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Query: GNAT2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GNAT2 0 -0.885 0.140 -0.880
GNAT2 0 -0.885 0.140 -0.880 -0.166 -0.094 0.032 0.420 0.504

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GNAT2 Ubiquitylation K53 -1.168 -0.413 _LLLLGAGESGK(gl)STIVK_

Background Information for GNAT2:





Protein-protein Interactions for GNAT2

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GNAI3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GNAT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GNG3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GNAT2

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Small_GTPase_ARF/SAR IPR006689 0.8
Category members GproteinA_insert IPR011025 0.18
Category members Gprotein_alpha_su IPR001019 0.02
Category members Gprotein_alpha_I IPR001408 0


Protein complexes (CORUM database) featuring GNAT2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GNAT2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0007186 G-protein coupled receptor signaling pathway Database 1.53
Category members Pathway Pathway_243 REACTOME_GPCR_DOWNSTREAM_SIGNALING 0 1.27
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_256 REACTOME_SIGNALING_BY_GPCR 0 0.83
Category members Pathway Pathway_263 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS 0 0.49
Category members Pathway Pathway_260 REACTOME_OPIOID_SIGNALLING 0 0.28
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members Disease phenotype Achromatopsia Achromatopsia Database 0.11
Category members GO Category GO:0031234 extrinsic to cytoplasmic side of plasma membrane Database 0.1
Category members GO Category GO:0001664 G-protein coupled receptor binding Database 0.09
Category members GO Category GO:0019001 guanyl nucleotide binding Database 0.07
Category members Disease phenotype Progressive_cone_dystrophy Progressive cone dystrophy Database 0.04
Category members GO Category GO:0031683 G-protein beta/gamma-subunit complex binding Database 0.02
Category members Pathway Pathway_1100 REACTOME_G_PROTEIN_ACTIVATION 0 0
Category members Pathway Pathway_227 REACTOME_PLC_BETA_MEDIATED_EVENTS 0 0
Category members Pathway Pathway_289 PID_CONE_PATHWAY 0 0
Category members GO Category GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste Database 0
Category members GO Category GO:0001750 photoreceptor outer segment Database 0
Category members GO Category GO:0001917 photoreceptor inner segment Database 0
Category members GO Category GO:0004871 signal transducer activity Database 0
Category members GO Category GO:0005834 heterotrimeric G-protein complex Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway Database 0
Category members GO Category GO:0007204 positive regulation of cytosolic calcium ion concentration Database 0
Category members GO Category GO:0007601 visual perception Database 0
Category members GO Category GO:0007602 phototransduction Database 0
Category members GO Category GO:0008020 G-protein coupled photoreceptor activity Database 0
Category members GO Category GO:0009642 response to light intensity Database 0
Category members GO Category GO:0042622 photoreceptor outer segment membrane Database 0
Category members GO Category GO:0046549 retinal cone cell development Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0050908 detection of light stimulus involved in visual perception Database 0


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