 Phosphorylation S266 0.756 0.551 _SYS(ph)HDVLPK_
GAB1 Phosphorylation S367 0.230 0.176 _TAS(ph)DTDSSYCIPTAGMS(ph)PSR_
GAB1 Phosphorylation T369 -0.352 _TASDT(ph)DSSYCIPTAGMS(ph)PSR_
GAB1 Phosphorylation S381 -0.481 0.139 _TASDTDSSYCIPTAGM(ox)S(ph)PSR_
GAB1 Phosphorylation S401 0.266 0.788 _DAS(ph)SQDCYDIPR_
GAB1 Phosphorylation S402 0.328 0.633 _DASS(ph)QDCYDIPR_
GAB1 Phosphorylation S419 0.540 _SSS(ph)LEGFHNHFK_
GNA11 Ubiquitylation K16 0.347 _(ac)TLESMMACCLSDEVK(gl)ESKR_
GNA11 Ubiquitylation K27 0.292 1.135 _RINAEIEK(gl)QLR_
GNA11 Ubiquitylation K102 0.502 0.512 _ILYK(gl)YEQNK_
GNA13 Ubiquitylation K36 0.742 1.351 _EIDK(gl)CLSR_
GNA13 Ubiquitylation K66 1.633 _STFLK(gl)QMR_
GNAI1 Ubiquitylation K53 -1.168 -0.413 _LLLLGAGESGK(gl)STIVK_
GNAI1 Ubiquitylation K92 0.873 0.567 _LK(gl)IDFGDSAR_
GNAI2 Ubiquitylation K53 -1.168 -0.413 _LLLLGAGESGK(gl)STIVK_
GNAI3 Ubiquitylation K29 0.529 -0.094 _NLREDGEK(gl)AAK_
GNAI3 Ubiquitylation K53 -1.168 -0.413 _LLLLGAGESGK(gl)STIVK_
GNAI3 Ubiquitylation K92 1.569 _LK(gl)IDFGEAAR_
GNAI3 Ubiquitylation K349 -0.221 -0.339 _NNLK(gl)ECGLY_
GNAL Ubiquitylation K53 -1.168 -0.413 _LLLLGAGESGK(gl)STIVK_
GNAO1 Ubiquitylation K29 0.529 -0.094 _NLREDGEK(gl)AAK_
GNAO1 Ubiquitylation K53 -1.168 -0.413 _LLLLGAGESGK(gl)STIVK_
GNAO1 Ubiquitylation K92 1.569 _LK(gl)IDFGEAAR_
GNAO1 Ubiquitylation K349 -0.221 -0.339 _NNLK(gl)ECGLY_
GNAQ Ubiquitylation K16 0.245 _TLESIMACCLSEEAK(gl)EAR_
GNAQ Ubiquitylation K102 -0.299 _IPYK(gl)YEHNK_
GNAS Ubiquitylation K53 -1.168 -0.413 _LLLLGAGESGK(gl)STIVK_
GNAT1 Ubiquitylation K53 -1.168 -0.413 _LLLLGAGESGK(gl)STIVK_
GNAT2 Ubiquitylation K53 -1.168 -0.413 _LLLLGAGESGK(gl)STIVK_
GNAT3 Ubiquitylation K53 -1.168 -0.413 _LLLLGAGESGK(gl)STIVK_
GNAZ Ubiquitylation K51 0.481 -0.051 _STIVK(gl)QMK_
GNAZ Ubiquitylation K189 0.945 _DMTTGIVENK(gl)FTFK_
GNB1 Ubiquitylation K23 -0.282 _K(gl)ACADATLSQITNNIDPVGR_
GNB1 Ubiquitylation K209 -0.296 -0.249 _LFVSGACDASAK(gl)LWDVR_
GNB3 Ubiquitylation K23 -0.282 _K(gl)ACADATLSQITNNIDPVGR_
GNB3 Ubiquitylation K209 -0.296 -0.249 _LFVSGACDASAK(gl)LWDVR_
GSK3B Phosphorylation S9 -0.483 0.010 _TTS(ph)FAESCKPVQQPSAFGSMK_
GSK3B Ubiquitylation K85 -0.204 _LCDSGELVAIK(gl)K_
GSK3B Ubiquitylation K86 -0.204 _LCDSGELVAIK(gl)K_
GSK3B Phosphorylation S215 0.296 0.477 _GEPNVS(ph)YICSR_
GSK3B Phosphorylation Y216 0.356 0.376 _GEPNVSY(ph)ICSR_
