RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
DNM1	1	-0.280	0.150		1.049	-1.435	1.593	1.013
CCND1	1	-1.820	3.470
PLCG1	1	-0.170	0.000
MCF2L	1	2.560	-1.220
KRAS	1	-0.510	0.620				1.031	0.887
KRAS	1	-0.510	0.620				0.246	-0.346
DYNLT1	1	-1.630	2.830
MAP2K1	1	-1.590	2.780
RHOG	1	0.080	-0.800	1.988			-0.433	-0.542
NRAS	1	1.810	-0.720				0.246	-0.346
NEDD4L	0	-0.050	-0.110
RHOA	0	-0.510	1.370	-0.485			0.532	0.279
PRKCZ	0	-0.290	0.310
CDC42	0	-0.170	0.490	-0.597			-1.527	-1.013
CDC42	0	1.240	-0.940	-0.597			-1.527	-1.013
ABL1	0	0.670	-0.070
CRKL	0	0.290	-0.620
MAPK3	0
DNAJA3	0	-0.010	-0.240	0.786	0.226	-0.161	-0.800	-0.347
EHD4	0			0.691			-0.976	-0.173
RAPGEF1	0	1.620	-0.780
GAB1	0	1.950	-1.110
SOS1	0	0.500	-0.620	-0.570
PIK3CA	0
GIPC1	0	0.050	-0.100
RAP1B	0	-0.520	0.540	-0.200			0.374	0.556
ARHGAP32	0	0.480	-0.120
RAC1	0	-0.580	1.580	0.486			-0.364	-0.568
PIK3R1	0	1.910	-1.220				-0.441	0.147
TIAM1	0	-0.620	0.220
FAIM	0	-0.410	0.770	-1.123
SQSTM1	0	-0.860	1.770	-2.165			-2.063	-1.741
SQSTM1	0	-0.440	0.530	-2.165			-2.063	-1.741
PRKCI	0	0.730	-0.460	1.483			0.192	0.350
CRK	0	-0.790	0.230
STAT3	0	0.200	-1.270					0.334
HRAS	0	1.470	-0.520
GRB2	0	-0.240	0.300		-1.021	0.057	0.906
SH2B1	0	0.970	0.010
PTPN11	0	-0.210	-0.400	0.644			1.053	0.451

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
ABL1	Phosphorylation	S1083	-1.131	-0.857	_GQGESDPLDHEPAVS(ph)PLLPR_
ABL1	Phosphorylation	S1134		0.293	_SSS(ph)FREMDGQPER_
ABL1	Phosphorylation	S1232	0.821	0.183	_SCS(ph)ASCVPHGAK_
ARHGAP32	Phosphorylation	S703		0.067	_S(ph)AKSEESLTSLHAVDGDSK_
ARHGAP32	Phosphorylation	S706	0.359	0.358	_SAKS(ph)EESLTSLHAVDGDSK_
ARHGAP32	Phosphorylation	S871	0.466	0.562	_LSPFFTLDLS(ph)PTEDK_
CCND1	Ubiquitylation	K33		-0.490	_AMLK(gl)AEETCAPSVSYFK_
CCND1	Ubiquitylation	K46	-1.016	-0.036	_AEETCAPSVSYFK(gl)CVQK_
CCND1	Ubiquitylation	K95	-0.733	-0.137	_FLSLEPVK(gl)K_
CCND1	Ubiquitylation	K96	-0.846	-0.155	_FLSLEPVKK(gl)_
CCND1	Ubiquitylation	K238		0.245	_VIK(gl)CDPDCLR_
CDC42	Ubiquitylation	K173	-1.839		_DDPSTIEK(gl)LAK_
CDC42	Ubiquitylation	K178	-0.801	-0.716	_NK(gl)QKPITPETAEK_
