RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
RIPK2	1	-1.740	3.580
PIK3R2	1	2.740	-1.180				0.269	0.348
PLCG1	1	-0.170	0.000
VASP	1	0.180	0.270				1.849
BCL10	1	0.000	0.200
ENAH	1	0.460	-0.080
ENAH	1	0.460	-0.080	0.413			0.435	0.673
PIK3CB	0	-1.390	2.350
PIK3CB	0	-0.710	1.450
TAB2	0	-0.030	-0.580
PRKCQ	0	0.410	0.020
PAG1	0	-0.550	1.760
CSK	0	1.200	-0.960	-1.211
CSK	0	1.200	-0.960
IKBKB	0	0.400	0.610
PIK3CA	0
TMEM189-UB	0
TMEM189-UB	0
MAP3K7	0	-1.120	1.140	-1.048
PDPK1	0	0.050	-0.440
PIK3R1	0	1.910	-1.220				-0.441	0.147
PAK1	0	1.190	-0.630
NCK1	0	-0.370	0.580
RELA	0	-1.130	1.600	0.793
PAK2	0	-0.760	1.040
LCK	0	-0.490	1.390				0.295	0.576
EVL	0	0.030	-0.430	0.413			0.435	0.673
EVL	0	0.030	-0.430
CHUK	0			-0.480

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
BCL10	Phosphorylation	S138	1.515	1.393	_SNS(ph)DESNFSEK_
CHUK	Ubiquitylation	K296		-1.637	_GGPVDLTLK(gl)QPR_
CSK	Ubiquitylation	K196	-0.133		_SGWALNMKELK(gl)_
ENAH	Phosphorylation	S405	1.519	-1.355	_VS(ph)RMEDTSFPSGGNAIGVNSASSK_
ENAH	Phosphorylation	S463	0.378	0.115	_GS(ph)TIETEQKEDKGEDSEPVTSK_
ENAH	Phosphorylation	T464	0.756	0.047	_GST(ph)IETEQKEDKGEDSEPVTSK_
ENAH	Ubiquitylation	K483	-1.901		_GSTIETEQKEDKGEDSEPVTSK(gl)ASSTSTPEPTR_
EVL	Phosphorylation	S246	-0.996	0.095	_VQRPEDASGGSS(ph)PSGTSK_
EVL	Phosphorylation	S329	0.147	0.356	_S(ph)NSVEKPVSSILSR_
EVL	Phosphorylation	S331	0.246	0.219	_SNS(ph)VEKPVSSILSR_
EVL	Phosphorylation	S349	0.089	1.311	_TPSVAKS(ph)PEAK_
EVL	Ubiquitylation	K483	-1.901		_GSTIETEQKEDKGEDSEPVTSK(gl)ASSTSTPEPTR_
IKBKB	Ubiquitylation	K106	0.253		_K(gl)YLNQFENCCGLR_
IKBKB	Phosphorylation	S672	0.670	0.244	_GPVSGS(ph)PDSMNASR_
LCK	Phosphorylation	T37		-0.435	_YRPENTPEPVSTSVSHYGAEPT(ph)TVSPCPSSSAK_
LCK	Ubiquitylation	K191	-0.112	0.264	_ESETTK(gl)GAYSLSIR_
LCK	Ubiquitylation	K235	0.323		_AQFDTLQK(gl)LVK_
LCK	Ubiquitylation	K259		-1.613	_LTTVCPTVK(gl)PQTQGLAK_
MAP3K7	Phosphorylation	S374	0.149	-0.337	_GS(ph)SVESLPPTSEGK_
MAP3K7	Phosphorylation	S375	0.171	-0.087	_GSS(ph)VESLPPTSEGK_
MAP3K7	Phosphorylation	S389	1.072	1.445	_RMS(ph)ADMSEIEAR_
MAP3K7	Phosphorylation	S439	0.246	0.198	_S(ph)IQDLTVTGTEPGQVSSR_
MAP3K7	Ubiquitylation	K474	-0.385	-0.242	_MITTSGPTSEK(gl)PTR_
MAP3K7	Ubiquitylation	K589	-0.104		_SLSTYYQQCK(gl)K_
MAP3K7	Ubiquitylation	K590	-0.551	0.560	_K(gl)QLEVIR_
NCK1	Phosphorylation	S85	-0.027	-0.877	_RKPS(ph)VPDSASPADDSFVDPGER_
NCK1	Phosphorylation	S91		0.493	_RKPSVPDSAS(ph)PADDSFVDPGER_
PAG1	Phosphorylation	S288	0.574	0.875	_EGGEAEESATDTTS(ph)ETNK_
