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Query: SYNJ1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SYNJ1 0 1.635 0.310 -0.210

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SYNJ1 Phosphorylation S1565 0.717 0.918 _AS(ph)PTLDFTER_
SYNJ1 Phosphorylation T1220 -0.313 -0.087 _ASAGRLT(ph)PESQSK_
SYNJ1 Phosphorylation S1392 -0.543 -0.378 _SS(ph)PNPFITGLTR_
SYNJ1 Phosphorylation S1391 -1.402 -0.873 _S(ph)SPNPFITGLTR_

Background Information for SYNJ1:


Pubmed-SYNJ1 »
Uniprot-SYNJ1 »
Biogrid-SYNJ1 »
ProteomicsDB-SYNJ1 »

Tumorportal-SYNJ1 »
COSMIC-SYNJ1 »
GenomeRNAi-SYNJ1 »
Genecards-SYNJ1


Protein-protein Interactions for SYNJ1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GTSE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ALKBH2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AP2M1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GRB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNX9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SYNJ1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members Syja_N IPR002013 0.18
Category members IPPc IPR000300 0.1
Category members Endo/exonuclease/phosphatase IPR005135 0
Category members DUF1866 IPR015047 0


Protein complexes (CORUM database) featuring SYNJ1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SYNJ1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0046855 inositol phosphate dephosphorylation Database 0.58
Category members GO Category GO:0046856 phosphatidylinositol dephosphorylation Database 0.35
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0042578 phosphoric ester hydrolase activity Database 0.31
Category members Pathway Pathway_106 KEGG_INOSITOL_PHOSPHATE_METABOLISM 0 0.28
Category members GO Category GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity Database 0.23
Category members Pathway Pathway_629 PID_EPHB_FWD_PATHWAY 0 0.14
Category members Pathway Pathway_297 BIOCARTA_NDKDYNAMIN_PATHWAY 0 0.08
Category members GO Category GO:0006796 phosphate-containing compound metabolic process Database 0.07
Category members GO Category GO:0006661 phosphatidylinositol biosynthetic process Database 0.06
Category members GO Category GO:0048488 synaptic vesicle endocytosis Database 0.05
Category members Pathway Pathway_103 REACTOME_PI_METABOLISM 0 0.04
Category members Pathway Pathway_100 REACTOME_PHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_102 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_488 KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM 0 0
Category members Pathway Pathway_538 PID_ERBB1_INTERNALIZATION_PATHWAY 0 0
Category members Disease phenotype Atypical_juvenile_parkinsonism Atypical juvenile parkinsonism Database 0
Category members GO Category GO:0004445 inositol-polyphosphate 5-phosphatase activity Database 0
Category members GO Category GO:0006644 phospholipid metabolic process Database 0
Category members GO Category GO:0006836 neurotransmitter transport Database 0
Category members GO Category GO:0007612 learning Database 0
Category members GO Category GO:0016082 synaptic vesicle priming Database 0
Category members GO Category GO:0030117 membrane coat Database 0
Category members GO Category GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity Database 0
Category members GO Category GO:0043647 inositol phosphate metabolic process Database 0
Category members GO Category GO:0046488 phosphatidylinositol metabolic process Database 0
Category members GO Category GO:0048489 synaptic vesicle transport Database 0


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