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Results for the Category
REACTOME_SIGNALING_BY_EGFR_IN_CANCER
(Pathway_258)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
RPS27A 4 -1.330 2.560 -0.309 0.131 -0.009
HSP90AA1 3 -0.150 0.150 0.395 1.024 -1.280 0.611 0.460
HSP90AA1 3 0.170 -0.420 0.395 1.024 -1.280 0.611 0.460
UBA52 3 -1.260 2.180 -0.309 0.131 -0.009
UBA52 3 -1.260 2.180
ITPR3 2 -0.190 -0.500 1.489 1.835
GSK3A 2 -1.420 1.510 -1.128 1.091
GSK3A 2 -1.420 1.510
AKT3 2 0.580 -0.030 -0.194
AKT3 2 0.580 -0.030
FOXO3 2 -0.410 -0.120
CLTA 2 -0.050 0.210
CLTA 2 -0.050 0.210 -1.163 -0.046
TSC2 1 0.810 -0.710
TSC2 1 0.810 -0.710 -0.715
PRKAR1A 1 -0.550 0.230
PRKAR1A 1 -0.550 0.230
PLCG1 1 -0.170 0.000
RAF1 1 2.020 -1.230
KRAS 1 -0.510 0.620 1.031 0.887
KRAS 1 -0.510 0.620 0.246 -0.346
ADCY3 1 -0.850 1.180
CALM2 1 -0.690 0.700 1.911
CALM2 1 -0.690 0.700 0.877 -4.680
CALM3 1 -0.190 0.120 1.911
CALM3 1 -0.190 0.120 0.877 -4.680
RICTOR 1 -0.330 0.710
RICTOR 1 -0.270 0.570
MAP2K1 1 -1.590 2.780
PRKAR1B 1 0.660 -0.470
PRKAR1B 1 0.660 -0.470
CALM1 1 -0.440 0.360 1.911
CALM1 1 -0.440 0.360 0.877 -4.680
NRAS 1 1.810 -0.720 0.246 -0.346
BAD 0 -0.660 1.190
PRKAR2B 0 -0.290 0.380
AP2B1 0 0.890 -0.970
AP2B1 0 0.890 -0.970 -0.267 0.203 0.287 0.311 0.233
AP2S1 0 -0.210 0.500 -0.049 0.539 0.830 0.375
EPN1 0 0.000 -0.210 0.286 0.676 0.159
CDC42 0 -0.170 0.490 -0.597 -1.527 -1.013
CDC42 0 1.240 -0.940 -0.597 -1.527 -1.013
PRKACA 0 0.380 -0.680 -1.005 -0.697 0.234 0.487
PAG1 0 -0.550 1.760
EPS15 0 0.580 -0.640
EPS15 0 0.580 -0.640
MAPK3 0
CSK 0 1.200 -0.960 -1.211
CSK 0 1.200 -0.960
AKT2 0 -1.420 2.210 -0.194
CDC37 0 -1.030 1.190 0.339 0.690 1.087
SH3GL2 0 0.310 -0.450
GAB1 0 1.950 -1.110
PRKAR2A 0 -0.530 1.080 0.026 -1.317 -0.866 0.783 0.007
PRKAR2A 0 -0.530 1.080
STAM2 0 -0.510 0.650
SOS1 0 0.500 -0.620 -0.570
CREB1 0 1.080 -0.800 -1.027
MAPKAP1 0 -0.450 1.350
ADCY7 0
PIK3CA 0
ITPR2 0 -1.020 0.610 0.952 0.981
CDKN1A 0 1.080 -0.750
MAP2K2 0 -0.610 0.080
MAP2K2 0 -0.610 0.080
EPS15L1 0 0.060 -0.480 -0.187 0.065
MDM2 0 -0.210 0.080
ADAM10 0 1.400 -1.040 -0.111 0.009
PDPK1 0 0.050 -0.440
CLTC 0 0.350 -0.220 -0.538 -0.243 -0.478 0.375 0.284
AKT1 0 -0.050 0.700
AKT1 0 0.860 -0.040
PRKACB 0 1.740 -1.200 -1.064
PRKACB 0 1.740 -1.200 -1.005 -0.697 0.234 0.487
LRIG1 0 -1.220 1.350
PIK3R1 0 1.910 -1.220 -0.441 0.147
EGFR 0 -0.580 0.520 0.513 0.090
SH3KBP1 0 -0.400 -0.020 -0.522
ADAM17 0 0.520 -0.620
CAMK4 0 0.780 -0.790
PRKCA 0 0.750 -0.690 0.349 0.585
PRKCA 0 0.750 -0.690
AP2M1 0 -1.250 2.200 -0.363 0.794 -0.187 0.544 0.370
AP2M1 0 -1.250 2.200
ADCY9 0 -0.910 0.930
PRKCD 0 0.250 0.070 0.578 0.427
YWHAB 0 0.628 -0.543
YWHAB 0 0.507 0.271 0.503
MLST8 0 -0.170 0.220
CDK1 0 -0.370 0.080 -0.202 -0.884 -0.107 -0.097 -0.501
ADRBK1 0 -0.390 0.360
ADRBK1 0 -0.340 0.480
ADCY6 0 -0.720 0.740
HRAS 0 1.470 -0.520
RPS6KB2 0 -1.260 2.030
GRB2 0 -0.240 0.300 -1.021 0.057 0.906
AP2A2 0 -1.330 2.130 1.006 0.165 0.468 0.244 0.392
HGS 0 0.020 0.300 -0.211 0.737 0.264
AP2A1 0 0.510 -1.060 0.414 0.086 0.168 -0.002 0.179
SRC 0 0.050 0.470 -0.031
MTOR 0 -0.680 0.150 0.757 0.074 0.101
AKT1S1 0 -0.070 -0.260
CHUK 0 -0.480

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ADAM10 Ubiquitylation K721 -2.406 _LPPPKPLPGTLK(gl)R_
ADAM17 Phosphorylation S791 -0.594 0.152 _S(ph)FEDLTDHPVTR_
ADCY3 Ubiquitylation K406 -0.885 _TK(gl)TGVDMR_
