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Query: MAPKAP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MAPKAP1 0 3.564 -0.450 1.350

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MAPKAP1 Phosphorylation S510 1.045 1.169 _RTS(ph)FSFQK_
MAPKAP1 Phosphorylation T509 1.075 _RT(ph)SFSFQK_

Background Information for MAPKAP1:


Pubmed-MAPKAP1 »
Uniprot-MAPKAP1 »
Biogrid-MAPKAP1 »
ProteomicsDB-MAPKAP1 »

Tumorportal-MAPKAP1 »
COSMIC-MAPKAP1 »
GenomeRNAi-MAPKAP1 »
Genecards-MAPKAP1


Protein-protein Interactions for MAPKAP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CEP170 Cat. description Hein, Mann, Cell 2015
Category members IP bait CTR9 Cat. description Hein, Mann, Cell 2015


Protein Domains in MAPKAP1
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring MAPKAP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3979 mTORC2 complex (mTOR/FRAP1, LST8, mAVO3/RICTOR, SIN1) Database 0.04


Categories featuring MAPKAP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_934 PID_PI3KCI_AKT_PATHWAY 0 2.5
Category members Pathway Pathway_259 REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE 0 2.34
Category members Pathway Pathway_221 REACTOME_SIGNALLING_BY_NGF 0 2.14
Category members Pathway Pathway_660 REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR 0 2.12
Category members Pathway Pathway_724 PID_MTOR_4PATHWAY 0 2
Category members Pathway Pathway_579 PID_ERBB1_DOWNSTREAM_PATHWAY 0 1.97
Category members Pathway Pathway_706 REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR 0 1.96
Category members Pathway Pathway_258 REACTOME_SIGNALING_BY_EGFR_IN_CANCER 0 1.81
Category members Pathway Pathway_265 REACTOME_SIGNALING_BY_FGFR_IN_DISEASE 0 1.42
Category members Pathway Pathway_645 PID_CXCR4_PATHWAY 0 1.42
Category members GO Category GO:0017016 Ras GTPase binding Database 1.28
Category members Pathway Pathway_549 REACTOME_GAB1_SIGNALOSOME 0 1.25
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0048015 phosphatidylinositol-mediated signaling Database 0.98
Category members Pathway Pathway_229 REACTOME_SIGNALING_BY_ERBB2 0 0.68
Category members GO Category GO:0048011 neurotrophin TRK receptor signaling pathway Database 0.63
Category members Pathway Pathway_708 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING 0 0.61
Category members Pathway Pathway_254 REACTOME_SIGNALING_BY_FGFR 0 0.61
Category members Pathway Pathway_599 REACTOME_SIGNALING_BY_SCF_KIT 0 0.48
Category members Pathway Pathway_255 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION 0 0.42
Category members Pathway Pathway_247 REACTOME_SIGNALING_BY_PDGF 0 0.4
Category members Pathway Pathway_590 REACTOME_PI_3K_CASCADE 0 0.37
Category members Pathway Pathway_607 REACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING 0 0.37
Category members GO Category GO:0038095 Fc-epsilon receptor signaling pathway Database 0.36
Category members Pathway Pathway_214 REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR 0 0.33
Category members Pathway Pathway_604 REACTOME_PI3K_AKT_ACTIVATION 0 0.32
Category members Pathway Pathway_614 REACTOME_PI3K_EVENTS_IN_ERBB4_SIGNALING 0 0.32
Category members GO Category GO:0008543 fibroblast growth factor receptor signaling pathway Database 0.29
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0007173 epidermal growth factor receptor signaling pathway Database 0.26
Category members GO Category GO:0016301 kinase activity Database 0.23
Category members GO Category GO:0046580 negative regulation of Ras protein signal transduction Database 0.23
Category members GO Category GO:0070300 phosphatidic acid binding Database 0.19
Category members GO Category GO:0016023 cytoplasmic membrane-bounded vesicle Database 0.17
Category members Pathway Pathway_622 REACTOME_CD28_CO_STIMULATION 0 0.13
Category members GO Category GO:0005546 phosphatidylinositol-4,5-bisphosphate binding Database 0.09
Category members Pathway Pathway_620 REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY 0 0.06
Category members Pathway Pathway_545 REACTOME_SIGNALING_BY_ERBB4 0 0.05
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members GO Category GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding Database 0.04
Category members Pathway Pathway_551 REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING 0 0
Category members Pathway Pathway_655 PID_CXCR3_PATHWAY 0 0
Category members GO Category GO:0031295 T cell costimulation Database 0
Category members GO Category GO:0043325 phosphatidylinositol-3,4-bisphosphate binding Database 0


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