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Query: ENAH

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ENAH 1 1.365 0.460 -0.080
ENAH 1 1.365 0.460 -0.080 0.413 0.435 0.673

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ENAH Phosphorylation S506 0.226 _TNTM(ox)NGS(ph)KSPVISRPK_
ENAH Phosphorylation S463 0.378 0.115 _GS(ph)TIETEQKEDKGEDSEPVTSK_
ENAH Phosphorylation S508 -0.208 0.083 _S(ph)PVISRPK_
ENAH Phosphorylation T464 0.756 0.047 _GST(ph)IETEQKEDKGEDSEPVTSK_
ENAH Phosphorylation S405 1.519 -1.355 _VS(ph)RMEDTSFPSGGNAIGVNSASSK_
ENAH Ubiquitylation K483 -1.901 _GSTIETEQKEDKGEDSEPVTSK(gl)ASSTSTPEPTR_

Background Information for ENAH:


Pubmed-ENAH »
Uniprot-ENAH »
Biogrid-ENAH »
ProteomicsDB-ENAH »

Tumorportal-ENAH »
COSMIC-ENAH »
GenomeRNAi-ENAH »
Genecards-ENAH


Protein-protein Interactions for ENAH
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ABI1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PRPF4 Cat. description Hein, Mann, Cell 2015
Category members IP bait TACC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait BCHE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EVL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PARL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PFN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRMT6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PVRL4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMOD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VASP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZYX Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ENAH
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ran_bind_dom IPR000156 2.46
Category members VASP_tetra IPR014885 0.29
Category members WH1/EVH1 IPR000697 0


Protein complexes (CORUM database) featuring ENAH
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ENAH
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003779 actin binding Database 5.41
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0046907 intracellular transport Database 3.25
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_292 PID_ECADHERIN_NASCENT_AJ_PATHWAY 0 2.74
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members Pathway Pathway_466 PID_ECADHERIN_STABILIZATION_PATHWAY 0 1.4
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members Pathway Pathway_673 REACTOME_AXON_GUIDANCE 0 1.06
Category members Pathway Pathway_568 PID_CDC42_PATHWAY 0 0.68
Category members GO Category GO:0005925 focal adhesion Database 0.68
Category members GO Category GO:0008154 actin polymerization or depolymerization Database 0.47
Category members GO Category GO:0050699 WW domain binding Database 0.36
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members Pathway Pathway_701 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES 0 0.22
Category members Pathway Pathway_573 REACTOME_TCR_SIGNALING 0 0.2
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members Pathway Pathway_580 KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 0 0.08
Category members GO Category GO:0045202 synapse Database 0.06
Category members GO Category GO:0050852 T cell receptor signaling pathway Database 0.06
Category members GO Category GO:0030175 filopodium Database 0.05
Category members GO Category GO:0001725 stress fiber Database 0.04
Category members Pathway Pathway_1031 REACTOME_SIGNALING_BY_ROBO_RECEPTOR 0 0
Category members GO Category GO:0001843 neural tube closure Database 0
Category members GO Category GO:0017124 SH3 domain binding Database 0
Category members GO Category GO:0030054 cell junction Database 0


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