GSK3B Phosphorylation T390 2.800 2.527 _IQAAAST(ph)PTNATAASDANTGDR_
HRAS Ubiquitylation K170 -1.005 _K(gl)LNPPDESGPGCMSCK_
JUN Phosphorylation S58 -0.167 -1.247 _AKNS(ph)DLLTSPDVGLLK_
JUN Phosphorylation T62 2.545 1.674 _NSDLLT(ph)SPDVGLLK_
JUN Phosphorylation S63 2.030 1.458 _NSDLLTS(ph)PDVGLLK_
JUN Ubiquitylation K70 9.213 _NSDLLTSPDVGLLK(gl)_
JUN Phosphorylation S73 1.499 0.845 _LAS(ph)PELER_
JUN Phosphorylation S243 -0.642 -1.399 _LQALKEEPQTVPEMPGETPPLS(ph)PIDMESQER_
JUN Ubiquitylation K309 1.034 0.155 _EQVAQLK(gl)QK_
LYN Ubiquitylation K20 -0.592 _GKDSLSDDGVDLK(gl)TQPVR_
LYN Ubiquitylation K40 0.100 _DPTSNK(gl)QQRPVPESQLLPGQR_
LYN Phosphorylation S104 0.944 0.841 _DSLS(ph)DDGVDLK_
LYN Ubiquitylation K213 0.441 _HYQK(gl)QADGLCR_
LYN Ubiquitylation K477 -0.191 _VENCPDELYDIMK(gl)MCWK_
MAGI3 Phosphorylation S722 -0.403 _S(ph)GSPKLDPSEVYLK_
MAGI3 Phosphorylation S724 -0.403 _SGS(ph)PKLDPSEVYLK_
MAPT Phosphorylation S437 -2.106 -1.602 _HPTPGSSDPLIQPSSPAVCPEPPS(ph)SPK_
MAPT Phosphorylation S438 -2.106 -1.602 _HPTPGSSDPLIQPSSPAVCPEPPS(ph)SPK_
MAPT Phosphorylation S516 -0.589 _SGYSS(ph)PGSPGTPGSR_
MAPT Phosphorylation S519 -0.792 -1.278 _SGYSSPGS(ph)PGTPGSR_
MAPT Phosphorylation T548 -0.976 -0.803 _VAVVRT(ph)PPKS(ph)PSSAK_
MAPT Phosphorylation S552 -0.811 -0.801 _VAVVRT(ph)PPKS(ph)PSSAK_
MAPT Phosphorylation S717 -0.091 -0.193 _SPVVS(ph)GDTSPR_
MAPT Phosphorylation T720 -0.287 0.006 _SPVVSGDT(ph)SPR_
MAPT Phosphorylation S721 -0.091 -0.203 _SPVVSGDTS(ph)PR_
MAPT Phosphorylation S729 -0.160 _HLSNVS(ph)STGSIDMVDSPQLATLADEVSASLAK_
MAPT Phosphorylation S733 -0.413 -0.151 _HLSNVSSTGS(ph)IDMVDSPQLATLADEVSASLAK_
NFKB1 Phosphorylation S907 -0.025 0.113 _TTSQAHSLPLS(ph)PASTR_
PIK3CB Ubiquitylation K1044 0.990 _SEEEALKQFKQK(gl)_
PLCG1 Ubiquitylation K300 8.031 _DLK(gl)NMLSQVNYR_
PLCG1 Ubiquitylation K348 -0.219 _SLMYSAQK(gl)TMDLPFLEASTLR_
PLCG1 Ubiquitylation K552 -0.355 _NMAQYFK(gl)K_
PLCG1 Ubiquitylation K553 -0.355 _NMAQYFK(gl)K_
PLCG1 Ubiquitylation K1063 0.864 0.355 _LTEGK(gl)IMER_
PLCG1 Phosphorylation S1370 0.475 0.515 _AREGS(ph)FESR_
PLD2 Ubiquitylation K80 2.298 _YTSGSK(gl)VGTCTLYSVR_
PRKCD Ubiquitylation K138 -0.141 _SEDEAK(gl)FPTMNR_
PRKCD Ubiquitylation K222 0.185 0.658 _DTIFQK(gl)ER_
PRKCD Phosphorylation S302 -0.240 -0.222 _S(ph)DSASSEPVGIYQGFEK_
PRKCD Phosphorylation S304 0.378 0.289 _RSDS(ph)ASSEPVGIYQGFEK_