ADCY3 Ubiquitylation K628 0.051 _YSVEK(gl)EK_
ADCY3 Ubiquitylation K879 0.818 2.820 _IEVHDQK(gl)ER_
ADCY3 Ubiquitylation K1047 -1.036 _IGMNK(gl)GGVLAGVIGAR_
ADCY6 Phosphorylation S54 -1.434 -1.374 _DAEPPS(ph)PTPAGPPR_
ADCY6 Ubiquitylation K80 0.473 0.937 _GK(gl)ELGLR_
ADCY6 Ubiquitylation K568 1.007 0.799 _AMLAK(gl)LQR_
ADCY6 Phosphorylation S576 -0.020 _ANS(ph)MEGLMPR_
ADCY7 Ubiquitylation K477 0.660 _GDAALK(gl)MR_
ADCY9 Ubiquitylation K35 0.400 _INPK(gl)QLSSNSHPK_
ADCY9 Ubiquitylation K564 0.874 0.253 _LGQSVVADQLK(gl)GLK_
ADCY9 Ubiquitylation K622 0.176 0.287 _GQGTASSGNVSDLAQTVK(gl)TFDNLK_
ADCY9 Ubiquitylation K628 0.266 _TFDNLK(gl)TCPSCGITFAPK_
ADCY9 Ubiquitylation K699 1.085 _LTNSQTSLCEILQEK(gl)GR_
ADCY9 Ubiquitylation K1218 1.351 1.067 _VLSK(gl)MGYDFDYR_
ADRBK1 Phosphorylation S670 1.038 0.924 _NKPRS(ph)PVVELSK_
ADRBK1 Phosphorylation S676 1.113 _NKPRSPVVELS(ph)K_
AKT1 Phosphorylation S124 0.252 0.311 _SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1 Phosphorylation S126 -0.241 _SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1 Ubiquitylation K301 0.988 _EGIK(gl)DGATMK_
AKT1S1 Phosphorylation S88 -2.758 -2.516 _AATAARPPAPPPAPQPPS(ph)PTPS(ph)PPRPTLAR_
AKT1S1 Phosphorylation S92 -3.077 -3.065 _AATAARPPAPPPAPQPPS(ph)PTPS(ph)PPRPTLAR_
AKT1S1 Phosphorylation T97 -3.450 _AATAARPPAPPPAPQPPS(ph)PTPSPPRPT(ph)LAR_
AKT1S1 Phosphorylation S183 -0.539 -0.207 _S(ph)LPVSVPVWGFK_
AKT1S1 Phosphorylation S203 -0.783 -0.726 _SS(ph)DEENGPPSS(ph)PDLDR_
AKT1S1 Phosphorylation S211 -0.801 -1.311 _SS(ph)DEENGPPS(ph)SPDLDR_
AKT1S1 Phosphorylation S212 0.721 -1.311 _SS(ph)DEENGPPSS(ph)PDLDR_
AKT1S1 Phosphorylation T246 0.502 0.358 _LNT(ph)SDFQK_
AKT2 Ubiquitylation K14 0.306 0.070 _EGWLHK(gl)R_
AKT2 Ubiquitylation K111 1.082 _AIQMVANSLK(gl)QR_
AKT2 Ubiquitylation K160 0.251 _LLGK(gl)GTFGK_
AKT2 Phosphorylation T451 -0.091 -0.612 _YFDDEFTAQSITIT(ph)PPDRYDSLGLLELDQR_
AKT2 Phosphorylation Y456 -0.265 _YFDDEFTAQSITITPPDRY(ph)DSLGLLELDQR_
AKT3 Ubiquitylation K14 0.306 0.070 _EGWLHK(gl)R_
AKT3 Ubiquitylation K14 4.941 5.277 _EGWVQK(gl)R_
AKT3 Ubiquitylation K111 1.082 _AIQMVANSLK(gl)QR_
AKT3 Phosphorylation S120 1.097 _MNCS(ph)PTSQIDNIGEEEMDASTTHHK_
AKT3 Ubiquitylation K160 0.251 _LLGK(gl)GTFGK_
AKT3 Phosphorylation T451 -0.091 -0.612 _YFDDEFTAQSITIT(ph)PPDRYDSLGLLELDQR_
AKT3 Phosphorylation Y456 -0.265 _YFDDEFTAQSITITPPDRY(ph)DSLGLLELDQR_
AP2A1 Phosphorylation S655 -1.574 _DPSSNDINGGM(ox)EPTPSTVSTPS(ph)PSADLLGLR_
AP2A1 Ubiquitylation K880 -0.136 _WK(gl)QLSLPQQEAQK_
AP2A2 Ubiquitylation K6 -0.477 0.972 _PAVSK(gl)GDGMR_
AP2A2 Ubiquitylation K616 -0.123 _ESSILAKLK(gl)_
AP2A2 Ubiquitylation K631 -0.267 -0.317 _KGPSTVTDLEDTK(gl)R_
AP2B1 Ubiquitylation K5 0.145 0.310 _(ac)TDSK(gl)YFTTNK_
AP2B1 Ubiquitylation K12 0.255 _K(gl)GEIFELK_
AP2B1 Ubiquitylation K117 -0.547 _VDK(gl)ITEYLCEPLRK_
AP2B1 Ubiquitylation K131 0.324 -0.027 _CLK(gl)DEDPYVRK_
AP2B1 Ubiquitylation K733 -0.273 _AVWLPAVK(gl)AK_
AP2B1 Ubiquitylation K735 -0.839 -0.273 _AVWLPAVKAK(gl)_
AP2M1 Ubiquitylation K249 0.386 0.460 _IVIEK(gl)QGK_
AP2M1 Ubiquitylation K263 -0.058 -0.236 _SGK(gl)QSIAIDDCTFHQCVR_
AP2M1 Ubiquitylation K281 -0.401 0.214 _LSK(gl)FDSER_
AP2M1 Ubiquitylation K306 -2.014 -0.836 _TTK(gl)DIILPFR_
AP2M1 Ubiquitylation K337 -1.115 _SNFK(gl)PSLLAQK_
AP2M1 Ubiquitylation K364 -1.253 _IPTPLNTSGVQVICMK(gl)GK_
