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Query: PAG1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PAG1 0 3.209 -0.550 1.760

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PAG1 Phosphorylation S288 0.574 0.875 _EGGEAEESATDTTS(ph)ETNK_

Background Information for PAG1:





Protein-protein Interactions for PAG1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACBD7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C1QL4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLPB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CSK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CYP2S1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DUSP22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FKBP11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GJB7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR141 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GSTK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HOXB5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MTUS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCSTN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NTRK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHGC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PMS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPS27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait S1PR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SERHL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC25A41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TIGD5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM185A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF517 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PAG1

Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring PAG1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PAG1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_258 REACTOME_SIGNALING_BY_EGFR_IN_CANCER 0 1.81
Category members Pathway Pathway_645 PID_CXCR4_PATHWAY 0 1.42
Category members Pathway Pathway_549 REACTOME_GAB1_SIGNALOSOME 0 1.25
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_561 PID_PDGFRB_PATHWAY 0 1.18
Category members GO Category GO:0007173 epidermal growth factor receptor signaling pathway Database 0.26
Category members Pathway Pathway_573 REACTOME_TCR_SIGNALING 0 0.2
Category members Pathway Pathway_705 PID_CD8_TCR_PATHWAY 0 0.17
Category members GO Category GO:0045121 membrane raft Database 0.11
Category members Pathway Pathway_687 PID_TCR_PATHWAY 0 0.08
Category members GO Category GO:0050852 T cell receptor signaling pathway Database 0.06
Category members Pathway Pathway_1234 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS 0 0
Category members Pathway Pathway_432 PID_SHP2_PATHWAY 0 0
Category members Pathway Pathway_540 PID_BCR_5PATHWAY 0 0
Category members GO Category GO:0005070 SH3/SH2 adaptor activity Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0
Category members GO Category GO:0042169 SH2 domain binding Database 0
Category members GO Category GO:0050863 regulation of T cell activation Database 0
Category members GO Category GO:0050868 negative regulation of T cell activation Database 0


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