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Query: AKT1S1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AKT1S1 0 1.079 -0.070 -0.260

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AKT1S1 Phosphorylation T246 0.502 0.358 _LNT(ph)SDFQK_
AKT1S1 Phosphorylation S183 -0.539 -0.207 _S(ph)LPVSVPVWGFK_
AKT1S1 Phosphorylation S203 -0.783 -0.726 _SS(ph)DEENGPPSS(ph)PDLDR_
AKT1S1 Phosphorylation S211 -0.801 -1.311 _SS(ph)DEENGPPS(ph)SPDLDR_
AKT1S1 Phosphorylation S212 0.721 -1.311 _SS(ph)DEENGPPSS(ph)PDLDR_
AKT1S1 Phosphorylation S88 -2.758 -2.516 _AATAARPPAPPPAPQPPS(ph)PTPS(ph)PPRPTLAR_
AKT1S1 Phosphorylation S92 -3.077 -3.065 _AATAARPPAPPPAPQPPS(ph)PTPS(ph)PPRPTLAR_
AKT1S1 Phosphorylation T97 -3.450 _AATAARPPAPPPAPQPPS(ph)PTPSPPRPT(ph)LAR_

Background Information for AKT1S1:


Pubmed-AKT1S1 »
Uniprot-AKT1S1 »
Biogrid-AKT1S1 »
ProteomicsDB-AKT1S1 »

Tumorportal-AKT1S1 »
COSMIC-AKT1S1 »
GenomeRNAi-AKT1S1 »
Genecards-AKT1S1


Protein-protein Interactions for AKT1S1
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in AKT1S1
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring AKT1S1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring AKT1S1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0043234 protein complex Database 2.73
Category members Pathway Pathway_259 REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE 0 2.34
Category members Pathway Pathway_221 REACTOME_SIGNALLING_BY_NGF 0 2.14
Category members Pathway Pathway_660 REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR 0 2.12
Category members Pathway Pathway_724 PID_MTOR_4PATHWAY 0 2
Category members Pathway Pathway_706 REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR 0 1.96
Category members Pathway Pathway_258 REACTOME_SIGNALING_BY_EGFR_IN_CANCER 0 1.81
Category members Pathway Pathway_265 REACTOME_SIGNALING_BY_FGFR_IN_DISEASE 0 1.42
Category members Pathway Pathway_549 REACTOME_GAB1_SIGNALOSOME 0 1.25
Category members GO Category GO:0048015 phosphatidylinositol-mediated signaling Database 0.98
Category members Pathway Pathway_507 PID_MET_PATHWAY 0 0.82
Category members Pathway Pathway_229 REACTOME_SIGNALING_BY_ERBB2 0 0.68
Category members GO Category GO:0048011 neurotrophin TRK receptor signaling pathway Database 0.63
Category members Pathway Pathway_708 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING 0 0.61
Category members Pathway Pathway_254 REACTOME_SIGNALING_BY_FGFR 0 0.61
Category members Pathway Pathway_1142 PID_LKB1_PATHWAY 0 0.6
Category members Pathway Pathway_991 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL 0 0.6
Category members Pathway Pathway_599 REACTOME_SIGNALING_BY_SCF_KIT 0 0.48
Category members Pathway Pathway_255 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION 0 0.42
Category members Pathway Pathway_247 REACTOME_SIGNALING_BY_PDGF 0 0.4
Category members Pathway Pathway_590 REACTOME_PI_3K_CASCADE 0 0.37
Category members Pathway Pathway_607 REACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING 0 0.37
Category members GO Category GO:0038095 Fc-epsilon receptor signaling pathway Database 0.36
Category members Pathway Pathway_214 REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR 0 0.33
Category members GO Category GO:0032007 negative regulation of TOR signaling Database 0.33
Category members Pathway Pathway_604 REACTOME_PI3K_AKT_ACTIVATION 0 0.32
Category members Pathway Pathway_614 REACTOME_PI3K_EVENTS_IN_ERBB4_SIGNALING 0 0.32
Category members GO Category GO:0008543 fibroblast growth factor receptor signaling pathway Database 0.29
Category members GO Category GO:0045792 negative regulation of cell size Database 0.29
Category members GO Category GO:0007173 epidermal growth factor receptor signaling pathway Database 0.26
Category members Pathway Pathway_545 REACTOME_SIGNALING_BY_ERBB4 0 0.05
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members GO Category GO:0006469 negative regulation of protein kinase activity Database 0
Category members GO Category GO:0031931 TORC1 complex Database 0
Category members GO Category GO:0043523 regulation of neuron apoptotic process Database 0


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