AP2S1 Ubiquitylation K45 -1.058 -0.297 _DAK(gl)HTNFVEFR_
AP2S1 Ubiquitylation K130 -1.793 0.099 _ETSQTK(gl)VLK_
BAD Phosphorylation S74 -0.904 -0.452 _HS(ph)SYPAGTEDDEGM(ox)GEEPSPFR_
BAD Phosphorylation S75 -0.914 -0.660 _HSS(ph)YPAGTEDDEGMGEEPSPFR_
BAD Phosphorylation S97 0.056 _S(ph)RSAPPNLWAAQR_
BAD Phosphorylation S99 -0.299 0.161 _S(ph)APPNLWAAQR_
BAD Phosphorylation S118 1.277 1.089 _RM(ox)S(ph)DEFVDSFKK_
CALM1 Ubiquitylation K78 0.061 _DGDGTITTK(gl)ELGTVMR_
CALM1 Ubiquitylation K142 0.922 _VFDK(gl)DGNGYISAAELR_
CALM2 Ubiquitylation K78 0.061 _DGDGTITTK(gl)ELGTVMR_
CALM2 Ubiquitylation K142 0.922 _VFDK(gl)DGNGYISAAELR_
CALM3 Ubiquitylation K78 0.061 _DGDGTITTK(gl)ELGTVMR_
CALM3 Ubiquitylation K142 0.922 _VFDK(gl)DGNGYISAAELR_
CAMK4 Phosphorylation S360 -0.256 0.086 _DPS(ph)PIQDGNEDMK_
CDC37 Phosphorylation S5 0.600 0.297 _(ac)VDYS(ph)VWDHIEVSDDEDETHPNIDTASLFR_
CDC37 Phosphorylation S13 0.017 0.075 _(ac)VDYSVWDHIEVS(ph)DDEDETHPNIDTASLFR_
CDC37 Ubiquitylation K45 -0.075 _MEQFQK(gl)EKEELDR_
CDC37 Ubiquitylation K69 0.281 _LK(gl)ELEVAEGGK_
CDC37 Ubiquitylation K132 -0.873 _SMVNTK(gl)PEKTEEDSEEVR_
CDC37 Ubiquitylation K157 0.330 _TFVEKYEK(gl)QIK_
CDC37 Ubiquitylation K330 -0.426 0.035 _MDPTDAK(gl)YHMQR_
CDC37 Ubiquitylation K352 -1.772 _ASEAK(gl)EGEEAGPGDPLLEAVPK_
CDC42 Ubiquitylation K173 -1.839 _DDPSTIEK(gl)LAK_
CDC42 Ubiquitylation K178 -0.801 -0.716 _NK(gl)QKPITPETAEK_
CDC42 Ubiquitylation K180 -1.806 _QK(gl)PITPETAEK(gl)LAR_
CDC42 Ubiquitylation K189 -1.082 _QKPITPETAEK(gl)LAR_
CDC42 Ubiquitylation K198 0.550 1.159 _AVK(gl)YVECSALTQK_
CDC42 Ubiquitylation K208 -0.937 0.038 _YVECSALTQK(gl)GLK_
CDC42 Ubiquitylation K228 -2.488 _NVFDEAILAALEPPEPK(gl)K_
CDC42 Ubiquitylation K229 -1.254 _NVFDEAILAALEPPEPKK(gl)_
CDK1 Ubiquitylation K6 0.011 -0.784 _(ac)M(ox)EDYTK(gl)IEK_
CDK1 Ubiquitylation K20 -0.327 -0.270 _IGEGTYGVVYK(gl)GR_
CDK1 Ubiquitylation K33 0.736 0.239 _TTGQVVAMK(gl)K_
CDK1 Ubiquitylation K34 -0.306 _TTGQVVAMKK(gl)_
CDK1 Ubiquitylation K58 0.312 -0.262 _EISLLK(gl)ELR_
CDK1 Ubiquitylation K136 -0.468 _DLK(gl)PQNLLIDDK(gl)GTIK_
CDK1 Ubiquitylation K145 0.161 -0.954 _DLKPQNLLIDDK(gl)GTIK_
CDK1 Ubiquitylation K149 -0.038 _GTIK(gl)LADFGLAR_
CDK1 Ubiquitylation K251 -0.047 -1.236 _WK(gl)PGSLASHVK_
CDK1 Ubiquitylation K280 0.179 -1.210 _MLIYDPAK(gl)R_
CDKN1A Ubiquitylation K188 -2.505 -1.077 _QTSMTDFYHSK(gl)R_
CHUK Ubiquitylation K296 -1.637 _GGPVDLTLK(gl)QPR_
CLTA Phosphorylation S105 1.262 1.599 _LQS(ph)EPESIRK_
CLTA Ubiquitylation K223 -0.282 0.457 _LCDFNPK(gl)SSK_
CLTA Ubiquitylation K226 -0.199 1.848 _LCDFNPKSSK(gl)_
CLTA Ubiquitylation K242 0.149 _SVLISLK(gl)QAPLVH_
CLTC Ubiquitylation K83 0.714 _VIALK(gl)AGK_
CLTC Ubiquitylation K86 0.631 _VIALKAGK(gl)_
CLTC Ubiquitylation K389 -1.051 -0.085 _VAANAPK(gl)GILR_
CLTC Phosphorylation T394 -0.123 0.181 _GILRT(ph)PDTIRR_
CLTC Ubiquitylation K506 0.267 _IVLYAK(gl)K_
CLTC Ubiquitylation K507 0.050 0.267 _IVLYAKK(gl)_
CLTC Ubiquitylation K619 -0.177 0.475 _AHIAQLCEK(gl)AGLLQR_
CLTC Ubiquitylation K737 -0.435 -0.298 _YIQAACK(gl)TGQIK_
CLTC Ubiquitylation K742 0.005 0.082 _TGQIK(gl)EVER_
CLTC Ubiquitylation K851 -0.859 _GQFSTDELVAEVEK(gl)R_
CLTC Ubiquitylation K911 -1.282 _YCEK(gl)RDPHLACVAYER_
CLTC Ubiquitylation K1118 -0.674 -0.765 _AQLQK(gl)GMVK_
CLTC Ubiquitylation K1209 -0.791 _CYDEK(gl)MYDAAK_
