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Query: RICTOR

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RICTOR 1 2.721 -0.330 0.710
RICTOR 1 2.721 -0.270 0.570

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RICTOR Phosphorylation S1302 -0.560 0.260 _RAQS(ph)LKAPSIATIK_
RICTOR Phosphorylation S21 -0.279 0.249 _NDS(ph)GEENVPLDLTR_
RICTOR Ubiquitylation K830 -0.874 _GYVAKQLEK(gl)_
RICTOR Phosphorylation S1284 2.625 _SNS(ph)VSLVPPGSSHTLPR_
RICTOR Phosphorylation S1388 0.507 _ALSYAS(ph)LDKEDLLSPINQNTLQR_

Background Information for RICTOR:


Pubmed-RICTOR »
Uniprot-RICTOR »
Biogrid-RICTOR »
ProteomicsDB-RICTOR »

Tumorportal-RICTOR »
COSMIC-RICTOR »
GenomeRNAi-RICTOR »
Genecards-RICTOR


Protein-protein Interactions for RICTOR
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait IMMT Cat. description Hein, Mann, Cell 2015
Category members IP bait KAT8 Cat. description Hein, Mann, Cell 2015
Category members IP bait LGALS3BP Cat. description Hein, Mann, Cell 2015
Category members IP bait MKNK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBG1 Cat. description Hein, Mann, Cell 2015
Category members IP bait AARSD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ANTXR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ASB3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AVIL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C6orf141 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDC16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CRYBA4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL13RA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL17RA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAPK14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MLST8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCAPH2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NXF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait P4HA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PROZ Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAPGEF5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SDF4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SKP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TKTL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSHB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSPYL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBGCP5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RICTOR
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26


Protein complexes (CORUM database) featuring RICTOR
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3979 mTORC2 complex (mTOR/FRAP1, LST8, mAVO3/RICTOR, SIN1) Database 0.04
Category members Corum 1893 mTOR-RICTOR complex Database 0
Category members Corum 2969 mTORC2 complex (mTOR/FRAP1, LST8, mAVO3/RICTOR) Database 0


Categories featuring RICTOR
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005488 binding Database 9.32
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_934 PID_PI3KCI_AKT_PATHWAY 0 2.5
Category members Pathway Pathway_259 REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE 0 2.34
Category members Pathway Pathway_221 REACTOME_SIGNALLING_BY_NGF 0 2.14
Category members Pathway Pathway_660 REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR 0 2.12
Category members Pathway Pathway_724 PID_MTOR_4PATHWAY 0 2
Category members Pathway Pathway_579 PID_ERBB1_DOWNSTREAM_PATHWAY 0 1.97
Category members Pathway Pathway_706 REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR 0 1.96
Category members Pathway Pathway_258 REACTOME_SIGNALING_BY_EGFR_IN_CANCER 0 1.81
Category members Pathway Pathway_924 PID_ILK_PATHWAY 0 1.75
Category members Pathway Pathway_265 REACTOME_SIGNALING_BY_FGFR_IN_DISEASE 0 1.42
Category members Pathway Pathway_645 PID_CXCR4_PATHWAY 0 1.42
Category members Pathway Pathway_549 REACTOME_GAB1_SIGNALOSOME 0 1.25
Category members GO Category GO:0048015 phosphatidylinositol-mediated signaling Database 0.98
Category members Pathway Pathway_229 REACTOME_SIGNALING_BY_ERBB2 0 0.68
Category members GO Category GO:0048011 neurotrophin TRK receptor signaling pathway Database 0.63
Category members GO Category GO:0051896 regulation of protein kinase B signaling Database 0.62
Category members Pathway Pathway_708 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING 0 0.61
Category members GO Category GO:0030334 regulation of cell migration Database 0.61
Category members Pathway Pathway_254 REACTOME_SIGNALING_BY_FGFR 0 0.61
Category members Pathway Pathway_599 REACTOME_SIGNALING_BY_SCF_KIT 0 0.48
Category members Pathway Pathway_255 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION 0 0.42
Category members Pathway Pathway_247 REACTOME_SIGNALING_BY_PDGF 0 0.4
Category members Pathway Pathway_590 REACTOME_PI_3K_CASCADE 0 0.37
Category members Pathway Pathway_607 REACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING 0 0.37
Category members GO Category GO:0038095 Fc-epsilon receptor signaling pathway Database 0.36
Category members GO Category GO:0032956 regulation of actin cytoskeleton organization Database 0.33
Category members Pathway Pathway_214 REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR 0 0.33
Category members GO Category GO:0043022 ribosome binding Database 0.33
Category members Pathway Pathway_604 REACTOME_PI3K_AKT_ACTIVATION 0 0.32
Category members Pathway Pathway_614 REACTOME_PI3K_EVENTS_IN_ERBB4_SIGNALING 0 0.32
Category members GO Category GO:0031532 actin cytoskeleton reorganization Database 0.29
Category members GO Category GO:0008543 fibroblast growth factor receptor signaling pathway Database 0.29
Category members GO Category GO:0007173 epidermal growth factor receptor signaling pathway Database 0.26
Category members GO Category GO:0030838 positive regulation of actin filament polymerization Database 0.21
Category members Pathway Pathway_622 REACTOME_CD28_CO_STIMULATION 0 0.13
Category members GO Category GO:0032314 regulation of Rac GTPase activity Database 0.11
Category members Pathway Pathway_620 REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY 0 0.06
Category members Pathway Pathway_545 REACTOME_SIGNALING_BY_ERBB4 0 0.05
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members Pathway Pathway_551 REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING 0 0
Category members Pathway Pathway_554 KEGG_MTOR_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_655 PID_CXCR3_PATHWAY 0 0
Category members GO Category GO:0001938 positive regulation of endothelial cell proliferation Database 0
Category members GO Category GO:0009790 embryo development Database 0
Category members GO Category GO:0031295 T cell costimulation Database 0
Category members GO Category GO:0031929 TOR signaling Database 0
Category members GO Category GO:0031932 TORC2 complex Database 0
Category members GO Category GO:0032008 positive regulation of TOR signaling Database 0
Category members GO Category GO:0042325 regulation of phosphorylation Database 0
Category members GO Category GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation Database 0
Category members GO Category GO:0051897 positive regulation of protein kinase B signaling Database 0


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