PAK1	Phosphorylation	S174	-1.439	-0.597	_AVSETPAVPPVS(ph)EDEDDDDDDATPPPVIAPRPEHTK_
PAK1	Phosphorylation	T212		0.312	_SVIEPLPVT(ph)PTR_
PAK1	Phosphorylation	T219	-0.560	-0.962	_DVAT(ph)SPISPTENNTT(ph)PPDALTR_
PAK1	Phosphorylation	S220	-0.916	-0.774	_DVATS(ph)PISPTENNTTPPDALTR_
PAK1	Phosphorylation	S223	1.033	0.153	_DVATSPIS(ph)PTENNTTPPDALTR_
PAK1	Phosphorylation	T225	-1.278		_DVATSPISPT(ph)ENNTTPPDALTR_
PAK1	Phosphorylation	T230	-1.418	-1.502	_DVATSPISPTENNTT(ph)PPDALTR_
PAK2	Phosphorylation	S2	-1.228	-0.902	_(ac)S(ph)DNGELEDKPPAPPVR_
PAK2	Ubiquitylation	K136	1.213		_FYDSNTVK(gl)QK_
PAK2	Phosphorylation	S141	-0.294	-0.321	_YLS(ph)FTPPEK_
PAK2	Ubiquitylation	K370	-0.565		_DIK(gl)SDNVLLGMEGSVK_
PDPK1	Phosphorylation	S241	0.358	0.361	_ANS(ph)FVGTAQYVSPELLTEK_
PDPK1	Ubiquitylation	K257	0.571	-0.234	_ANSFVGTAQYVSPELLTEK(gl)SACK_
PIK3CA	Ubiquitylation	K864	0.390	0.588	_NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA	Ubiquitylation	K868	0.204	0.651	_NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA	Ubiquitylation	K974	-0.273		_GAQECTK(gl)TREFER_
PIK3CB	Ubiquitylation	K1044		0.990	_SEEEALKQFKQK(gl)_
PIK3R2	Phosphorylation	S262		-2.237	_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2	Phosphorylation	S263		-2.237	_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2	Ubiquitylation	K500	-0.189		_IFEEQGQTQEK(gl)CSK_
PIK3R2	Ubiquitylation	K541	-0.609		_TK(gl)LEQQLR_
PIK3R2	Ubiquitylation	K564	-0.431	-1.022	_MNSLK(gl)PDLMQLR_
PLCG1	Ubiquitylation	K300		8.031	_DLK(gl)NMLSQVNYR_
PLCG1	Ubiquitylation	K348		-0.219	_SLMYSAQK(gl)TMDLPFLEASTLR_
PLCG1	Ubiquitylation	K552		-0.355	_NMAQYFK(gl)K_
PLCG1	Ubiquitylation	K553		-0.355	_NMAQYFK(gl)K_
PLCG1	Ubiquitylation	K1063	0.864	0.355	_LTEGK(gl)IMER_
PLCG1	Phosphorylation	S1370	0.475	0.515	_AREGS(ph)FESR_
PRKCQ	Phosphorylation	S685		0.911	_ALINS(ph)MDQNMFR_
RIPK2	Ubiquitylation	K410	-2.810		_AAFCDHK(gl)TTPCSSAIINPLSTAGNSER_
RIPK2	Phosphorylation	S531	0.884	0.839	_SPS(ph)LNLLQNK_
RIPK2	Ubiquitylation	K538	-2.659		_SPSLNLLQNK(gl)SM_
TAB2	Phosphorylation	S580		-0.075	_S(ph)NSISQIPSLEEMQQLR_
TAB2	Phosphorylation	S582		0.331	_SNS(ph)ISQIPSLEEMQQLR_
TAB2	Ubiquitylation	K653	-0.519	-0.200	_SIIK(gl)TPK_
TMEM189-UBE2V1	Ubiquitylation	K42	-0.791	0.215	_ELAALYSPGK(gl)R_
TMEM189-UBE2V1	Ubiquitylation	K129	0.440	0.709	_LMMSK(gl)ENMK_
TMEM189-UBE2V1	Ubiquitylation	K291	-0.071	0.214	_IYSLK(gl)IECGPK_
VASP	Phosphorylation	S239	0.625	-0.774	_VS(ph)KQEEASGGPTAPK_