CLTC Ubiquitylation K1443 -2.089 -0.019 _VK(gl)QLPLVKPYLR_
CLTC Ubiquitylation K1449 -2.307 _QLPLVK(gl)PYLR_
CLTC Ubiquitylation K1516 -0.990 _IAAYLFK(gl)GNNR_
CLTC Ubiquitylation K1609 -0.714 _EYLTK(gl)VDKLDASESLR_
CREB1 Phosphorylation S271 -0.979 -1.450 _TAPTSTIAPGVVM(ox)ASS(ph)PALPTQPAEEAAR_
CREB1 Ubiquitylation K333 1.343 _ALK(gl)DLYCHK_
CSK Ubiquitylation K196 -0.133 _SGWALNMKELK(gl)_
EGFR Phosphorylation T693 0.486 -0.139 _ELVEPLT(ph)PSGEAPNQALLR_
EGFR Phosphorylation S991 -0.041 _MHLPS(ph)PTDSNFYR_
EPN1 Ubiquitylation K97 -0.214 0.731 _VSQQCK(gl)ENMYAVQTLK_
EPN1 Ubiquitylation K107 -0.288 1.227 _ENMYAVQTLK(gl)DFQYVDR_
EPN1 Ubiquitylation K117 0.237 _DFQYVDRDGK(gl)DQGVNVR_
EPN1 Ubiquitylation K128 0.126 _AK(gl)QLVALLRDEDR_
EPN1 Phosphorylation S417 0.164 _TALPTS(ph)GSSAGELELLAGEVPAR_
EPN1 Phosphorylation S420 -0.776 -0.436 _TALPTSGSS(ph)AGELELLAGEVPAR_
EPN1 Phosphorylation S435 0.801 0.890 _S(ph)PGAFDMSGVR_
EPN1 Phosphorylation T470 -1.386 -1.782 _T(ph)PESFLGPNAALVDLDSLVSRPGPTPPGAK_
EPN1 Phosphorylation S473 -0.700 -0.430 _KTPES(ph)FLGPNAALVDLDSLVSR_
EPS15 Phosphorylation S108 -1.380 -0.251 _FHDTSS(ph)PLLISGTSAAELPWAVKPEDK_
EPS15 Phosphorylation S324 1.499 1.080 _NIIGSS(ph)PVADFSAIK_
EPS15 Phosphorylation S428 -0.224 -0.557 _S(ph)SPELLPSGVTDENEVTTAVTEK_
EPS15 Phosphorylation S429 -0.224 -0.308 _S(ph)SPELLPSGVTDENEVTTAVTEK_
EPS15 Ubiquitylation K620 0.143 0.541 _SATSSSVSNVVITK(gl)NVFEETSVK_
EPS15 Ubiquitylation K654 -2.207 -1.253 _IGTPTRPCPLPPGK(gl)R_
EPS15 Phosphorylation S662 1.046 0.458 _SINKLDS(ph)PDPFK_
EPS15 Phosphorylation S814 -0.764 -0.870 _LNDPFQPFPGNDS(ph)PKEKDPEIFCDPFTSATTTTNK_
EPS15L1 Phosphorylation S107 -0.485 -0.667 _FHDTS(ph)SPLM(ox)VTPPSAEAHWAVR_
EPS15L1 Phosphorylation S229 -1.124 -1.213 _KTVFPGAVPVLPAS(ph)PPPKDSLR_
EPS15L1 Phosphorylation S255 0.126 0.287 _STPSHGSVSSLNSTGSLS(ph)PK_
EPS15L1 Ubiquitylation K400 0.435 _EK(gl)YSLEQDIR_
EPS15L1 Ubiquitylation K492 -0.067 0.278 _TQIQSQESDLK(gl)SQEDDLNR_
EPS15L1 Ubiquitylation K531 0.195 0.973 _VQLETIIK(gl)SLK_
EPS15L1 Ubiquitylation K534 -0.080 0.668 _SLK(gl)STQDEINQAR_
EPS15L1 Ubiquitylation K546 -0.181 0.567 _SK(gl)LSQLHESR_
EPS15L1 Phosphorylation S575 0.556 _SLEQYDQVLDGAHGAS(ph)LTDLANLSEGVSLAER_
EPS15L1 Phosphorylation T577 0.556 _SLEQYDQVLDGAHGAS(ph)LTDLANLSEGVSLAER_
EPS15L1 Ubiquitylation K604 -0.465 0.502 _GSFGAMDDPFKNK(gl)_
EPS15L1 Phosphorylation T612 0.698 _ALLFSNNT(ph)QELHPDPFQTEDPFK_
EPS15L1 Ubiquitylation K679 0.297 0.644 _GSATDDFFK(gl)K_
EPS15L1 Ubiquitylation K683 -0.669 -0.149 _QTK(gl)NDPFTSDPFTK_
EPS15L1 Ubiquitylation K694 -2.706 -1.303 _NDPFTSDPFTK(gl)NPSLPSK_
EPS15L1 Ubiquitylation K701 -2.391 _NPSLPSK(gl)LDPFESSDPFSSSSVSSK_
EPS15L1 Phosphorylation S804 -1.633 _STPVSQLGS(ph)ADFPEAPDPFQPLGADSGDPFQSK_
FOXO3 Phosphorylation S12 -1.324 _(ac)AEAPASPAPLS(ph)PLEVELDPEFEPQSRPR_
FOXO3 Phosphorylation S253 2.510 _AVS(ph)MDNSNKYTK_
FOXO3 Phosphorylation S284 4.138 6.011 _AALQTAPESADDS(ph)PSQLSK_
FOXO3 Phosphorylation S421 1.295 _GS(ph)GLGSPTSSFNSTVFGPSSLNSLR_
FOXO3 Phosphorylation S425 1.471 _GSGLGS(ph)PTSSFNSTVFGPSSLNSLR_
GAB1 Phosphorylation S266 0.756 0.551 _SYS(ph)HDVLPK_
GAB1 Phosphorylation S367 0.230 0.176 _TAS(ph)DTDSSYCIPTAGMS(ph)PSR_
GAB1 Phosphorylation T369 -0.352 _TASDT(ph)DSSYCIPTAGMS(ph)PSR_
GAB1 Phosphorylation S381 -0.481 0.139 _TASDTDSSYCIPTAGM(ox)S(ph)PSR_
GAB1 Phosphorylation S401 0.266 0.788 _DAS(ph)SQDCYDIPR_
