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Query: PLD2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PLD2 1 2.048 -0.390 -0.250

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PLD2 Ubiquitylation K80 2.298 _YTSGSK(gl)VGTCTLYSVR_

Background Information for PLD2:


Pubmed-PLD2 »
Uniprot-PLD2 »
Biogrid-PLD2 »
ProteomicsDB-PLD2 »

Tumorportal-PLD2 »
COSMIC-PLD2 »
GenomeRNAi-PLD2 »
Genecards-PLD2


Protein-protein Interactions for PLD2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CACNG5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC107 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDH5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDH8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK5RAP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHRM3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CRYL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DNAJC7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR156 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HAVCR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPC24 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFRSF19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBB Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PLD2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Phox IPR001683 0.24
Category members PH_domain IPR001849 0.14
Category members PLipase_D_euk IPR016555 0.11
Category members PLipase_D/transphosphatidylase IPR001736 0


Protein complexes (CORUM database) featuring PLD2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PLD2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members Pathway Pathway_670 PID_ARF_3PATHWAY 0 3.15
Category members Pathway Pathway_724 PID_MTOR_4PATHWAY 0 2
Category members Pathway Pathway_579 PID_ERBB1_DOWNSTREAM_PATHWAY 0 1.97
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members Pathway Pathway_666 KEGG_ENDOCYTOSIS 0 1.25
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_237 PID_LYSOPHOSPHOLIPID_PATHWAY 0 1.09
Category members Pathway Pathway_295 PID_ARF6_TRAFFICKING_PATHWAY 0 0.9
Category members Pathway Pathway_662 PID_IL8_CXCR2_PATHWAY 0 0.62
Category members GO Category GO:0035091 phosphatidylinositol binding Database 0.62
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis Database 0.33
Category members Pathway Pathway_514 ST_GAQ_PATHWAY 0 0.17
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members Pathway Pathway_499 KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS 0 0.1
Category members Pathway Pathway_296 PID_ARF6_DOWNSTREAM_PATHWAY 0 0.08
Category members Pathway Pathway_405 PID_ALPHA_SYNUCLEIN_PATHWAY 0 0.08
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members Pathway Pathway_434 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY 0 0.04
Category members Pathway Pathway_100 REACTOME_PHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_161 REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS 0 0
Category members Pathway Pathway_257 KEGG_GNRH_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_276 KEGG_GLYCEROPHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_482 REACTOME_SYNTHESIS_OF_PA 0 0
Category members Pathway Pathway_497 KEGG_ETHER_LIPID_METABOLISM 0 0
Category members Pathway Pathway_500 PID_FCER1_PATHWAY 0 0
Category members Pathway Pathway_658 ST_GA13_PATHWAY 0 0
Category members Pathway Pathway_668 PID_RHOA_PATHWAY 0 0
Category members Pathway Pathway_725 ST_GA12_PATHWAY 0 0
Category members GO Category GO:0002031 G-protein coupled receptor internalization Database 0
Category members GO Category GO:0004630 phospholipase D activity Database 0
Category members GO Category GO:0006644 phospholipid metabolic process Database 0
Category members GO Category GO:0006654 phosphatidic acid biosynthetic process Database 0
Category members GO Category GO:0006655 phosphatidylglycerol biosynthetic process Database 0
Category members GO Category GO:0006898 receptor-mediated endocytosis Database 0
Category members GO Category GO:0007010 cytoskeleton organization Database 0
Category members GO Category GO:0007154 cell communication Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0016042 lipid catabolic process Database 0
Category members GO Category GO:0031526 brush border membrane Database 0
Category members GO Category GO:0046474 glycerophospholipid biosynthetic process Database 0
Category members GO Category GO:0070290 NAPE-specific phospholipase D activity Database 0


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