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Query: STAM2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
STAM2 0 0.559 -0.510 0.650

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
STAM2 Ubiquitylation K182 -0.024 -0.067 _AIELSLQEQK(gl)QQHTETK_
STAM2 Ubiquitylation K189 -0.345 -0.068 _QQHTETK(gl)SLYPSSEIQLNNK_
STAM2 Ubiquitylation K202 -0.516 -0.231 _SLYPSSEIQLNNK(gl)VAR_

Background Information for STAM2:


Pubmed-STAM2 »
Uniprot-STAM2 »
Biogrid-STAM2 »
ProteomicsDB-STAM2 »

Tumorportal-STAM2 »
COSMIC-STAM2 »
GenomeRNAi-STAM2 »
Genecards-STAM2


Protein-protein Interactions for STAM2
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in STAM2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ENTH_VHS IPR008942 0.96
Category members Ubiquitin-int_motif IPR003903 0.49
Category members SH3_2 IPR011511 0.08
Category members SH3_domain IPR001452 0
Category members VHS IPR002014 0
Category members VHS_subgr IPR018205 0


Protein complexes (CORUM database) featuring STAM2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3677 RIN1-STAM2-HRS complex Database 0
Category members Corum 3678 RIN1-STAM2-EGFR complex, EGF stimulated Database 0


Categories featuring STAM2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members Pathway Pathway_258 REACTOME_SIGNALING_BY_EGFR_IN_CANCER 0 1.81
Category members Pathway Pathway_666 KEGG_ENDOCYTOSIS 0 1.25
Category members Pathway Pathway_474 REACTOME_MEMBRANE_TRAFFICKING 0 1.14
Category members Pathway Pathway_809 REACTOME_EGFR_DOWNREGULATION 0 1.1
Category members GO Category GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway Database 0.64
Category members GO Category GO:0031901 early endosome membrane Database 0.58
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0016197 endosomal transport Database 0.43
Category members GO Category GO:0007173 epidermal growth factor receptor signaling pathway Database 0.26
Category members Pathway Pathway_447 KEGG_JAK_STAT_SIGNALING_PATHWAY 0 0.13
Category members Pathway Pathway_601 PID_IL2_1PATHWAY 0 0.1
Category members Pathway Pathway_800 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT 0 0.06


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