RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
PIK3R2	1	2.740	-1.180				0.269	0.348
DNM1	1	-0.280	0.150		1.049	-1.435	1.593	1.013
STAMBP	1	-1.500	2.650
RAF1	1	2.020	-1.230
KRAS	1	-0.510	0.620				1.031	0.887
KRAS	1	-0.510	0.620				0.246	-0.346
NRAS	1	1.810	-0.720				0.246	-0.346
PIK3CB	0	-1.390	2.350
PIK3CB	0	-0.710	1.450
EPN1	0	0.000	-0.210	0.286			0.676	0.159
CDC42	0	-0.170	0.490	-0.597			-1.527	-1.013
CDC42	0	1.240	-0.940	-0.597			-1.527	-1.013
TSG101	0	0.060	-0.480
EPS15	0	0.580	-0.640
EPS15	0	0.580	-0.640
ARHGEF7	0	-0.410	-0.070
SH3GL2	0	0.310	-0.450
UBE2D3	0	-1.120	1.910		-0.582	-0.725	-0.315
SOS1	0	0.500	-0.620	-0.570
PIK3R3	0	-0.140	-0.480
PIK3R3	0	-0.140	-0.480				-0.441	0.147
PIK3CA	0
UBE2D2	0	-0.010	1.100		-0.582	-0.725	-0.315
UBE2D2	0	-0.010	1.100
USP8	0	0.830	-0.320
RAB5A	0	-0.440	0.910				0.089	-0.362
RAB5A	0	0.080	0.240				0.089	-0.362
LRIG1	0	-1.220	1.350
PIK3R1	0	1.910	-1.220				-0.441	0.147
EGFR	0	-0.580	0.520				0.513	0.090
SH3KBP1	0	-0.400	-0.020	-0.522
SYNJ1	0	0.310	-0.210
ZFYVE28	0
HRAS	0	1.470	-0.520
GRB2	0	-0.240	0.300		-1.021	0.057	0.906
HGS	0	0.020	0.300	-0.211			0.737	0.264
SRC	0	0.050	0.470	-0.031
ITSN1	0	-0.670	0.610
ITSN1	0	-0.670	0.610				0.287	0.672

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
ARHGEF7	Phosphorylation	S50	1.374	1.424	_IKS(ph)FDSLGSQSLHTR_
ARHGEF7	Phosphorylation	S154	-0.198	0.140	_SGTLKS(ph)PPK_
ARHGEF7	Phosphorylation	S415	0.662	0.947	_M(ox)S(ph)GFIYQGK_
ARHGEF7	Phosphorylation	S600		0.797	_S(ph)TAALEEDAQILK_
ARHGEF7	Phosphorylation	T601		0.797	_S(ph)TAALEEDAQILK_
ARHGEF7	Phosphorylation	S635	0.061	-0.203	_KES(ph)APQVLLPEEEKIIVEETK_
CDC42	Ubiquitylation	K173	-1.839		_DDPSTIEK(gl)LAK_
CDC42	Ubiquitylation	K178	-0.801	-0.716	_NK(gl)QKPITPETAEK_
CDC42	Ubiquitylation	K180	-1.806		_QK(gl)PITPETAEK(gl)LAR_
CDC42	Ubiquitylation	K189	-1.082		_QKPITPETAEK(gl)LAR_
CDC42	Ubiquitylation	K198	0.550	1.159	_AVK(gl)YVECSALTQK_
CDC42	Ubiquitylation	K208	-0.937	0.038	_YVECSALTQK(gl)GLK_
CDC42	Ubiquitylation	K228	-2.488		_NVFDEAILAALEPPEPK(gl)K_
CDC42	Ubiquitylation	K229	-1.254		_NVFDEAILAALEPPEPKK(gl)_
DNM1	Ubiquitylation	K393	0.542		_EISYAIK(gl)NIHGVR_