CDC42	Ubiquitylation	K180	-1.806		_QK(gl)PITPETAEK(gl)LAR_
CDC42	Ubiquitylation	K189	-1.082		_QKPITPETAEK(gl)LAR_
CDC42	Ubiquitylation	K198	0.550	1.159	_AVK(gl)YVECSALTQK_
CDC42	Ubiquitylation	K208	-0.937	0.038	_YVECSALTQK(gl)GLK_
CDC42	Ubiquitylation	K228	-2.488		_NVFDEAILAALEPPEPK(gl)K_
CDC42	Ubiquitylation	K229	-1.254		_NVFDEAILAALEPPEPKK(gl)_
CRK	Phosphorylation	S40	0.533	0.363	_DS(ph)STSPGDYVLSVSENSR_
CRK	Phosphorylation	S41	1.065	0.801	_DSS(ph)TSPGDYVLSVSENSR_
CRKL	Phosphorylation	S41		0.868	_DS(ph)STCPGDYVLSVSENSR_
CRKL	Phosphorylation	S107	-0.818	-1.177	_YPS(ph)PPMGSVSAPNLPTAEDNLEYVR_
DNM1	Ubiquitylation	K393	0.542		_EISYAIK(gl)NIHGVR_
DNM1	Phosphorylation	S764	-2.106	-1.205	_EALNIIGDISTSTVSTPVPPPVDDTWLQSASSHS(ph)PTPQR_
DYNLT1	Phosphorylation	Y4	0.117		_M(ox)EDY(ph)QAAEETAFVVDEVSNIVK_
EHD4	Ubiquitylation	K165	0.180	-0.366	_SISVIDSPGILSGEK(gl)QR_
EHD4	Ubiquitylation	K291		-1.021	_DIQSLPQK(gl)AAVR_
FAIM	Ubiquitylation	K62	0.012		_ETFYVGAAKTK(gl)_
GAB1	Phosphorylation	S266	0.756	0.551	_SYS(ph)HDVLPK_
GAB1	Phosphorylation	S367	0.230	0.176	_TAS(ph)DTDSSYCIPTAGMS(ph)PSR_
GAB1	Phosphorylation	T369		-0.352	_TASDT(ph)DSSYCIPTAGMS(ph)PSR_
GAB1	Phosphorylation	S381	-0.481	0.139	_TASDTDSSYCIPTAGM(ox)S(ph)PSR_
GAB1	Phosphorylation	S401	0.266	0.788	_DAS(ph)SQDCYDIPR_
GAB1	Phosphorylation	S402	0.328	0.633	_DASS(ph)QDCYDIPR_
GAB1	Phosphorylation	S419		0.540	_SSS(ph)LEGFHNHFK_
GIPC1	Ubiquitylation	K80	0.463		_IEGFTNVK(gl)ELYGK_
GIPC1	Ubiquitylation	K199	-0.691	-0.589	_LLK(gl)ELPR_
GIPC1	Ubiquitylation	K210		-0.064	_TFTLK(gl)LTEPR_
GRB2	Ubiquitylation	K10	0.146		_YDFK(gl)ATADDELSFK_
GRB2	Ubiquitylation	K20	-0.078		_ATADDELSFK(gl)R_
GRB2	Ubiquitylation	K69	-0.362	0.641	_AK(gl)AEEMLSK_
GRB2	Ubiquitylation	K76	0.754		_AEEMLSK(gl)QR_
GRB2	Ubiquitylation	K109	0.381	-0.002	_FGNDVQHFK(gl)VLR_
HRAS	Ubiquitylation	K170	-1.005		_K(gl)LNPPDESGPGCMSCK_
KRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
KRAS	Ubiquitylation	K235	0.591	0.087	_TVDTK(gl)QAQDLAR_
KRAS	Ubiquitylation	K254	-0.450	-0.156	_SYGIPFIETSAK(gl)TR_
MAP2K1	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K1	Phosphorylation	S385		0.066	_RSDAEEVDFAGWLCSTIGLNQPS(ph)TPTHAAGV_
