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Results for the Category
neural tube closure
(GO:0001843)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
SETD2 3 -1.690 2.960 1.619 1.725 -0.978 0.379
HECTD1 1 -0.730 0.420 0.181 -1.016 -0.692
TSC2 1 0.810 -0.710
TSC2 1 0.810 -0.710 -0.715
PFN1 1 -0.430 -0.180 0.002 2.497 -0.084 0.348 -0.059
ARID1A 1 0.360 -0.350 0.683 0.272 0.870 -0.131 0.043
VASP 1 0.180 0.270 1.849
BCL10 1 0.000 0.200
ENAH 1 0.460 -0.080
ENAH 1 0.460 -0.080 0.413 0.435 0.673
SKI 1 -1.870 2.800 -1.139 -0.588
SEMA4C 1 -1.890 3.770
DVL2 0 -0.050 0.580
ZIC2 0 0.440 -0.440
NCKAP1 0 1.120 -0.620 0.347 0.023 -0.306 1.181 0.448
LRP6 0 0.210 0.050
TEAD2 0 0.050 -0.130
CECR2 0 1.060 -0.940 -1.272 0.502 0.344
SALL4 0 0.590 0.130 -0.080 0.063 0.213 0.247 0.009
SALL1 0 -0.080 0.063 0.213 0.247 0.009
COBL 0 -1.440 1.820
SUFU 0 1.190 -0.990
PTK7 0 -0.240 0.340 -0.232 0.174
WNT5A 0
TWIST1 0 -0.640 1.150
ROCK2 0 -1.660 2.330
SHROOM3 0 1.220 -0.790 -3.936
BBS4 0 0.310 0.160
KDM6A 0 1.910 -0.840 -0.406 0.870
KDM6A 0 1.910 -0.840 -0.542 -0.153
ARHGAP35 0 1.030 -0.620 -0.833 0.397 0.020
VANGL2 0 -1.030 1.450
IFT122 0 0.590 -0.240
IFT122 0 1.590 -0.690
T 0 0.200 -0.340 -0.755
DLC1 0 -0.650 0.390
TSC1 0 1.100 -0.150
ZEB2 0 -0.420 1.170 0.364 0.973
GLMN 0 1.160 -1.250 0.000
DEAF1 0 1.330 -0.440 -1.070
ALX1 0 0.810 -0.890
MED12 0 -0.180 -0.500 -1.501 -0.491
PTCH1 0 0.630 -0.690
PLXNB2 0 1.170 -1.050 1.011 0.828
OPA1 0 -0.940 1.320 0.057 -0.292
OPA1 0 -0.940 1.320 0.962 0.828 0.737
PHACTR4 0 1.170 -1.060

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ALX1 Phosphorylation T68 0.678 0.289 _T(ph)SPCQDSSVNYGITK_
ALX1 Phosphorylation S69 0.678 0.484 _T(ph)SPCQDSSVNYGITK_
ARHGAP35 Phosphorylation S975 -0.388 -0.423 _AGS(ph)PLCNSNLQDSEEDIEPSYSLFR_
ARHGAP35 Phosphorylation S1072 -0.719 _SVS(ph)SSPWLPQDGFDPSDYAEPMDAVVKPR_
ARHGAP35 Phosphorylation S1150 1.218 0.094 _KVS(ph)IVSKPVLYR_
ARHGAP35 Phosphorylation S1179 0.400 0.591 _TSFSVGS(ph)DDELGPIR_
ARID1A Phosphorylation S363 0.211 0.022 _SHHAPM(ox)S(ph)PGSSGGGGQPLAR_
ARID1A Phosphorylation S367 -0.142 _SHHAPMSPGSS(ph)GGGGQPLAR_