GAB1 Phosphorylation S402 0.328 0.633 _DASS(ph)QDCYDIPR_
GAB1 Phosphorylation S419 0.540 _SSS(ph)LEGFHNHFK_
GRB2 Ubiquitylation K10 0.146 _YDFK(gl)ATADDELSFK_
GRB2 Ubiquitylation K20 -0.078 _ATADDELSFK(gl)R_
GRB2 Ubiquitylation K69 -0.362 0.641 _AK(gl)AEEMLSK_
GRB2 Ubiquitylation K76 0.754 _AEEMLSK(gl)QR_
GRB2 Ubiquitylation K109 0.381 -0.002 _FGNDVQHFK(gl)VLR_
GSK3A Phosphorylation S9 -0.483 0.010 _TTS(ph)FAESCKPVQQPSAFGSMK_
GSK3A Phosphorylation S21 -0.406 _TSS(ph)FAEPGGGGGGGGGGPGGSASGPGGTGGGK_
GSK3A Ubiquitylation K85 -0.204 _LCDSGELVAIK(gl)K_
GSK3A Ubiquitylation K86 -0.204 _LCDSGELVAIK(gl)K_
GSK3A Ubiquitylation K148 0.396 _ELVAIK(gl)K_
GSK3A Phosphorylation S215 0.296 0.477 _GEPNVS(ph)YICSR_
GSK3A Phosphorylation Y216 0.356 0.376 _GEPNVSY(ph)ICSR_
GSK3A Phosphorylation T390 2.800 2.527 _IQAAAST(ph)PTNATAASDANTGDR_
HGS Ubiquitylation K126 0.088 0.464 _YK(gl)VVQDTYQIMK_
HGS Ubiquitylation K192 0.015 0.751 _ACGQIFCGK(gl)CSSK_
HGS Ubiquitylation K202 -0.163 0.558 _YSTIPK(gl)FGIEK_
HGS Ubiquitylation K207 -0.193 0.798 _FGIEK(gl)EVR_
HGS Ubiquitylation K283 -0.826 -0.270 _QK(gl)STYTSYPK_
HGS Ubiquitylation K337 0.097 _NYWEK(gl)KQEEAR_
HGS Ubiquitylation K473 -0.154 _LYYEGLQDK(gl)LAQIR_
HGS Ubiquitylation K513 -0.289 _QIQLAQK(gl)LEIMR_
HGS Ubiquitylation K520 0.211 1.230 _QK(gl)KQEYLEVQR_
HGS Ubiquitylation K521 -1.344 1.230 _K(gl)QEYLEVQR_
HGS Ubiquitylation K551 -0.260 0.554 _LEQQK(gl)QTVQM(ox)R_
HRAS Ubiquitylation K170 -1.005 _K(gl)LNPPDESGPGCMSCK_
HSP90AA1 Ubiquitylation K69 0.820 -0.090 _YESLTDPSK(gl)LDSGK_
HSP90AA1 Ubiquitylation K74 0.543 _LDSGK(gl)ELHINLIPNKQDR_
HSP90AA1 Ubiquitylation K112 1.304 1.601 _ADLINNLGTIAK(gl)SGTK_
HSP90AA1 Ubiquitylation K185 0.963 _GTK(gl)VILHLK_
HSP90AA1 Ubiquitylation K208 1.745 _IKEIVK(gl)K_
HSP90AA1 Phosphorylation S231 2.338 0.649 _DKEVS(ph)DDEAEEK_
HSP90AA1 Phosphorylation S263 0.095 0.173 _ESEDKPEIEDVGS(ph)DEEEEKK_
HSP90AA1 Ubiquitylation K281 1.267 _IK(gl)EKYIDQEELNK_
HSP90AA1 Ubiquitylation K283 1.442 1.226 _EK(gl)YIDQEELNK_
HSP90AA1 Ubiquitylation K292 -0.237 0.506 _YIDQEELNK(gl)TKPIWTR_
HSP90AA1 Ubiquitylation K294 0.315 8.646 _TK(gl)PIWTR_
HSP90AA1 Ubiquitylation K362 0.969 0.946 _NNIK(gl)LYVR_
HSP90AA1 Ubiquitylation K407 0.827 1.121 _EMLQQSK(gl)ILK_
HSP90AA1 Ubiquitylation K443 0.820 0.951 _FYEQFSK(gl)NIK_
HSP90AA1 Ubiquitylation K446 0.314 1.126 _NIK(gl)LGIHEDSQNR_
HSP90AA1 Ubiquitylation K478 0.799 1.624 _YYTSASGDEM(ox)VSLK(gl)DYCTR_
HSP90AA1 Ubiquitylation K539 0.353 1.775 _EFEGK(gl)TLVSVTK_
HSP90AA1 Ubiquitylation K559 -0.316 _EGLELPEDEEEKK(gl)K_
HSP90AA1 Ubiquitylation K565 0.903 _K(gl)TKFENLCK_
HSP90AA1 Ubiquitylation K567 0.710 _TK(gl)FENLCK_
HSP90AA1 Ubiquitylation K576 0.874 _IMK(gl)DILEK_
HSP90AA1 Ubiquitylation K581 0.540 0.738 _DILEK(gl)KVEK_
HSP90AA1 Ubiquitylation K582 0.063 0.470 _K(gl)VEKVVVSNR_
HSP90AA1 Ubiquitylation K615 0.715 0.751 _IMK(gl)AQALR_
HSP90AA1 Ubiquitylation K631 0.361 0.974 _DNSTMGYMAAK(gl)K_
ITPR2 Ubiquitylation K909 -0.247 _LSK(gl)FQDGGNNVMR_
ITPR2 Phosphorylation S1160 0.443 0.895 _GGEEPIEESNILS(ph)PVQDGTK_
ITPR3 Ubiquitylation K529 1.377 _EK(gl)GGEGPLVR_
ITPR3 Phosphorylation S934 0.318 -0.802 _KQS(ph)VFSAPSLSAGASAAEPLDR_
ITPR3 Phosphorylation S937 -0.026 _KQSVFS(ph)APSLSAGASAAEPLDR_
ITPR3 Ubiquitylation K1534 -0.220 _TLAMVAK(gl)GR_
ITPR3 Phosphorylation S1832 0.650 0.560 _VAS(ph)FSIPGSSSR_