DNM1	Phosphorylation	S764	-2.106	-1.205	_EALNIIGDISTSTVSTPVPPPVDDTWLQSASSHS(ph)PTPQR_
EGFR	Phosphorylation	T693	0.486	-0.139	_ELVEPLT(ph)PSGEAPNQALLR_
EGFR	Phosphorylation	S991		-0.041	_MHLPS(ph)PTDSNFYR_
EPN1	Ubiquitylation	K97	-0.214	0.731	_VSQQCK(gl)ENMYAVQTLK_
EPN1	Ubiquitylation	K107	-0.288	1.227	_ENMYAVQTLK(gl)DFQYVDR_
EPN1	Ubiquitylation	K117	0.237		_DFQYVDRDGK(gl)DQGVNVR_
EPN1	Ubiquitylation	K128	0.126		_AK(gl)QLVALLRDEDR_
EPN1	Phosphorylation	S417	0.164		_TALPTS(ph)GSSAGELELLAGEVPAR_
EPN1	Phosphorylation	S420	-0.776	-0.436	_TALPTSGSS(ph)AGELELLAGEVPAR_
EPN1	Phosphorylation	S435	0.801	0.890	_S(ph)PGAFDMSGVR_
EPN1	Phosphorylation	T470	-1.386	-1.782	_T(ph)PESFLGPNAALVDLDSLVSRPGPTPPGAK_
EPN1	Phosphorylation	S473	-0.700	-0.430	_KTPES(ph)FLGPNAALVDLDSLVSR_
EPS15	Phosphorylation	S108	-1.380	-0.251	_FHDTSS(ph)PLLISGTSAAELPWAVKPEDK_
EPS15	Phosphorylation	S324	1.499	1.080	_NIIGSS(ph)PVADFSAIK_
EPS15	Phosphorylation	S428	-0.224	-0.557	_S(ph)SPELLPSGVTDENEVTTAVTEK_
EPS15	Phosphorylation	S429	-0.224	-0.308	_S(ph)SPELLPSGVTDENEVTTAVTEK_
EPS15	Ubiquitylation	K620	0.143	0.541	_SATSSSVSNVVITK(gl)NVFEETSVK_
EPS15	Ubiquitylation	K654	-2.207	-1.253	_IGTPTRPCPLPPGK(gl)R_
EPS15	Phosphorylation	S662	1.046	0.458	_SINKLDS(ph)PDPFK_
EPS15	Phosphorylation	S814	-0.764	-0.870	_LNDPFQPFPGNDS(ph)PKEKDPEIFCDPFTSATTTTNK_
GRB2	Ubiquitylation	K10	0.146		_YDFK(gl)ATADDELSFK_
GRB2	Ubiquitylation	K20	-0.078		_ATADDELSFK(gl)R_
GRB2	Ubiquitylation	K69	-0.362	0.641	_AK(gl)AEEMLSK_
GRB2	Ubiquitylation	K76	0.754		_AEEMLSK(gl)QR_
GRB2	Ubiquitylation	K109	0.381	-0.002	_FGNDVQHFK(gl)VLR_
HGS	Ubiquitylation	K126	0.088	0.464	_YK(gl)VVQDTYQIMK_
HGS	Ubiquitylation	K192	0.015	0.751	_ACGQIFCGK(gl)CSSK_
HGS	Ubiquitylation	K202	-0.163	0.558	_YSTIPK(gl)FGIEK_
HGS	Ubiquitylation	K207	-0.193	0.798	_FGIEK(gl)EVR_
HGS	Ubiquitylation	K283	-0.826	-0.270	_QK(gl)STYTSYPK_
HGS	Ubiquitylation	K337	0.097		_NYWEK(gl)KQEEAR_
HGS	Ubiquitylation	K473	-0.154		_LYYEGLQDK(gl)LAQIR_
HGS	Ubiquitylation	K513	-0.289		_QIQLAQK(gl)LEIMR_
HGS	Ubiquitylation	K520	0.211	1.230	_QK(gl)KQEYLEVQR_
HGS	Ubiquitylation	K521	-1.344	1.230	_K(gl)QEYLEVQR_
HGS	Ubiquitylation	K551	-0.260	0.554	_LEQQK(gl)QTVQM(ox)R_
