bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: TIAM1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TIAM1 0 1.004 -0.620 0.220

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TIAM1 Phosphorylation S231 0.453 0.331 _ANS(ph)LGDLYAQK_
TIAM1 Phosphorylation S1407 -0.862 -0.252 _TES(ph)LPSSQQYVPFGGK_
TIAM1 Phosphorylation T1405 0.267 _T(ph)ESLPSSQQYVPFGGK_

Background Information for TIAM1:


Pubmed-TIAM1 »
Uniprot-TIAM1 »
Biogrid-TIAM1 »
ProteomicsDB-TIAM1 »

Tumorportal-TIAM1 »
COSMIC-TIAM1 »
GenomeRNAi-TIAM1 »
Genecards-TIAM1


Protein-protein Interactions for TIAM1
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in TIAM1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members PDZ IPR001478 0.15
Category members PH_domain IPR001849 0.14
Category members DH-domain IPR000219 0.05
Category members Raf-like_ras-bd IPR003116 0


Protein complexes (CORUM database) featuring TIAM1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5190 TIAM1-EFNB1-EPHA2 complex Database 0
Category members Corum 5409 TIAM1-GRIN1 complex Database 0


Categories featuring TIAM1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_292 PID_ECADHERIN_NASCENT_AJ_PATHWAY 0 2.74
Category members Pathway Pathway_221 REACTOME_SIGNALLING_BY_NGF 0 2.14
Category members GO Category GO:0005911 cell-cell junction Database 1.4
Category members Pathway Pathway_243 REACTOME_GPCR_DOWNSTREAM_SIGNALING 0 1.27
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_237 PID_LYSOPHOSPHOLIPID_PATHWAY 0 1.09
Category members Pathway Pathway_256 REACTOME_SIGNALING_BY_GPCR 0 0.83
Category members Pathway Pathway_568 PID_CDC42_PATHWAY 0 0.68
Category members GO Category GO:0048011 neurotrophin TRK receptor signaling pathway Database 0.63
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0046875 ephrin receptor binding Database 0.3
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members Pathway Pathway_739 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING 0 0.23
Category members Pathway Pathway_779 REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE 0 0.2
Category members Pathway Pathway_294 PID_AJDISS_2PATHWAY 0 0.18
Category members GO Category GO:0035023 regulation of Rho protein signal transduction Database 0.17
Category members Pathway Pathway_1140 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK 0 0.1
Category members GO Category GO:0031234 extrinsic to cytoplasmic side of plasma membrane Database 0.1
Category members Pathway Pathway_580 KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 0 0.08
Category members Pathway Pathway_296 PID_ARF6_DOWNSTREAM_PATHWAY 0 0.08
Category members GO Category GO:0005089 Rho guanyl-nucleotide exchange factor activity Database 0.08
Category members Pathway Pathway_511 PID_EPHA2_FWD_PATHWAY 0 0.05
Category members Pathway Pathway_644 PID_TRKR_PATHWAY 0 0.04
Category members Pathway Pathway_1157 PID_RAC1_REG_PATHWAY 0 0
Category members Pathway Pathway_252 KEGG_CHEMOKINE_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_519 REACTOME_SIGNALING_BY_RHO_GTPASES 0 0
Category members Pathway Pathway_547 PID_EPHRINB_REV_PATHWAY 0 0
Category members Pathway Pathway_623 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS 0 0
Category members GO Category GO:0005057 receptor signaling protein activity Database 0
Category members GO Category GO:0005085 guanyl-nucleotide exchange factor activity Database 0
Category members GO Category GO:0005543 phospholipid binding Database 0
Category members GO Category GO:0007160 cell-matrix adhesion Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0016477 cell migration Database 0
Category members GO Category GO:0016601 Rac protein signal transduction Database 0
Category members GO Category GO:0030676 Rac guanyl-nucleotide exchange factor activity Database 0
Category members GO Category GO:0044291 cell-cell contact zone Database 0
Category members GO Category GO:0048013 ephrin receptor signaling pathway Database 0
Category members GO Category GO:0050772 positive regulation of axonogenesis Database 0


.

© Copyright Svejstrup Laboratory 2015