ARID1A Phosphorylation S381 0.335 _TPQPS(ph)SPMDQMGK_
ARID1A Phosphorylation S382 1.506 0.780 _TPQPSS(ph)PMDQMGK_
ARID1A Phosphorylation S696 -0.934 -0.737 _GPS(ph)PSPVGSPASVAQSR_
ARID1A Phosphorylation S702 0.267 -0.175 _GPS(ph)PSPVGS(ph)PASVAQSR_
ARID1A Phosphorylation S705 0.157 _GPS(ph)PSPVGSPAS(ph)VAQSR_
ARID1A Phosphorylation S772 -0.112 -0.485 _NPQMPQYSSPQPGSALS(ph)PR_
ARID1A Phosphorylation S1182 1.584 1.063 _S(ph)NSVGIQDAFNDGSDSTFQK_
ARID1A Phosphorylation S1184 1.732 1.114 _SNS(ph)VGIQDAFNDGSDSTFQK_
ARID1A Phosphorylation S1754 0.131 -0.654 _VS(ph)SPAPM(ox)EGGEEEEELLGPK_
ARID1A Phosphorylation S1755 -0.409 -0.587 _VSS(ph)PAPMEGGEEEEELLGPK_
ARID1A Phosphorylation S1944 -0.489 _FPFGIS(ph)PAQSHR_
BBS4 Ubiquitylation K28 -0.615 _TQFPVSTESQK(gl)PR_
BBS4 Ubiquitylation K302 -2.331 _YVAAISCLK(gl)R_
BBS4 Ubiquitylation K408 -2.242 _NALAQYQEMEK(gl)K_
BBS4 Ubiquitylation K409 -2.242 _NALAQYQEMEK(gl)K_
BCL10 Phosphorylation S138 1.515 1.393 _SNS(ph)DESNFSEK_
COBL Phosphorylation S962 1.121 -0.189 _LS(ph)TQDRPAAIHR_
DEAF1 Phosphorylation S176 -1.583 -1.990 _GPAAPLTPGPQS(ph)PPTPLAPGQEK_
DLC1 Phosphorylation S842 -0.139 _TGS(ph)FHGPGHISLR_
DLC1 Phosphorylation S946 -0.497 _FSDEGDSDSALDSVSPCPSS(ph)PK_
DVL2 Ubiquitylation K343 0.846 -1.366 _DIVHK(gl)PGPIVLTVAK_
ENAH Phosphorylation S405 1.519 -1.355 _VS(ph)RMEDTSFPSGGNAIGVNSASSK_
ENAH Phosphorylation S463 0.378 0.115 _GS(ph)TIETEQKEDKGEDSEPVTSK_
ENAH Phosphorylation T464 0.756 0.047 _GST(ph)IETEQKEDKGEDSEPVTSK_
ENAH Ubiquitylation K483 -1.901 _GSTIETEQKEDKGEDSEPVTSK(gl)ASSTSTPEPTR_
GLMN Ubiquitylation K11 0.194 _(ac)AVEELQSIIK(gl)R_
GLMN Ubiquitylation K214 0.595 _FCFK(gl)SLK_
GLMN Ubiquitylation K433 0.331 _NQIDMSLK(gl)R_
GLMN Ubiquitylation K525 -0.081 _AHYEAEIK(gl)NSQEAQK_
HECTD1 Ubiquitylation K255 -0.575 -0.414 _MAAAGGTVSGPSSACK(gl)PGR_
HECTD1 Ubiquitylation K340 1.634 _KALPK(gl)SSAGSTGR_
HECTD1 Phosphorylation S631 -0.150 _VSTLAGPS(ph)SDDENEEESKPEKEDEPQEDAK_
HECTD1 Phosphorylation S632 -0.423 -0.150 _VSTLAGPSS(ph)DDENEEESKPEKEDEPQEDAK_
HECTD1 Ubiquitylation K1253 -0.263 _AAK(gl)EAEANLRR_
HECTD1 Ubiquitylation K1272 -0.167 _SQVLK(gl)YMVPGAR_
HECTD1 Ubiquitylation K1287 -0.787 -0.617 _GLDWK(gl)WR_