MAP2K1	Phosphorylation	T386		0.377	_RSDAEEVDFAGWLCSTIGLNQPST(ph)PTHAAGV_
MAPK3	Phosphorylation	Y204	-0.807	-2.487	_IADPEHDHTGFLTEY(ph)VATR_
MAPK3	Ubiquitylation	K289		-0.608	_NYLQSLPSKTK(gl)_
MCF2L	Phosphorylation	S90	-0.968	-0.792	_ALEQSQS(ph)LPLPAPT(ph)STSPSR_
MCF2L	Phosphorylation	S100	-0.927	-0.748	_ALEQSQSLPLPAPTSTS(ph)PSR_
NEDD4L	Ubiquitylation	K149	-0.001	0.036	_LK(gl)MAYMPK_
NEDD4L	Phosphorylation	T302	0.166	0.120	_T(ph)SPQELSEELSR_
NEDD4L	Phosphorylation	S303	0.166	0.120	_T(ph)SPQELSEELSR_
NEDD4L	Phosphorylation	S448	0.067	-0.137	_SLS(ph)SPTVTLSAPLEGAK_
NEDD4L	Phosphorylation	S449	-0.460	-0.435	_SLSS(ph)PTVTLSAPLEGAK_
NEDD4L	Ubiquitylation	K462	-0.635	-0.011	_SLSSPTVTLSAPLEGAK(gl)DSPVRR_
NEDD4L	Ubiquitylation	K471	-0.787		_AVK(gl)DTLSNPQSPQPSPYNSPKPQHK_
NEDD4L	Ubiquitylation	K531		0.704	_LK(gl)FPVHMR_
NEDD4L	Ubiquitylation	K539	-1.106	-1.175	_SK(gl)TSLNPNDLGPLPPGWEER_
NEDD4L	Ubiquitylation	K639	0.649	0.864	_IMSVK(gl)RPDVLK_
NRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
PIK3CA	Ubiquitylation	K864	0.390	0.588	_NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA	Ubiquitylation	K868	0.204	0.651	_NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA	Ubiquitylation	K974	-0.273		_GAQECTK(gl)TREFER_
PLCG1	Ubiquitylation	K300		8.031	_DLK(gl)NMLSQVNYR_
PLCG1	Ubiquitylation	K348		-0.219	_SLMYSAQK(gl)TMDLPFLEASTLR_
PLCG1	Ubiquitylation	K552		-0.355	_NMAQYFK(gl)K_
PLCG1	Ubiquitylation	K553		-0.355	_NMAQYFK(gl)K_
PLCG1	Ubiquitylation	K1063	0.864	0.355	_LTEGK(gl)IMER_
PLCG1	Phosphorylation	S1370	0.475	0.515	_AREGS(ph)FESR_
PRKCI	Ubiquitylation	K244	0.289		_ESGK(gl)ASSSLGLQDFDLLR_
PRKCI	Ubiquitylation	K488	-0.090	0.847	_SLSVK(gl)AASVLK_
PRKCZ	Phosphorylation	T560	-0.884	-1.578	_KQALPPFQPQITDDYGLDNFDTQFTSEPVQLT(ph)PDDEDAIKR_
PTPN11	Ubiquitylation	K124	0.562		_EAEK(gl)LLTEK_
RAC1	Ubiquitylation	K115	-1.745	-0.215	_AK(gl)WYPEVR_
RAC1	Ubiquitylation	K142	0.492		_LDLRDDK(gl)DTIEK_
RAC1	Ubiquitylation	K152	0.099	-0.292	_K(gl)LTPITYPQGLAMAK_
RAC1	Ubiquitylation	K166	-0.981	-0.655	_LTPITYPQGLAMAK(gl)EIGAVK_
