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Query: WASF2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
WASF2 0 0.049 -0.540 0.560 0.137 -0.055

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
WASF2 Phosphorylation S293 -1.620 _RSS(ph)VVSPSHPPPAPPLGSPPGPK_
WASF2 Ubiquitylation K169 0.110 _MLQDTK(gl)DIMK_
WASF2 Ubiquitylation K216 1.027 _MGQEFVESK(gl)EK_
WASF2 Ubiquitylation K218 0.488 _MGQEFVESK(gl)EK_

Background Information for WASF2:


Pubmed-WASF2 »
Uniprot-WASF2 »
Biogrid-WASF2 »
ProteomicsDB-WASF2 »

Tumorportal-WASF2 »
COSMIC-WASF2 »
GenomeRNAi-WASF2 »
Genecards-WASF2


Protein-protein Interactions for WASF2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ABI1 Cat. description Hein, Mann, Cell 2015
Category members IP bait BAIAP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait GTF2E2 Cat. description Hein, Mann, Cell 2015
Category members IP bait ABI2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AMZ1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BAIAP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CBLC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC53 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EVL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GJB7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HOMER3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LHX4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NHSL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TIMM50 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF511 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in WASF2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WH2_dom IPR003124 0.04


Protein complexes (CORUM database) featuring WASF2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 186 Wave-2 complex Database 0.08
Category members Corum 2294 ABI1-WASF2 complex Database 0


Categories featuring WASF2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0003779 actin binding Database 5.41
Category members Pathway Pathway_292 PID_ECADHERIN_NASCENT_AJ_PATHWAY 0 2.74
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members Pathway Pathway_579 PID_ERBB1_DOWNSTREAM_PATHWAY 0 1.97
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members GO Category GO:0005769 early endosome Database 1.26
Category members Pathway Pathway_561 PID_PDGFRB_PATHWAY 0 1.18
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members Pathway Pathway_669 PID_RAC1_PATHWAY 0 0.68
Category members GO Category GO:0030032 lamellipodium assembly Database 0.66
Category members Pathway Pathway_747 KEGG_ADHERENS_JUNCTION 0 0.43
Category members GO Category GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis Database 0.33
Category members GO Category GO:0001726 ruffle Database 0.33
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0006897 endocytosis Database 0.31
Category members GO Category GO:0030048 actin filament-based movement Database 0.28
Category members GO Category GO:0006928 cellular component movement Database 0.24
Category members Pathway Pathway_499 KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS 0 0.1
Category members Pathway Pathway_580 KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 0 0.08
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members GO Category GO:0001667 ameboidal cell migration Database 0.04
Category members GO Category GO:0035855 megakaryocyte development Database 0.02
Category members Pathway Pathway_912 BIOCARTA_ACTINY_PATHWAY 0 0
Category members GO Category GO:0001525 angiogenesis Database 0
Category members GO Category GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway Database 0
Category members GO Category GO:0016601 Rac protein signal transduction Database 0


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