HECTD1 Ubiquitylation K1371 -0.621 _NNCPDK(gl)TSAAAGSSSR_
HECTD1 Ubiquitylation K1382 0.103 _K(gl)GSSSSVCSVASSSDISLGSTK_
HECTD1 Ubiquitylation K1768 -0.397 _TWDDDYVLK(gl)R_
HECTD1 Ubiquitylation K2471 -0.108 _DGFNK(gl)VFPMEK_
HECTD1 Ubiquitylation K2605 0.861 _LLAATMEK(gl)GFHLN_
IFT122 Ubiquitylation K804 -0.101 _MLITK(gl)QADWAR_
IFT122 Ubiquitylation K1084 -0.071 _FQK(gl)SIELGTLTIR_
KDM6A Phosphorylation S866 -0.439 _TDNS(ph)VASSPSSAISTATPS(ph)PK_
KDM6A Phosphorylation S870 0.867 -0.013 _TDNSVASS(ph)PSSAISTATPSPK_
KDM6A Phosphorylation S872 0.757 _TDNSVASSPS(ph)SAISTATPSPK_
KDM6A Phosphorylation S876 -0.001 _TDNSVAS(ph)SPSSAIS(ph)TATPSPK_
KDM6A Phosphorylation T879 -0.585 0.018 _TDNSVASS(ph)PSSAISTAT(ph)PSPK_
KDM6A Phosphorylation S881 -0.285 -0.548 _TDNSVASS(ph)PSSAISTATPS(ph)PK_
LRP6 Ubiquitylation K1443 -0.221 _GK(gl)SMISSLSIMGGSSGPPYDR_
MED12 Ubiquitylation K429 -0.439 _EIEQQIK(gl)ER_
MED12 Ubiquitylation K531 -0.272 _AMVVAKLLEK(gl)_
MED12 Phosphorylation S635 -1.278 -0.801 _GDLAFGAPGPRPPS(ph)PFDDPADDPEHK_
MED12 Ubiquitylation K1001 -1.092 _VK(gl)NTIYCNVEPSESNMR_
MED12 Ubiquitylation K1661 -1.781 _DVITCEPQGSLIDTK(gl)GNK_
MED12 Ubiquitylation K1682 -0.745 _EGLQVSTK(gl)QK_
MED12 Ubiquitylation K1684 -0.960 _EGLQVSTK(gl)QK_
NCKAP1 Ubiquitylation K12 -1.114 -0.228 _SVLQPSQQK(gl)LAEK_
NCKAP1 Ubiquitylation K16 0.326 _LAEK(gl)LTILNDR_
NCKAP1 Ubiquitylation K190 -0.009 _LGQMIVDYENPLK(gl)K_
NCKAP1 Ubiquitylation K191 -0.009 _LGQMIVDYENPLK(gl)K_
NCKAP1 Ubiquitylation K1075 -0.817 _IGQETDK(gl)TTTR_
OPA1 Ubiquitylation K261 0.390 _AAGQYSTSYAQQK(gl)R_
PFN1 Ubiquitylation K54 -0.190 0.319 _TFVNITPAEVGVLVGK(gl)DR_
PFN1 Ubiquitylation K70 0.186 0.451 _SSFYVNGLTLGGQK(gl)CSVIR_
PFN1 Ubiquitylation K91 -0.513 -0.205 _TK(gl)STGGAPTFNVTVTK_
PFN1 Ubiquitylation K105 0.309 -0.352 _STGGAPTFNVTVTK(gl)TDK_
PFN1 Ubiquitylation K108 0.414 -0.098 _TDK(gl)TLVLLMGK_
PFN1 Ubiquitylation K126 0.640 0.539 _EGVHGGLINK(gl)K_
PFN1 Ubiquitylation K127 0.582 0.353 _EGVHGGLINKK(gl)_
PHACTR4 Phosphorylation S118 0.238 0.418 _SSS(ph)PVQVEEEPVR_
PHACTR4 Phosphorylation S176 0.748 0.601 _RPLS(ph)SSHEASEGQAK_
