RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
W

Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
MAPK14	2	-0.160	-0.350
GNAI3	1	0.750	-0.890
GNAI3	1	0.750	-0.890	0.217			-0.334	-0.374
GNAO1	1	1.200	-1.320
GNAO1	1	1.200	-1.320	0.217			-0.334	-0.374
PIK3R2	1	2.740	-1.180				0.269	0.348
DNM1	1	-0.280	0.150		1.049	-1.435	1.593	1.013
RAF1	1	2.020	-1.230
KRAS	1	-0.510	0.620				1.031	0.887
KRAS	1	-0.510	0.620				0.246	-0.346
RICTOR	1	-0.330	0.710
RICTOR	1	-0.270	0.570
MAP2K1	1	-1.590	2.780
NRAS	1	1.810	-0.720				0.246	-0.346
MAP2K3	0	0.780	-0.600
PIK3CB	0	-1.390	2.350
PIK3CB	0	-0.710	1.450
GNAI1	0	-0.580	0.990
GNAI2	0	0.190	-0.520
GNAL	0	1.660	-1.170
GNAS	0	0.840	-0.750
GNAT1	0	-0.110	-0.270
GNAT2	0	0.140	-0.880
GNAT3	0	1.110	-0.500
GNB1	0	-0.700	0.650	0.713			0.504	0.538
GNB3	0	-1.020	1.280	0.713			0.504	0.538
MAPK3	0
MAP2K6	0	1.270	-0.780
PIK3R3	0	-0.140	-0.480
PIK3R3	0	-0.140	-0.480				-0.441	0.147
MAPKAP1	0	-0.450	1.350
PIK3CA	0
MAP2K2	0	-0.610	0.080
MAP2K2	0	-0.610	0.080
GNAI1	0	-0.580	0.990	0.116			-0.747
GNAZ	0	-0.020	-0.560
ARRB1	0	0.960	-0.620
PDPK1	0	0.050	-0.440
AKT1	0	-0.050	0.700
AKT1	0	0.860	-0.040
PIK3R1	0	1.910	-1.220				-0.441	0.147
MLST8	0	-0.170	0.220
HRAS	0	1.470	-0.520
SRC	0	0.050	0.470	-0.031
MTOR	0	-0.680	0.150	0.757			0.074	0.101

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
AKT1	Phosphorylation	S124	0.252	0.311	_SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1	Phosphorylation	S126	-0.241		_SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1	Ubiquitylation	K301	0.988		_EGIK(gl)DGATMK_
ARRB1	Phosphorylation	S412	0.138	0.253	_GMKDDKEEEEDGTGS(ph)PQLNNR_
DNM1	Ubiquitylation	K393	0.542		_EISYAIK(gl)NIHGVR_
DNM1	Phosphorylation	S764	-2.106	-1.205	_EALNIIGDISTSTVSTPVPPPVDDTWLQSASSHS(ph)PTPQR_
GNAI1	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAI1	Ubiquitylation	K92	0.873	0.567	_LK(gl)IDFGDSAR_
GNAI2	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAI3	Ubiquitylation	K29	0.529	-0.094	_NLREDGEK(gl)AAK_
GNAI3	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAI3	Ubiquitylation	K92	1.569		_LK(gl)IDFGEAAR_
GNAI3	Ubiquitylation	K349	-0.221	-0.339	_NNLK(gl)ECGLY_
GNAL	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAO1	Ubiquitylation	K29	0.529	-0.094	_NLREDGEK(gl)AAK_
GNAO1	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAO1	Ubiquitylation	K92	1.569		_LK(gl)IDFGEAAR_
GNAO1	Ubiquitylation	K349	-0.221	-0.339	_NNLK(gl)ECGLY_
GNAS	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAT1	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAT2	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAT3	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAZ	Ubiquitylation	K51	0.481	-0.051	_STIVK(gl)QMK_
GNAZ	Ubiquitylation	K189	0.945		_DMTTGIVENK(gl)FTFK_
GNB1	Ubiquitylation	K23	-0.282		_K(gl)ACADATLSQITNNIDPVGR_
GNB1	Ubiquitylation	K209	-0.296	-0.249	_LFVSGACDASAK(gl)LWDVR_
GNB3	Ubiquitylation	K23	-0.282		_K(gl)ACADATLSQITNNIDPVGR_
GNB3	Ubiquitylation	K209	-0.296	-0.249	_LFVSGACDASAK(gl)LWDVR_
HRAS	Ubiquitylation	K170	-1.005		_K(gl)LNPPDESGPGCMSCK_
KRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
KRAS	Ubiquitylation	K235	0.591	0.087	_TVDTK(gl)QAQDLAR_
KRAS	Ubiquitylation	K254	-0.450	-0.156	_SYGIPFIETSAK(gl)TR_
MAP2K1	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K1	Phosphorylation	S385		0.066	_RSDAEEVDFAGWLCSTIGLNQPS(ph)TPTHAAGV_
MAP2K1	Phosphorylation	T386		0.377	_RSDAEEVDFAGWLCSTIGLNQPST(ph)PTHAAGV_
MAP2K2	Phosphorylation	S23	0.873	0.258	_RKPVLPALTINPTIAEGPS(ph)PTSEGASEANLVDLQK_