ITPR3 Ubiquitylation K2597 -0.819 _NK(gl)NLDWFPR_
ITPR3 Ubiquitylation K2628 -0.010 _ILQDK(gl)LNSTMK_
ITPR3 Phosphorylation S2670 1.132 1.555 _LGFVDVQNCIS(ph)R_
KRAS Ubiquitylation K128 1.528 1.433 _TVDTK(gl)QAHELAK_
KRAS Ubiquitylation K235 0.591 0.087 _TVDTK(gl)QAQDLAR_
KRAS Ubiquitylation K254 -0.450 -0.156 _SYGIPFIETSAK(gl)TR_
LRIG1 Phosphorylation S1069 -0.682 _ACDAS(ph)PESTPLTGQLPGK_
MAP2K1 Ubiquitylation K192 -0.205 -0.241 _DVK(gl)PSNILVNSR_
MAP2K1 Phosphorylation S385 0.066 _RSDAEEVDFAGWLCSTIGLNQPS(ph)TPTHAAGV_
MAP2K1 Phosphorylation T386 0.377 _RSDAEEVDFAGWLCSTIGLNQPST(ph)PTHAAGV_
MAP2K2 Phosphorylation S23 0.873 0.258 _RKPVLPALTINPTIAEGPS(ph)PTSEGASEANLVDLQK_
MAP2K2 Phosphorylation T25 0.439 _RKPVLPALTINPTIAEGPSPT(ph)SEGASEANLVDLQK_
MAP2K2 Ubiquitylation K192 -0.205 -0.241 _DVK(gl)PSNILVNSR_
MAP2K2 Phosphorylation S293 -0.361 _ELEAIFGRPVVDGEEGEPHS(ph)ISPR_
MAP2K2 Phosphorylation S295 -0.234 0.026 _ELEAIFGRPVVDGEEGEPHSIS(ph)PR_
MAP2K2 Phosphorylation T394 0.570 0.158 _LNQPGT(ph)PTR_
MAPK3 Phosphorylation Y204 -0.807 -2.487 _IADPEHDHTGFLTEY(ph)VATR_
MAPK3 Ubiquitylation K289 -0.608 _NYLQSLPSKTK(gl)_
MAPKAP1 Phosphorylation T509 1.075 _RT(ph)SFSFQK_
MAPKAP1 Phosphorylation S510 1.045 1.169 _RTS(ph)FSFQK_
MDM2 Phosphorylation S166 0.576 1.068 _AIS(ph)ETEENSDELSGER_
MDM2 Ubiquitylation K334 -0.872 _ENWLPEDK(gl)GK_
MDM2 Ubiquitylation K336 -0.872 _ENWLPEDK(gl)GK_
MDM2 Ubiquitylation K363 0.883 _LENSTQAEEGFDVPDCK(gl)K_
MDM2 Ubiquitylation K364 0.883 _LENSTQAEEGFDVPDCK(gl)K_
MDM2 Ubiquitylation K473 0.806 _NK(gl)PCPVCR_
MLST8 Phosphorylation T3 -0.481 _(ac)MNT(ph)SPGTVGSDPVILATAGYDHTVR_
MLST8 Ubiquitylation K245 -0.114 0.462 _FSPDSTLLATCSADQTCK(gl)IWR_
MTOR Ubiquitylation K309 -0.762 0.065 _DLMGFGTK(gl)PR_
MTOR Ubiquitylation K1257 -1.167 -0.901 _SGQGDALASGPVETGPMKK(gl)_
MTOR Ubiquitylation K1395 -1.255 _AYAK(gl)ALHYK_
MTOR Ubiquitylation K2066 -1.004 _GPQTLK(gl)ETSFNQAYGR_
MTOR Ubiquitylation K2166 -1.304 _IQSIAPSLQVITSK(gl)QRPR_
MTOR Phosphorylation T2471 0.329 _KT(ph)GTTVPESIHSFIGDGLVKPEALNK_
NRAS Ubiquitylation K128 1.528 1.433 _TVDTK(gl)QAHELAK_
PAG1 Phosphorylation S288 0.574 0.875 _EGGEAEESATDTTS(ph)ETNK_
PDPK1 Phosphorylation S241 0.358 0.361 _ANS(ph)FVGTAQYVSPELLTEK_
PDPK1 Ubiquitylation K257 0.571 -0.234 _ANSFVGTAQYVSPELLTEK(gl)SACK_
PIK3CA Ubiquitylation K864 0.390 0.588 _NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA Ubiquitylation K868 0.204 0.651 _NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA Ubiquitylation K974 -0.273 _GAQECTK(gl)TREFER_
PLCG1 Ubiquitylation K300 8.031 _DLK(gl)NMLSQVNYR_
PLCG1 Ubiquitylation K348 -0.219 _SLMYSAQK(gl)TMDLPFLEASTLR_
PLCG1 Ubiquitylation K552 -0.355 _NMAQYFK(gl)K_
PLCG1 Ubiquitylation K553 -0.355 _NMAQYFK(gl)K_
PLCG1 Ubiquitylation K1063 0.864 0.355 _LTEGK(gl)IMER_
PLCG1 Phosphorylation S1370 0.475 0.515 _AREGS(ph)FESR_
PRKACA Ubiquitylation K30 -0.143 _AKEDFLKK(gl)_
PRKACA Ubiquitylation K93 0.839 0.714 _QIEHTLNEK(gl)R_
PRKACB Ubiquitylation K30 -0.143 _AKEDFLKK(gl)_
PRKACB Ubiquitylation K93 0.839 0.714 _QIEHTLNEK(gl)R_
PRKACB Phosphorylation T243 -0.835 _T(ph)WTLCGTPEYLAPEIILSK_
PRKACB Phosphorylation T245 -0.116 -0.102 _TWT(ph)LCGTPEYLAPEIILSK_
PRKAR1A Ubiquitylation K63 -1.895 _LEKEEAK(gl)QIQNLQK_
PRKAR1A Ubiquitylation K70 -0.869 0.073 _QIQNLQK(gl)AGTR_