PHACTR4 Phosphorylation S270 -1.012 _NS(ph)NPVIAELSQAINSGTLLSKPS(ph)PPLPPK_
PHACTR4 Phosphorylation S291 -0.803 _NSNPVIAELSQAINSGTLLSKPS(ph)PPLPPK_
PHACTR4 Phosphorylation S344 -2.017 -2.249 _SPS(ph)PPLPTHIPPEPPRT(ph)PPFPAK_
PHACTR4 Phosphorylation T358 -1.951 -2.796 _SPS(ph)PPLPTHIPPEPPRT(ph)PPFPAK_
PHACTR4 Phosphorylation S464 -0.157 0.013 _S(ph)LPITIEM(ox)LK_
PHACTR4 Phosphorylation S590 -0.597 -0.603 _RLS(ph)QRPTPEELEQR_
PHACTR4 Phosphorylation S628 0.269 0.069 _KLS(ph)QRPTVAELLAR_
PHACTR4 Phosphorylation T632 0.174 0.079 _LSQRPT(ph)VAELLAR_
PLXNB2 Ubiquitylation K76 0.452 _LQLEQQVATGPALDNK(gl)K_
PLXNB2 Ubiquitylation K77 0.452 _LQLEQQVATGPALDNK(gl)K_
PLXNB2 Ubiquitylation K747 0.202 _SYGK(gl)NIDSK_
PLXNB2 Ubiquitylation K1442 -0.119 _GPVDAVQK(gl)K_
PLXNB2 Ubiquitylation K1443 -0.119 _GPVDAVQK(gl)K_
PLXNB2 Ubiquitylation K1738 -0.751 _DSPSNK(gl)LLYAK_
PTCH1 Ubiquitylation K904 -0.390 _DKPIDISQLTK(gl)QR_
PTK7 Ubiquitylation K843 0.757 0.315 _SLQSK(gl)DEQQQLDFRR_
PTK7 Ubiquitylation K906 0.519 -0.411 _LK(gl)SQPLSTK_
ROCK2 Ubiquitylation K1222 -0.679 _ADAK(gl)EIPR_
SALL1 Phosphorylation S1119 -1.156 -1.235 _DTPTSHVPSGPLSSSATS(ph)PVLLPALPR_
SALL4 Phosphorylation S1119 -1.156 -1.235 _DTPTSHVPSGPLSSSATS(ph)PVLLPALPR_
SEMA4C Ubiquitylation K481 -1.114 _SLVLSQSK(gl)K_
SEMA4C Ubiquitylation K482 -1.114 _SLVLSQSK(gl)K_
SETD2 Phosphorylation S130 -0.443 _M(ox)EIGDTLSTAEES(ph)SPPK_
SETD2 Phosphorylation S131 -0.001 -0.163 _M(ox)EIGDTLSTAEESS(ph)PPK_
SETD2 Phosphorylation S624 0.374 0.432 _LNDS(ph)PTLKK_
SETD2 Phosphorylation S708 0.398 _TDAVLM(ox)TSDDSVTGSELS(ph)PLVK_
SETD2 Phosphorylation S742 -1.167 -1.779 _S(ph)ESPFRETEPLVSPHQDK_
SETD2 Phosphorylation S744 -0.557 _SES(ph)PFRETEPLVSPHQDK_
SETD2 Phosphorylation T1083 0.552 _NSTLPMEET(ph)SPCSSR_
SETD2 Phosphorylation S1084 -0.102 _NSTLPMEETS(ph)PCSSR_
SETD2 Phosphorylation T1872 -0.148 -1.034 _LSTEADTDT(ph)PKK_
SETD2 Phosphorylation S1885 0.110 _IIS(ph)ENSMDSAISDATSELEGK_
SETD2 Phosphorylation S1888 1.247 0.067 _IISENS(ph)M(ox)DSAISDATSELEGK_
SHROOM3 Phosphorylation S816 0.829 _TVS(ph)TSSTSGNDFEETK_
SHROOM3 Phosphorylation S910 -0.534 -1.354 _DRPGS(ph)PESPLLDAPFSR_