HRAS	Ubiquitylation	K170	-1.005		_K(gl)LNPPDESGPGCMSCK_
ITSN1	Phosphorylation	S203	-0.497	-0.811	_AQS(ph)FDVASVPPVAEWAVPQSSR_
ITSN1	Phosphorylation	S313	0.882	0.188	_S(ph)GSGISVISSTSVDQR_
ITSN1	Phosphorylation	S315	0.675	0.750	_SGS(ph)GISVISSTSVDQR_
ITSN1	Ubiquitylation	K569		0.570	_DSLVTLK(gl)R_
ITSN1	Ubiquitylation	K583		0.151	_NMQFSNTPDSGVSLLHK(gl)K_
ITSN1	Ubiquitylation	K584		-0.412	_NMQFSNTPDSGVSLLHKK(gl)_
ITSN1	Ubiquitylation	K596	1.277		_LK(gl)EQLDALEK_
ITSN1	Phosphorylation	S889	-0.357	-0.319	_TVSPGSVS(ph)PIHGQGQVVENLK_
ITSN1	Phosphorylation	S904	-0.681	-0.729	_SAFTPATATGSSPS(ph)PVLGQGEK_
ITSN1	Phosphorylation	S978	1.075	0.684	_STS(ph)MDSGSSESPASLK_
KRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
KRAS	Ubiquitylation	K235	0.591	0.087	_TVDTK(gl)QAQDLAR_
KRAS	Ubiquitylation	K254	-0.450	-0.156	_SYGIPFIETSAK(gl)TR_
LRIG1	Phosphorylation	S1069	-0.682		_ACDAS(ph)PESTPLTGQLPGK_
NRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
PIK3CA	Ubiquitylation	K864	0.390	0.588	_NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA	Ubiquitylation	K868	0.204	0.651	_NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA	Ubiquitylation	K974	-0.273		_GAQECTK(gl)TREFER_
PIK3CB	Ubiquitylation	K1044		0.990	_SEEEALKQFKQK(gl)_
PIK3R2	Phosphorylation	S262		-2.237	_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2	Phosphorylation	S263		-2.237	_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2	Ubiquitylation	K500	-0.189		_IFEEQGQTQEK(gl)CSK_
PIK3R2	Ubiquitylation	K541	-0.609		_TK(gl)LEQQLR_
PIK3R2	Ubiquitylation	K564	-0.431	-1.022	_MNSLK(gl)PDLMQLR_
PIK3R3	Ubiquitylation	K226		-0.376	_YQQDQLVKEDNIDAVGKK(gl)_
PIK3R3	Ubiquitylation	K320		0.385	_LGEIHDSK(gl)MR_
RAF1	Phosphorylation	S29	0.028	-0.571	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	T31	0.028	-0.669	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	S244		0.053	_YSTPHAFTFNTSS(ph)PSSEGSLSQR_
RAF1	Phosphorylation	S259	-0.069	0.054	_STS(ph)TPNVHM(ox)VSTTLPVDSR_
RAF1	Phosphorylation	S301		-0.651	_SHSESASPSALSSSPNNLS(ph)PTGWSQPK_
RAF1	Phosphorylation	T303		-0.664	_SHSESASPSALSSSPNNLSPT(ph)GWSQPK_
RAF1	Phosphorylation	S497		-0.449	_SRWS(ph)GSQQVEQPTGSVLWMAPEVIR_