RAC1	Ubiquitylation	K172	1.026	0.412	_EIGAVK(gl)YLECSALTQR_
RAC1	Ubiquitylation	K185	-0.113	0.578	_GLK(gl)TVFDEAIR_
RAC1	Ubiquitylation	K202	-1.379	-1.447	_AVLCPPPVK(gl)KR_
RAC1	Ubiquitylation	K203	-1.708	-1.447	_AVLCPPPVKK(gl)_
RAP1B	Ubiquitylation	K174	0.197		_KTPVPGK(gl)AR_
RAPGEF1	Phosphorylation	S377		0.629	_LSKS(ph)DEQLSSLDR_
RHOA	Ubiquitylation	K6	0.708		_K(gl)KLVIVGDGACGK_
RHOA	Ubiquitylation	K7	0.708		_K(gl)KLVIVGDGACGK_
RHOA	Ubiquitylation	K118	-0.408		_HFCPNVPIILVGNK(gl)K_
RHOA	Ubiquitylation	K119	-0.408		_HFCPNVPIILVGNK(gl)K_
RHOA	Ubiquitylation	K135	-0.528	-0.796	_MK(gl)QEPVKPEEGRDMANR_
RHOA	Ubiquitylation	K162	0.345	0.453	_IGAFGYMECSAK(gl)TK_
RHOG	Ubiquitylation	K183	-0.963		_AVLNPTPIK(gl)R_
SH2B1	Phosphorylation	S96	0.112	-0.143	_ASGSLSPPILAPLS(ph)PGAEISPHDLSLESCR_
SH2B1	Phosphorylation	S125	0.018	0.257	_S(ph)SEDLAGPLPSSVSSSSTTSSKPK_
SH2B1	Phosphorylation	S126	0.018	0.257	_S(ph)SEDLAGPLPSSVSSSSTTSSKPK_
SOS1	Phosphorylation	S1082	0.278		_IPESETESTASAPNS(ph)PR_
SOS1	Phosphorylation	S1166	0.097	-0.094	_RPESAPAES(ph)SPSK_
SQSTM1	Ubiquitylation	K13	0.150	0.302	_AYLLGK(gl)EDAAR_
SQSTM1	Phosphorylation	S28		-0.721	_RFSFCCS(ph)PEPEAEAEAAAGPGPCER_
SQSTM1	Ubiquitylation	K141	-0.915		_YK(gl)CSVCPDYDLCSVCEGK_
SQSTM1	Ubiquitylation	K157	-0.852	-0.677	_CSVCPDYDLCSVCEGK(gl)GLHR_
SQSTM1	Phosphorylation	T269	-0.681	-0.421	_LT(ph)PVS(ph)PESSSTEEK_
SQSTM1	Phosphorylation	S272	0.171	0.044	_LTPVS(ph)PESSSTEEK_
SQSTM1	Phosphorylation	S332		-0.007	_IALESEGRPEEQMESDNCS(ph)GGDDDWTHLSSK_
SQSTM1	Ubiquitylation	K420	-1.122	-0.061	_LLQTK(gl)NYDIGAALDTIQYSK_
SQSTM1	Ubiquitylation	K435	-1.352	-0.780	_NYDIGAALDTIQYSK(gl)HPPPL_
STAT3	Ubiquitylation	K177	0.957		_VVENLQDDFDFNYK(gl)TLK_
STAT3	Ubiquitylation	K180	1.179		_TLK(gl)SQGDMQDLNGNNQSVTR_
STAT3	Ubiquitylation	K244	0.262		_TLTDEELADWK(gl)R_
STAT3	Phosphorylation	T714		-0.338	_FICVT(ph)PTTCSNTIDLPMS(ph)PR_
STAT3	Phosphorylation	S727	-0.079	0.156	_FICVTPTTCSNTIDLPMS(ph)PR_
TIAM1	Phosphorylation	S231	0.453	0.331	_ANS(ph)LGDLYAQK_
TIAM1	Phosphorylation	T1405	0.267		_T(ph)ESLPSSQQYVPFGGK_
TIAM1	Phosphorylation	S1407	-0.862	-0.252	_TES(ph)LPSSQQYVPFGGK_