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Query: STAMBP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
STAMBP 1 3.339 -1.500 2.650

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
STAMBP Ubiquitylation K180 0.159 _LK(gl)IVQEFGK_
STAMBP Ubiquitylation K107 0.530 -0.048 _AEELK(gl)AELLK_
STAMBP Ubiquitylation K96 -0.832 _LK(gl)EIAFPK_
STAMBP Ubiquitylation K144 -0.041 _NMAIQQELEK(gl)EK_
STAMBP Ubiquitylation K146 -0.693 _NMAIQQELEKEK(gl)QR_

Background Information for STAMBP:





Protein-protein Interactions for STAMBP

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CLTC Cat. description Hein, Mann, Cell 2015
Category members IP bait GTSE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF7 Cat. description Hein, Mann, Cell 2015
Category members IP bait PTPN23 Cat. description Hein, Mann, Cell 2015
Category members IP bait RNASEH2B Cat. description Hein, Mann, Cell 2015
Category members IP bait CDKL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GRAP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GRB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ODF3L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RDH12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC25A41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STAMBPL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in STAMBP

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members JAMM/MPN+_dom IPR000555 1.33
Category members USP8_dimer IPR015063 0.15


Protein complexes (CORUM database) featuring STAMBP

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1784 RNF11-SMURF2-STAMBP complex Database 0


Categories featuring STAMBP

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0004843 ubiquitin-specific protease activity Database 3.28
Category members GO Category GO:0032154 cleavage furrow Database 2.01
Category members GO Category GO:0016579 protein deubiquitination Database 1.32
Category members GO Category GO:0005769 early endosome Database 1.26
Category members Pathway Pathway_666 KEGG_ENDOCYTOSIS 0 1.25
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0000281 mitotic cytokinesis Database 0.77
Category members GO Category GO:0043524 negative regulation of neuron apoptotic process Database 0.66
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0046580 negative regulation of Ras protein signal transduction Database 0.23
Category members Pathway Pathway_538 PID_ERBB1_INTERNALIZATION_PATHWAY 0 0
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0007259 JAK-STAT cascade Database 0
Category members GO Category GO:0008237 metallopeptidase activity Database 0
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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