Results for the Category
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
(GO:0007188)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| GNAO1 | 1 | 1.200 | -1.320 | 0.217 | -0.334 | -0.374 | ||
| GNA11 | 1 | 2.030 | -1.240 | 0.953 | 0.764 | 0.108 | ||
| GNAT1 | 0 | -0.110 | -0.270 | |||||
| GNAT1 | 0 | -0.110 | -0.270 | -0.166 | -0.094 | 0.032 | 0.420 | 0.504 |
| GNAI1 | 0 | -0.580 | 0.990 | 0.116 | -0.747 | |||
| GNAZ | 0 | -0.020 | -0.560 | |||||
| GNAT2 | 0 | 0.140 | -0.880 | -0.166 | -0.094 | 0.032 | 0.420 | 0.504 |
| PRKACB | 0 | 1.740 | -1.200 | -1.064 | ||||
| PRKACB | 0 | 1.740 | -1.200 | -1.005 | -0.697 | 0.234 | 0.487 | |
| GNA14 | 0 | 1.610 | -0.450 | 0.492 | ||||
| WASF2 | 0 | -0.540 | 0.560 | 0.137 | -0.055 | |||
| GNAT3 | 0 | 1.110 | -0.500 | -0.166 | -0.094 | 0.032 | 0.420 | 0.504 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| GNA11 | Ubiquitylation | K16 | 0.347 | _(ac)TLESMMACCLSDEVK(gl)ESKR_ | |
| GNA11 | Ubiquitylation | K27 | 0.292 | 1.135 | _RINAEIEK(gl)QLR_ |
| GNA11 | Ubiquitylation | K102 | 0.502 | 0.512 | _ILYK(gl)YEQNK_ |
| GNAI1 | Ubiquitylation | K92 | 0.873 | 0.567 | _LK(gl)IDFGDSAR_ |
| GNAO1 | Ubiquitylation | K29 | 0.529 | -0.094 | _NLREDGEK(gl)AAK_ |
| GNAO1 | Ubiquitylation | K92 | 1.569 | _LK(gl)IDFGEAAR_ | |
| GNAO1 | Ubiquitylation | K349 | -0.221 | -0.339 | _NNLK(gl)ECGLY_ |
| GNAT1 | Ubiquitylation | K17 | 0.320 | _ELEK(gl)KLK_ | |
| GNAT1 | Ubiquitylation | K18 | 0.320 | _ELEK(gl)KLK_ | |
| GNAZ | Ubiquitylation | K51 | 0.481 | -0.051 | _STIVK(gl)QMK_ |
| GNAZ | Ubiquitylation | K189 | 0.945 | _DMTTGIVENK(gl)FTFK_ | |
| PRKACB | Ubiquitylation | K30 | -0.143 | _AKEDFLKK(gl)_ | |
| PRKACB | Ubiquitylation | K93 | 0.839 | 0.714 | _QIEHTLNEK(gl)R_ |
| PRKACB | Phosphorylation | T243 | -0.835 | _T(ph)WTLCGTPEYLAPEIILSK_ | |
| PRKACB | Phosphorylation | T245 | -0.116 | -0.102 | _TWT(ph)LCGTPEYLAPEIILSK_ |
| WASF2 | Ubiquitylation | K169 | 0.110 | _MLQDTK(gl)DIMK_ | |
| WASF2 | Ubiquitylation | K216 | 1.027 | _MGQEFVESK(gl)EK_ | |
| WASF2 | Ubiquitylation | K218 | 0.488 | _MGQEFVESK(gl)EK_ | |
| WASF2 | Phosphorylation | S293 | -1.620 | _RSS(ph)VVSPSHPPPAPPLGSPPGPK_ |
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