SHROOM3 Phosphorylation S1441 -0.680 -0.409 _EDS(ph)LPEESSAPDFANLK_
SKI Ubiquitylation K294 -0.126 -0.054 _AYILLSQDYTGK(gl)EEQAR_
SKI Ubiquitylation K365 -0.244 -0.390 _TLAGSSNK(gl)SLGCVHPR_
SKI Phosphorylation S431 -0.475 _VVS(ph)SPPCAAAVSR_
SKI Phosphorylation S432 -0.742 -0.438 _VVSS(ph)PPCAAAVSR_
SKI Phosphorylation S480 -1.160 -1.491 _LTVDTPGAPETLAPVAAPEEDKDS(ph)EAEVEVESR_
SUFU Ubiquitylation K303 -0.015 _RLSGK(gl)DTEQIR_
SUFU Ubiquitylation K321 -1.917 -1.398 _GLEINSK(gl)PVLPPINPQR_
SUFU Phosphorylation S346 0.344 0.498 _KDS(ph)LESDSSTAIIPHELIR_
TEAD2 Ubiquitylation K50 1.259 0.615 _IILSDEGK(gl)MYGR_
TEAD2 Ubiquitylation K262 -0.150 _VCSFGK(gl)QVVEK_
TSC1 Phosphorylation S505 0.141 0.350 _GGFDS(ph)PFYR_
TSC2 Ubiquitylation K3 -1.397 _(ac)AK(gl)PTSKDSGLK_
TSC2 Ubiquitylation K14 -1.297 _DSGLKEK(gl)FK_
TSC2 Ubiquitylation K69 0.051 _MIGQICEVAK(gl)TK_
TSC2 Ubiquitylation K71 -0.157 _MIGQICEVAKTK(gl)_
TSC2 Ubiquitylation K258 -0.278 _ELCEPCWK(gl)LMR_
TSC2 Ubiquitylation K634 1.610 _LGLPNK(gl)DGVVR_
TSC2 Phosphorylation S950 -0.152 -0.529 _STS(ph)LNERPK_
TSC2 Phosphorylation S1064 -0.927 _SLLGLDSGELQSGPESSSS(ph)PGVHVR_
TSC2 Phosphorylation S1248 -0.604 _SNTDSAVVMEEGS(ph)PGEVPVLVEPPGLEDVEAALGMDRR_
TSC2 Phosphorylation S1329 -0.120 _S(ph)SSSPELQTLQDILGDPGDK_
TSC2 Phosphorylation S1331 -0.262 _SSS(ph)SPELQTLQDILGDPGDKADVGR_
TSC2 Phosphorylation S1332 -0.063 _SSSS(ph)PELQTLQDILGDPGDK_
TSC2 Phosphorylation S1355 0.174 0.351 _ADVGRLS(ph)PEVK_
TSC2 Phosphorylation S1362 0.859 _S(ph)QSGTLDGESAAWSASGEDSR_
TSC2 Phosphorylation S1364 0.522 0.550 _SQS(ph)GTLDGESAAWSASGEDSR_
TSC2 Phosphorylation T1366 0.137 _SQSGT(ph)LDGESAAWSASGEDSR_
TSC2 Phosphorylation S1396 0.498 _S(ph)PSGLRPR_
TSC2 Phosphorylation S1743 0.596 _RLISS(ph)VEDFTEFV_
TWIST1 Ubiquitylation K150 -0.176 _IQTLK(gl)LAAR_
VANGL2 Ubiquitylation K379 0.582 _LQEEEQK(gl)NPR_
VASP Phosphorylation S239 0.625 -0.774 _VS(ph)KQEEASGGPTAPK_
WNT5A Ubiquitylation K268 -0.304 _VGDALK(gl)EK_
ZEB2 Phosphorylation S1124 0.491 _AYLQSITPQGYSDS(ph)EERESMPR_
ZIC2 Ubiquitylation K253 -0.697 0.374 _QQCIK(gl)QELICK_


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