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negative regulation of Ras protein signal transduction
(GO:0046580)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
PPP2CB 1 2.210 -0.980 0.194 0.044 0.215
PPP2CB 1 2.210 -0.980 0.650 1.189
MFN2 1 0.100 0.320 0.028
STAMBP 1 -1.500 2.650
RASAL2 0 1.030 0.010
MAPKAP1 0 -0.450 1.350
RASA3 0 -0.690 1.590
NF1 0 1.000 -0.500 0.444 -0.190
NUP62 0 1.019 0.665

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
MAPKAP1 Phosphorylation T509 1.075 _RT(ph)SFSFQK_
MAPKAP1 Phosphorylation S510 1.045 1.169 _RTS(ph)FSFQK_
MFN2 Ubiquitylation K84 1.579 0.761 _GYLSK(gl)VR_
MFN2 Ubiquitylation K316 -0.574 _IQK(gl)AQGMPEGGGALAEGFQVR_
MFN2 Ubiquitylation K357 0.235 -0.035 _TK(gl)FEQHTVR_
MFN2 Ubiquitylation K366 -0.376 _AK(gl)QIAEAVR_
MFN2 Ubiquitylation K416 -0.150 0.279 _QLELLAQDYK(gl)LR_
MFN2 Ubiquitylation K420 1.342 0.355 _IK(gl)QITEEVER_
MFN2 Ubiquitylation K463 -0.905 _VYK(gl)NELHR_
MFN2 Ubiquitylation K560 -0.434 _FLGPK(gl)NSRR_
MFN2 Ubiquitylation K719 -0.768 _ENLEQEIAAMNK(gl)K_
MFN2 Ubiquitylation K720 -0.575 _ENLEQEIAAMNKK(gl)_
MFN2 Ubiquitylation K730 -1.137 _KIEVLDSLQSK(gl)AK_
NF1 Ubiquitylation K471 0.218 _MAPSLTFKEK(gl)_
NF1 Phosphorylation S864 -0.458 _SNSGLATYS(ph)PPMGPVSER_
NF1 Phosphorylation T2514 0.076 _GSEGYLAATYPTVGQT(ph)SPR_
NF1 Phosphorylation S2515 0.071 0.316 _GSEGYLAATYPTVGQTS(ph)PR_
NF1 Phosphorylation S2543 0.698 0.655 _S(ph)FDHLISDTK_
NUP62 Phosphorylation S408 1.068 1.163 _ELEDLLS(ph)PLEELVK_
NUP62 Ubiquitylation K445 -0.151 -0.030 _LAENIDAQLK(gl)R_
NUP62 Ubiquitylation K504 0.340 -0.091 _K(gl)VEEVTK(gl)VCEGR_
PPP2CB Ubiquitylation K4 -0.788 -0.378 _(ac)MDDK(gl)AFTK_
PPP2CB Ubiquitylation K4 -0.450 -0.016 _(ac)M(ox)DEK(gl)VFTK_
PPP2CB Ubiquitylation K8 -0.522 _VFTK(gl)ELDQWIEQLNECK_
PPP2CB Ubiquitylation K21 -1.370 _ELDQWVEQLNECK(gl)QLNENQVR_
PPP2CB Ubiquitylation K21 -1.106 _ELDQWIEQLNECK(gl)QLSESQVK_
PPP2CB Ubiquitylation K29 0.211 0.122 _QLSESQVK(gl)SLCEK_
PPP2CB Ubiquitylation K36 -0.455 0.187 _AK(gl)EILTK_
PPP2CB Ubiquitylation K36 -0.455 0.187 _AK(gl)EILTK_
PPP2CB Ubiquitylation K41 -0.049 0.003 _EILTK(gl)ESNVQEVR_
PPP2CB Ubiquitylation K74 -0.316 -0.316 _IGGK(gl)SPDTNYLFMGDYVDR_
RASA3 Ubiquitylation K641 0.708 _LEEESFK(gl)MK_
RASA3 Phosphorylation S809 0.646 0.589 _YGS(ph)QEHPIGDK_
RASAL2 Phosphorylation T132 -1.010 _T(ph)VSVPSEGQFPEYPPEGATK_
RASAL2 Phosphorylation S134 -0.988 -0.690 _TVS(ph)VPSEGQFPEYPPEGATK_
RASAL2 Phosphorylation S159 -0.749 -0.405 _LEVPAERS(ph)PR_
RASAL2 Phosphorylation S164 1.064 -0.013 _S(ph)ISGTSTSEKPNSMDTANTSPFK_
RASAL2 Phosphorylation S237 0.731 1.380 _S(ph)HESLLSPCSTVECLDLGR_
RASAL2 Phosphorylation T761 -0.307 _SLTNPT(ph)PIQQQLR_
STAMBP Ubiquitylation K96 -0.832 _LK(gl)EIAFPK_
STAMBP Ubiquitylation K107 0.530 -0.048 _AEELK(gl)AELLK_
STAMBP Ubiquitylation K144 -0.041 _NMAIQQELEK(gl)EK_
STAMBP Ubiquitylation K146 -0.693 _NMAIQQELEKEK(gl)QR_
STAMBP Ubiquitylation K180 0.159 _LK(gl)IVQEFGK_


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