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Query: DNM1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DNM1 1 -0.399 -0.280 0.150 1.049 -1.435 1.593 1.013

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DNM1 Phosphorylation S764 -2.106 -1.205 _EALNIIGDISTSTVSTPVPPPVDDTWLQSASSHS(ph)PTPQR_
DNM1 Ubiquitylation K393 0.542 _EISYAIK(gl)NIHGVR_

Background Information for DNM1:


Pubmed-DNM1 »
Uniprot-DNM1 »
Biogrid-DNM1 »
ProteomicsDB-DNM1 »

Tumorportal-DNM1 »
COSMIC-DNM1 »
GenomeRNAi-DNM1 »
Genecards-DNM1


Protein-protein Interactions for DNM1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C14orf104 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDKAL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DGUOK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DNM3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GRB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HAX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUFIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCN2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC39A9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNX9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TBC1D15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM9B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZBBX Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DNM1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Dynamin_GTPase IPR001401 0.36
Category members Dynamin_central IPR000375 0.33
Category members GED IPR003130 0.33
Category members PH_domain IPR001849 0.14
Category members Dynamin_SF IPR022812 0.11


Protein complexes (CORUM database) featuring DNM1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2300 Profilin 2 complex Database 0


Categories featuring DNM1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0043234 protein complex Database 2.73
Category members Pathway Pathway_259 REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE 0 2.34
Category members Pathway Pathway_221 REACTOME_SIGNALLING_BY_NGF 0 2.14
Category members GO Category GO:0008022 protein C-terminus binding Database 1.43
Category members Pathway Pathway_645 PID_CXCR4_PATHWAY 0 1.42
Category members Pathway Pathway_1075 REACTOME_L1CAM_INTERACTIONS 0 1.32
Category members Pathway Pathway_666 KEGG_ENDOCYTOSIS 0 1.25
Category members GO Category GO:0005874 microtubule Database 1.21
Category members Pathway Pathway_474 REACTOME_MEMBRANE_TRAFFICKING 0 1.14
Category members Pathway Pathway_673 REACTOME_AXON_GUIDANCE 0 1.06
Category members Pathway Pathway_662 PID_IL8_CXCR2_PATHWAY 0 0.62
Category members Pathway Pathway_1265 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION 0 0.6
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members GO Category GO:0006897 endocytosis Database 0.31
Category members Pathway Pathway_460 REACTOME_INNATE_IMMUNE_SYSTEM 0 0.29
Category members Pathway Pathway_849 PID_NOTCH_PATHWAY 0 0.29
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members Pathway Pathway_428 PID_THROMBIN_PAR1_PATHWAY 0 0.18
Category members Pathway Pathway_527 REACTOME_TOLL_RECEPTOR_CASCADES 0 0.17
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members Pathway Pathway_629 PID_EPHB_FWD_PATHWAY 0 0.14
Category members GO Category GO:0007032 endosome organization Database 0.11
Category members Pathway Pathway_499 KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS 0 0.1
Category members Pathway Pathway_297 BIOCARTA_NDKDYNAMIN_PATHWAY 0 0.08
Category members Pathway Pathway_1268 REACTOME_GAP_JUNCTION_DEGRADATION 0 0.08
Category members Pathway Pathway_1136 REACTOME_RECYCLING_PATHWAY_OF_L1 0 0.04
Category members Pathway Pathway_644 PID_TRKR_PATHWAY 0 0.04
Category members GO Category GO:0031623 receptor internalization Database 0.02
Category members Pathway Pathway_663 PID_IL8_CXCR1_PATHWAY 0 0.01
Category members Pathway Pathway_1180 BIOCARTA_GABA_PATHWAY 0 0.01
Category members Pathway Pathway_1146 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING 0 0
Category members Pathway Pathway_1267 REACTOME_GAP_JUNCTION_TRAFFICKING 0 0
Category members Pathway Pathway_217 BIOCARTA_BARRESTIN_PATHWAY 0 0
Category members Pathway Pathway_231 BIOCARTA_BARRESTIN_SRC_PATHWAY 0 0
Category members Pathway Pathway_264 BIOCARTA_BARR_MAPK_PATHWAY 0 0
Category members Pathway Pathway_430 PID_TXA2PATHWAY 0 0
Category members Pathway Pathway_538 PID_ERBB1_INTERNALIZATION_PATHWAY 0 0
Category members Pathway Pathway_547 PID_EPHRINB_REV_PATHWAY 0 0
Category members Pathway Pathway_655 PID_CXCR3_PATHWAY 0 0
Category members Disease phenotype Epileptic_encephalopathy Epileptic encephalopathy Database 0
Category members GO Category GO:0006898 receptor-mediated endocytosis Database 0
Category members GO Category GO:0030117 membrane coat Database 0


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