MAP2K2	Phosphorylation	T25		0.439	_RKPVLPALTINPTIAEGPSPT(ph)SEGASEANLVDLQK_
MAP2K2	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K2	Phosphorylation	S293		-0.361	_ELEAIFGRPVVDGEEGEPHS(ph)ISPR_
MAP2K2	Phosphorylation	S295	-0.234	0.026	_ELEAIFGRPVVDGEEGEPHSIS(ph)PR_
MAP2K2	Phosphorylation	T394	0.570	0.158	_LNQPGT(ph)PTR_
MAP2K3	Ubiquitylation	K84	0.045	-0.277	_GAYGVVEK(gl)VR_
MAP2K3	Ubiquitylation	K232		-1.394	_TMDAGCK(gl)PYMAPER_
MAP2K3	Ubiquitylation	K247	0.065	-0.737	_INPELNQK(gl)GYNVK_
MAP2K6	Phosphorylation	T28	-1.813	-0.792	_EAFEQPQTSST(ph)PPRDLDSK_
MAP2K6	Ubiquitylation	K232		0.220	_INPELNQK(gl)GYSVK_
MAPK14	Phosphorylation	S2	3.221	3.623	_(ac)S(ph)QERPTFYR_
MAPK14	Phosphorylation	T180	0.958	1.087	_HTDDEM(ox)T(ph)GYVATR_
MAPK14	Phosphorylation	Y182	1.388	1.374	_HTDDEM(ox)TGY(ph)VATR_
MAPK14	Ubiquitylation	K249	0.073	-1.380	_LVGTPGAELLKK(gl)_
MAPK3	Phosphorylation	Y204	-0.807	-2.487	_IADPEHDHTGFLTEY(ph)VATR_
MAPK3	Ubiquitylation	K289		-0.608	_NYLQSLPSKTK(gl)_
MAPKAP1	Phosphorylation	T509		1.075	_RT(ph)SFSFQK_
MAPKAP1	Phosphorylation	S510	1.045	1.169	_RTS(ph)FSFQK_
MLST8	Phosphorylation	T3		-0.481	_(ac)MNT(ph)SPGTVGSDPVILATAGYDHTVR_
MLST8	Ubiquitylation	K245	-0.114	0.462	_FSPDSTLLATCSADQTCK(gl)IWR_
MTOR	Ubiquitylation	K309	-0.762	0.065	_DLMGFGTK(gl)PR_
MTOR	Ubiquitylation	K1257	-1.167	-0.901	_SGQGDALASGPVETGPMKK(gl)_
MTOR	Ubiquitylation	K1395		-1.255	_AYAK(gl)ALHYK_
MTOR	Ubiquitylation	K2066		-1.004	_GPQTLK(gl)ETSFNQAYGR_
MTOR	Ubiquitylation	K2166		-1.304	_IQSIAPSLQVITSK(gl)QRPR_
MTOR	Phosphorylation	T2471		0.329	_KT(ph)GTTVPESIHSFIGDGLVKPEALNK_
NRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
PDPK1	Phosphorylation	S241	0.358	0.361	_ANS(ph)FVGTAQYVSPELLTEK_
PDPK1	Ubiquitylation	K257	0.571	-0.234	_ANSFVGTAQYVSPELLTEK(gl)SACK_
PIK3CA	Ubiquitylation	K864	0.390	0.588	_NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA	Ubiquitylation	K868	0.204	0.651	_NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA	Ubiquitylation	K974	-0.273		_GAQECTK(gl)TREFER_
PIK3CB	Ubiquitylation	K1044		0.990	_SEEEALKQFKQK(gl)_
PIK3R2	Phosphorylation	S262		-2.237	_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2	Phosphorylation	S263		-2.237	_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2	Ubiquitylation	K500	-0.189		_IFEEQGQTQEK(gl)CSK_
PIK3R2	Ubiquitylation	K541	-0.609		_TK(gl)LEQQLR_
PIK3R2	Ubiquitylation	K564	-0.431	-1.022	_MNSLK(gl)PDLMQLR_
PIK3R3	Ubiquitylation	K226		-0.376	_YQQDQLVKEDNIDAVGKK(gl)_
PIK3R3	Ubiquitylation	K320		0.385	_LGEIHDSK(gl)MR_
RAF1	Phosphorylation	S29	0.028	-0.571	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	T31	0.028	-0.669	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	S244		0.053	_YSTPHAFTFNTSS(ph)PSSEGSLSQR_
RAF1	Phosphorylation	S259	-0.069	0.054	_STS(ph)TPNVHM(ox)VSTTLPVDSR_
RAF1	Phosphorylation	S301		-0.651	_SHSESASPSALSSSPNNLS(ph)PTGWSQPK_
RAF1	Phosphorylation	T303		-0.664	_SHSESASPSALSSSPNNLSPT(ph)GWSQPK_
RAF1	Phosphorylation	S497		-0.449	_SRWS(ph)GSQQVEQPTGSVLWMAPEVIR_
RAF1	Phosphorylation	S621	0.212	0.271	_SAS(ph)EPSLHR_
RAF1	Phosphorylation	S642	-0.197	0.463	_AAHTEDINACTLTTS(ph)PR_
RICTOR	Phosphorylation	S21	-0.279	0.249	_NDS(ph)GEENVPLDLTR_
RICTOR	Ubiquitylation	K830	-0.874		_GYVAKQLEK(gl)_
RICTOR	Phosphorylation	S1284	2.625		_SNS(ph)VSLVPPGSSHTLPR_
RICTOR	Phosphorylation	S1302	-0.560	0.260	_RAQS(ph)LKAPSIATIK_
RICTOR	Phosphorylation	S1388	0.507		_ALSYAS(ph)LDKEDLLSPINQNTLQR_
SRC	Phosphorylation	S17	-0.604	-0.689	_S(ph)LEPAENVHGAGGGAFPASQTPSKPASADGHR_
SRC	Phosphorylation	S75	0.060	0.331	_LFGGFNSSDTVTS(ph)PQR_