PRKAR1A Phosphorylation S83 -0.969 -0.776 _EDEIS(ph)PPPPNPVVK_
PRKAR1A Ubiquitylation K92 -3.269 -2.395 _TDSREDEISPPPPNPVVK(gl)GR_
PRKAR1A Ubiquitylation K222 0.412 0.536 _TNVK(gl)LWGIDR_
PRKAR1A Ubiquitylation K244 -0.384 3.721 _K(gl)MYEEFLSK_
PRKAR1A Ubiquitylation K261 -0.886 _VSILESLDK(gl)WER_
PRKAR1A Ubiquitylation K346 0.329 _GPLK(gl)CVK_
PRKAR1A Ubiquitylation K349 -0.425 -0.103 _CVK(gl)LDRPR_
PRKAR1A Ubiquitylation K367 -0.939 0.044 _VLGPCSDILK(gl)R_
PRKAR1B Phosphorylation S3 0.185 0.343 _(ac)AS(ph)PPACPSEEDESLKGCELYVQLHGIQQVLK_
PRKAR1B Ubiquitylation K244 -0.384 3.721 _K(gl)MYEEFLSK_
PRKAR1B Ubiquitylation K346 0.329 _GPLK(gl)CVK_
PRKAR1B Ubiquitylation K349 -0.425 -0.103 _CVK(gl)LDRPR_
PRKAR2A Phosphorylation S99 0.020 0.056 _RVS(ph)VCAETYNPDEEEEDTDPR_
PRKAR2A Phosphorylation T104 -0.175 _RVSVCAET(ph)YNPDEEEEDTDPR_
PRKAR2A Ubiquitylation K359 0.640 _GQYFGELALVTNK(gl)PR_
PRKAR2B Phosphorylation T69 -0.367 _TWGDLGAAAGGGT(ph)PSK_
PRKAR2B Phosphorylation S114 0.366 0.525 _RAS(ph)VCAEAYNPDEEEDDAESR_
PRKAR2B Ubiquitylation K359 0.640 _GQYFGELALVTNK(gl)PR_
PRKCA Phosphorylation S10 -0.650 0.036 _(ac)ADVFPGNDS(ph)TASQDVANR_
PRKCA Phosphorylation S13 -1.038 0.335 _(ac)ADVFPGNDSTAS(ph)QDVANR_
PRKCA Phosphorylation S226 0.693 0.415 _STLNPQWNES(ph)FTFK_
PRKCA Ubiquitylation K316 -0.522 -0.535 _LGPAGNK(gl)VISPSEDR_
PRKCD Ubiquitylation K138 -0.141 _SEDEAK(gl)FPTMNR_
PRKCD Ubiquitylation K222 0.185 0.658 _DTIFQK(gl)ER_
PRKCD Phosphorylation S302 -0.240 -0.222 _S(ph)DSASSEPVGIYQGFEK_
PRKCD Phosphorylation S304 0.378 0.289 _RSDS(ph)ASSEPVGIYQGFEK_
PRKCD Phosphorylation S506 -0.213 0.200 _AS(ph)TFCGTPDYIAPEILQGLK_
PRKCD Phosphorylation T507 -0.149 0.240 _AS(ph)TFCGTPDYIAPEILQGLK_
PRKCD Ubiquitylation K641 -2.000 _DYSNFDQEFLNEK(gl)AR_
PRKCD Phosphorylation S645 0.577 0.832 _ARLS(ph)YSDK_
PRKCD Phosphorylation S647 0.886 0.853 _ARLSYS(ph)DK_
RAF1 Phosphorylation S29 0.028 -0.571 _DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1 Phosphorylation T31 0.028 -0.669 _DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1 Phosphorylation S244 0.053 _YSTPHAFTFNTSS(ph)PSSEGSLSQR_
RAF1 Phosphorylation S259 -0.069 0.054 _STS(ph)TPNVHM(ox)VSTTLPVDSR_
RAF1 Phosphorylation S301 -0.651 _SHSESASPSALSSSPNNLS(ph)PTGWSQPK_
RAF1 Phosphorylation T303 -0.664 _SHSESASPSALSSSPNNLSPT(ph)GWSQPK_
RAF1 Phosphorylation S497 -0.449 _SRWS(ph)GSQQVEQPTGSVLWMAPEVIR_
RAF1 Phosphorylation S621 0.212 0.271 _SAS(ph)EPSLHR_
RAF1 Phosphorylation S642 -0.197 0.463 _AAHTEDINACTLTTS(ph)PR_
RICTOR Phosphorylation S21 -0.279 0.249 _NDS(ph)GEENVPLDLTR_
RICTOR Ubiquitylation K830 -0.874 _GYVAKQLEK(gl)_
RICTOR Phosphorylation S1284 2.625 _SNS(ph)VSLVPPGSSHTLPR_
RICTOR Phosphorylation S1302 -0.560 0.260 _RAQS(ph)LKAPSIATIK_
RICTOR Phosphorylation S1388 0.507 _ALSYAS(ph)LDKEDLLSPINQNTLQR_
RPS27A Ubiquitylation K6 1.066 0.995 _MQIFVK(gl)TLTGK_
RPS27A Ubiquitylation K11 -0.488 -0.081 _TLTGK(gl)TITLEVEPSDTIENVKAK(gl)_
RPS27A Ubiquitylation K27 -0.882 -0.159 _TLTGK(gl)TITLEVEPSDTIENVK(gl)AK_
RPS27A Ubiquitylation K29 -1.087 -1.029 _AK(gl)IQDK(gl)EGIPPDQQR_
RPS27A Ubiquitylation K33 -0.736 -0.407 _IQDK(gl)EGIPPDQQR_
RPS27A Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
RPS27A Phosphorylation S57 1.909 0.548 _TLS(ph)DYNIQK_
RPS27A Ubiquitylation K63 0.276 0.299 _TLSDYNIQK(gl)ESTLHLVLR_
RPS27A Ubiquitylation K99 0.109 2.111 _VK(gl)LAVLK_
