bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: ARHGEF1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ARHGEF1 0 0.071 -0.170 0.400

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ARHGEF1 Phosphorylation S863 -0.276 -0.053 _DGDGVPGGGPLS(ph)PAR_

Background Information for ARHGEF1:


Pubmed-ARHGEF1 »
Uniprot-ARHGEF1 »
Biogrid-ARHGEF1 »
ProteomicsDB-ARHGEF1 »

Tumorportal-ARHGEF1 »
COSMIC-ARHGEF1 »
GenomeRNAi-ARHGEF1 »
Genecards-ARHGEF1


Protein-protein Interactions for ARHGEF1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCNJL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSMC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RHOA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RHOC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait THBS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ARHGEF1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PH_domain IPR001849 0.14
Category members Regulat_G_prot_signal_superfam IPR016137 0.05
Category members DH-domain IPR000219 0.05
Category members RGS-like_dom IPR015212 0


Protein complexes (CORUM database) featuring ARHGEF1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3177 GNA14-p115RhoGEF complex Database 0


Categories featuring ARHGEF1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_221 REACTOME_SIGNALLING_BY_NGF 0 2.14
Category members Pathway Pathway_243 REACTOME_GPCR_DOWNSTREAM_SIGNALING 0 1.27
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_240 BIOCARTA_PAR1_PATHWAY 0 1.11
Category members Pathway Pathway_237 PID_LYSOPHOSPHOLIPID_PATHWAY 0 1.09
Category members Pathway Pathway_256 REACTOME_SIGNALING_BY_GPCR 0 0.83
Category members GO Category GO:0048011 neurotrophin TRK receptor signaling pathway Database 0.63
Category members Pathway Pathway_677 BIOCARTA_MYOSIN_PATHWAY 0 0.53
Category members Pathway Pathway_667 BIOCARTA_RHO_PATHWAY 0 0.3
Category members Pathway Pathway_739 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING 0 0.23
Category members GO Category GO:0005096 GTPase activator activity Database 0.19
Category members Pathway Pathway_428 PID_THROMBIN_PAR1_PATHWAY 0 0.18
Category members GO Category GO:0035023 regulation of Rho protein signal transduction Database 0.17
Category members Pathway Pathway_1172 PID_RHOA_REG_PATHWAY 0 0.09
Category members Pathway Pathway_580 KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 0 0.08
Category members GO Category GO:0005089 Rho guanyl-nucleotide exchange factor activity Database 0.08
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0038032 termination of G-protein coupled receptor signaling pathway Database 0.05
Category members Pathway Pathway_160 KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION 0 0.01
Category members Pathway Pathway_430 PID_TXA2PATHWAY 0 0
Category members Pathway Pathway_623 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS 0 0
Category members GO Category GO:0007266 Rho protein signal transduction Database 0
Category members GO Category GO:0050770 regulation of axonogenesis Database 0
Category members GO Category GO:0050771 negative regulation of axonogenesis Database 0


.

© Copyright Svejstrup Laboratory 2015