RAF1	Phosphorylation	S621	0.212	0.271	_SAS(ph)EPSLHR_
RAF1	Phosphorylation	S642	-0.197	0.463	_AAHTEDINACTLTTS(ph)PR_
SH3GL2	Ubiquitylation	K7		-0.268	_(ac)SVAGLK(gl)K_
SH3GL2	Ubiquitylation	K8	-0.654		_(ac)SVAGLKK(gl)_
SH3GL2	Ubiquitylation	K177	-0.477	0.450	_QGK(gl)IPDEELR_
SH3KBP1	Phosphorylation	S230	0.300	0.186	_S(ph)IEVENDFLPVEK_
SOS1	Phosphorylation	S1082	0.278		_IPESETESTASAPNS(ph)PR_
SOS1	Phosphorylation	S1166	0.097	-0.094	_RPESAPAES(ph)SPSK_
SRC	Phosphorylation	S17	-0.604	-0.689	_S(ph)LEPAENVHGAGGGAFPASQTPSKPASADGHR_
SRC	Phosphorylation	S75	0.060	0.331	_LFGGFNSSDTVTS(ph)PQR_
STAMBP	Ubiquitylation	K96	-0.832		_LK(gl)EIAFPK_
STAMBP	Ubiquitylation	K107	0.530	-0.048	_AEELK(gl)AELLK_
STAMBP	Ubiquitylation	K144	-0.041		_NMAIQQELEK(gl)EK_
STAMBP	Ubiquitylation	K146	-0.693		_NMAIQQELEKEK(gl)QR_
STAMBP	Ubiquitylation	K180		0.159	_LK(gl)IVQEFGK_
SYNJ1	Phosphorylation	T1220	-0.313	-0.087	_ASAGRLT(ph)PESQSK_
SYNJ1	Phosphorylation	S1391	-1.402	-0.873	_S(ph)SPNPFITGLTR_
SYNJ1	Phosphorylation	S1392	-0.543	-0.378	_SS(ph)PNPFITGLTR_
SYNJ1	Phosphorylation	S1565	0.717	0.918	_AS(ph)PTLDFTER_
TSG101	Ubiquitylation	K237	-1.467	0.252	_ASLISAVSDK(gl)LR_
TSG101	Ubiquitylation	K257	0.192	0.329	_AQAELNALK(gl)R_
UBE2D2	Ubiquitylation	K8	0.326		_INK(gl)ELSDLAR_
UBE2D2	Ubiquitylation	K8	0.526		_IHK(gl)ELNDLAR_
UBE2D2	Ubiquitylation	K101	-0.229		_SQWSPALTISK(gl)_
UBE2D2	Ubiquitylation	K128	0.754		_IYK(gl)TDRDK(gl)YNR_
UBE2D2	Ubiquitylation	K128	0.918		_IYK(gl)TDREK_
UBE2D2	Ubiquitylation	K133	0.005		_IYK(gl)TDRDK(gl)YNR_
UBE2D2	Ubiquitylation	K144	0.212	0.074	_EWTQK(gl)YAM_
UBE2D3	Ubiquitylation	K8	0.326		_INK(gl)ELSDLAR_
UBE2D3	Ubiquitylation	K101	-0.229		_SQWSPALTISK(gl)_
UBE2D3	Ubiquitylation	K128	0.754		_IYK(gl)TDRDK(gl)YNR_
UBE2D3	Ubiquitylation	K133	0.005		_IYK(gl)TDRDK(gl)YNR_
UBE2D3	Ubiquitylation	K144	0.212	0.074	_EWTQK(gl)YAM_
USP8	Phosphorylation	S392	-0.015	0.284	_SDVS(ph)PIIQPVPSIK_
USP8	Phosphorylation	T577	-0.048	0.069	_RCPT(ph)PEIQKK_
USP8	Phosphorylation	S716	0.750	0.023	_S(ph)YSSPDITQAIQEEEKR_
USP8	Phosphorylation	S718	0.338	0.273	_SYS(ph)SPDITQAIQEEEKR_
ZFYVE28	Ubiquitylation	K87	-0.163	-0.341	_DFCVK(gl)FPEEIR_