RPS27A Ubiquitylation K104 0.674 2.102 _LAVLK(gl)YYK_
RPS27A Ubiquitylation K107 2.949 3.611 _YYK(gl)VDENGK(gl)ISR_
RPS27A Ubiquitylation K113 1.572 3.672 _YYK(gl)VDENGK(gl)ISR_
RPS27A Ubiquitylation K152 4.747 4.970 _CCLTYCFNK(gl)PEDK_
RPS27A Ubiquitylation K156 4.809 _CCLTYCFNKPEDK(gl)_
RPS6KB2 Ubiquitylation K99 -0.316 _VLGK(gl)GGYGK_
SH3GL2 Ubiquitylation K7 -0.268 _(ac)SVAGLK(gl)K_
SH3GL2 Ubiquitylation K8 -0.654 _(ac)SVAGLKK(gl)_
SH3GL2 Ubiquitylation K177 -0.477 0.450 _QGK(gl)IPDEELR_
SH3KBP1 Phosphorylation S230 0.300 0.186 _S(ph)IEVENDFLPVEK_
SOS1 Phosphorylation S1082 0.278 _IPESETESTASAPNS(ph)PR_
SOS1 Phosphorylation S1166 0.097 -0.094 _RPESAPAES(ph)SPSK_
SRC Phosphorylation S17 -0.604 -0.689 _S(ph)LEPAENVHGAGGGAFPASQTPSKPASADGHR_
SRC Phosphorylation S75 0.060 0.331 _LFGGFNSSDTVTS(ph)PQR_
STAM2 Ubiquitylation K182 -0.024 -0.067 _AIELSLQEQK(gl)QQHTETK_
STAM2 Ubiquitylation K189 -0.345 -0.068 _QQHTETK(gl)SLYPSSEIQLNNK_
STAM2 Ubiquitylation K202 -0.516 -0.231 _SLYPSSEIQLNNK(gl)VAR_
TSC2 Ubiquitylation K3 -1.397 _(ac)AK(gl)PTSKDSGLK_
TSC2 Ubiquitylation K14 -1.297 _DSGLKEK(gl)FK_
TSC2 Ubiquitylation K69 0.051 _MIGQICEVAK(gl)TK_
TSC2 Ubiquitylation K71 -0.157 _MIGQICEVAKTK(gl)_
TSC2 Ubiquitylation K258 -0.278 _ELCEPCWK(gl)LMR_
TSC2 Ubiquitylation K634 1.610 _LGLPNK(gl)DGVVR_
TSC2 Phosphorylation S950 -0.152 -0.529 _STS(ph)LNERPK_
TSC2 Phosphorylation S1064 -0.927 _SLLGLDSGELQSGPESSSS(ph)PGVHVR_
TSC2 Phosphorylation S1248 -0.604 _SNTDSAVVMEEGS(ph)PGEVPVLVEPPGLEDVEAALGMDRR_
TSC2 Phosphorylation S1329 -0.120 _S(ph)SSSPELQTLQDILGDPGDK_
TSC2 Phosphorylation S1331 -0.262 _SSS(ph)SPELQTLQDILGDPGDKADVGR_
TSC2 Phosphorylation S1332 -0.063 _SSSS(ph)PELQTLQDILGDPGDK_
TSC2 Phosphorylation S1355 0.174 0.351 _ADVGRLS(ph)PEVK_
TSC2 Phosphorylation S1362 0.859 _S(ph)QSGTLDGESAAWSASGEDSR_
TSC2 Phosphorylation S1364 0.522 0.550 _SQS(ph)GTLDGESAAWSASGEDSR_
TSC2 Phosphorylation T1366 0.137 _SQSGT(ph)LDGESAAWSASGEDSR_
TSC2 Phosphorylation S1396 0.498 _S(ph)PSGLRPR_
TSC2 Phosphorylation S1743 0.596 _RLISS(ph)VEDFTEFV_
UBA52 Ubiquitylation K6 1.066 0.995 _MQIFVK(gl)TLTGK_
UBA52 Ubiquitylation K11 -0.488 -0.081 _TLTGK(gl)TITLEVEPSDTIENVKAK(gl)_
UBA52 Ubiquitylation K27 -0.882 -0.159 _TLTGK(gl)TITLEVEPSDTIENVK(gl)AK_
UBA52 Ubiquitylation K29 -1.087 -1.029 _AK(gl)IQDK(gl)EGIPPDQQR_
UBA52 Ubiquitylation K33 -0.736 -0.407 _IQDK(gl)EGIPPDQQR_
UBA52 Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBA52 Phosphorylation S57 1.909 0.548 _TLS(ph)DYNIQK_
UBA52 Ubiquitylation K63 0.276 0.299 _TLSDYNIQK(gl)ESTLHLVLR_
UBA52 Ubiquitylation K93 0.181 2.418 _YNCDK(gl)MICR_
UBA52 Ubiquitylation K99 0.109 2.111 _VK(gl)LAVLK_
UBA52 Ubiquitylation K104 0.674 2.102 _LAVLK(gl)YYK_
UBA52 Ubiquitylation K107 2.949 3.611 _YYK(gl)VDENGK(gl)ISR_
UBA52 Ubiquitylation K113 1.572 3.672 _YYK(gl)VDENGK(gl)ISR_
UBA52 Ubiquitylation K152 4.747 4.970 _CCLTYCFNK(gl)PEDK_
UBA52 Ubiquitylation K156 4.809 _CCLTYCFNKPEDK(gl)_
YWHAB Ubiquitylation K11 1.057 1.322 _(ac)TMDKSELVQK(gl)AK_
YWHAB Ubiquitylation K13 0.060 0.388 _AK(gl)LAEQAER_
YWHAB Ubiquitylation K70 0.558 -0.175 _VISSIEQK(gl)TER_
YWHAB Ubiquitylation K140 0.531 _YLSEVASGDNK(gl)QTTVSNSQQAYQEAFEISKK_
YWHAB Ubiquitylation K159 0.300 _QTTVSNSQQAYQEAFEISK(gl)K_
YWHAB Ubiquitylation K160 -0.439 -0.371 _K(gl)EMQPTHPIR_


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