PRKCD Phosphorylation S506 -0.213 0.200 _AS(ph)TFCGTPDYIAPEILQGLK_
PRKCD Phosphorylation T507 -0.149 0.240 _AS(ph)TFCGTPDYIAPEILQGLK_
PRKCD Ubiquitylation K641 -2.000 _DYSNFDQEFLNEK(gl)AR_
PRKCD Phosphorylation S645 0.577 0.832 _ARLS(ph)YSDK_
PRKCD Phosphorylation S647 0.886 0.853 _ARLSYS(ph)DK_
PRKD1 Phosphorylation S207 0.941 1.048 _RLS(ph)NVSLTGVSTIR_
PRKD1 Phosphorylation T219 -0.068 -0.162 _T(ph)SSAELSTSAPDEPLLQK_
PRKD1 Phosphorylation S221 -0.662 -0.500 _TSS(ph)AELSTSAPDEPLLQK_
PRKD1 Phosphorylation S225 -0.970 -0.919 _TSSAELSTS(ph)APDEPLLSPVSPGFEQK_
PRKD1 Phosphorylation S236 -0.132 _TSSAELSTSAPDEPLLSPVS(ph)PGFEQK_
PRKD1 Phosphorylation S251 0.474 0.751 _SNS(ph)QSYIGRPIHLDK_
PRKD1 Phosphorylation S399 0.023 0.162 _TIS(ph)PSTSNNIPLMR_
PRKD1 Ubiquitylation K730 1.177 _IIGEK(gl)SFR_
PRKD1 Phosphorylation S744 -0.226 -0.287 _S(ph)VVGTPAYLAPEVLR_
PXN Phosphorylation S85 -0.156 0.192 _FIHQQPQSSS(ph)PVYGSSAK_
PXN Phosphorylation T136 1.322 _SAEPSPTVMST(ph)SLGSNLSELDR_
PXN Phosphorylation S140 -0.291 -0.948 _SAEPSPTVM(ox)STSLGS(ph)NLSELDR_
PXN Phosphorylation S302 -0.167 _S(ph)SPGGQDEGGFMAQGK_
PXN Phosphorylation S303 -0.167 _S(ph)SPGGQDEGGFMAQGK_
PXN Phosphorylation S322 -1.234 _TGSSS(ph)PPGGPPKPGSQLDSMLGSLQSDLNK_
RAC1 Ubiquitylation K115 -1.745 -0.215 _AK(gl)WYPEVR_
RAC1 Ubiquitylation K142 0.492 _LDLRDDK(gl)DTIEK_
RAC1 Ubiquitylation K152 0.099 -0.292 _K(gl)LTPITYPQGLAMAK_
RAC1 Ubiquitylation K166 -0.981 -0.655 _LTPITYPQGLAMAK(gl)EIGAVK_
RAC1 Ubiquitylation K172 1.026 0.412 _EIGAVK(gl)YLECSALTQR_
RAC1 Ubiquitylation K185 -0.113 0.578 _GLK(gl)TVFDEAIR_
RAC1 Ubiquitylation K202 -1.379 -1.447 _AVLCPPPVK(gl)KR_
RAC1 Ubiquitylation K203 -1.708 -1.447 _AVLCPPPVKK(gl)_
RHOA Ubiquitylation K6 0.708 _K(gl)KLVIVGDGACGK_
RHOA Ubiquitylation K7 0.708 _K(gl)KLVIVGDGACGK_
RHOA Ubiquitylation K118 -0.408 _HFCPNVPIILVGNK(gl)K_
RHOA Ubiquitylation K119 -0.408 _HFCPNVPIILVGNK(gl)K_
RHOA Ubiquitylation K135 -0.528 -0.796 _MK(gl)QEPVKPEEGRDMANR_
RHOA Ubiquitylation K162 0.345 0.453 _IGAFGYMECSAK(gl)TK_
SRC Phosphorylation S17 -0.604 -0.689 _S(ph)LEPAENVHGAGGGAFPASQTPSKPASADGHR_
SRC Phosphorylation S75 0.060 0.331 _LFGGFNSSDTVTS(ph)PQR_
TIAM1 Phosphorylation S231 0.453 0.331 _ANS(ph)LGDLYAQK_
TIAM1 Phosphorylation T1405 0.267 _T(ph)ESLPSSQQYVPFGGK_
TIAM1 Phosphorylation S1407 -0.862 -0.252 _TES(ph)LPSSQQYVPFGGK_


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