bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: LRP6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LRP6 0 -0.221 0.210 0.050

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LRP6 Ubiquitylation K1443 -0.221 _GK(gl)SMISSLSIMGGSSGPPYDR_

Background Information for LRP6:


Pubmed-LRP6 »
Uniprot-LRP6 »
Biogrid-LRP6 »
ProteomicsDB-LRP6 »

Tumorportal-LRP6 »
COSMIC-LRP6 »
GenomeRNAi-LRP6 »
Genecards-LRP6


Protein-protein Interactions for LRP6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ADAM33 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHST9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CSNK1A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DKK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DKKL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ETV6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FCGRT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLK5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MGAT4C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PAPD7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PARP16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRSS37 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RASD2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RASSF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCGB1D1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SGK196 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SOST Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ST8SIA4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TAZ Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TGIF2LY Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WNT10B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LRP6
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members EG-like_dom IPR000742 1.74
Category members LDLR_classB_rpt IPR000033 0
Category members LDrepeatLR_classA_rpt IPR002172 0


Protein complexes (CORUM database) featuring LRP6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring LRP6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005769 early endosome Database 1.26
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_671 PID_WNT_CANONICAL_PATHWAY 0 0.64
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0021987 cerebral cortex development Database 0.37
Category members GO Category GO:0003344 pericardium morphogenesis Database 0.33
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0060021 palate development Database 0.23
Category members GO Category GO:0007268 synaptic transmission Database 0.23
Category members GO Category GO:0050680 negative regulation of epithelial cell proliferation Database 0.19
Category members GO Category GO:0009986 cell surface Database 0.17
Category members GO Category GO:0060349 bone morphogenesis Database 0.17
Category members GO Category GO:0045599 negative regulation of fat cell differentiation Database 0.13
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0030917 midbrain-hindbrain boundary development Database 0.11
Category members GO Category GO:0016055 Wnt signaling pathway Database 0.11
Category members GO Category GO:0021861 forebrain radial glial cell differentiation Database 0.1
Category members GO Category GO:0060596 mammary placode formation Database 0.1
Category members Pathway Pathway_679 KEGG_WNT_SIGNALING_PATHWAY 0 0.09
Category members GO Category GO:0001947 heart looping Database 0.08
Category members GO Category GO:0045598 regulation of fat cell differentiation Database 0.06
Category members GO Category GO:0042127 regulation of cell proliferation Database 0.06
Category members GO Category GO:0009952 anterior/posterior pattern specification Database 0.06
Category members GO Category GO:0045202 synapse Database 0.06
Category members GO Category GO:0034392 negative regulation of smooth muscle cell apoptotic process Database 0.05
Category members GO Category GO:0045787 positive regulation of cell cycle Database 0.04
Category members GO Category GO:0048699 generation of neurons Database 0.04
Category members GO Category GO:0043235 receptor complex Database 0.04
Category members GO Category GO:0001933 negative regulation of protein phosphorylation Database 0.04
Category members Pathway Pathway_942 PID_PS1_PATHWAY 0 0.03
Category members GO Category GO:0021915 neural tube development Database 0.03
Category members GO Category GO:0017147 Wnt-protein binding Database 0.02
Category members Pathway Pathway_1175 PID_BETA_CATENIN_DEG_PATHWAY 0 0.01
Category members GO Category GO:0051593 response to folic acid Database 0.01
Category members GO Category GO:0048596 embryonic camera-type eye morphogenesis Database 0.01
Category members Pathway Pathway_1277 PID_WNT_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_290 WNT_SIGNALING 0 0
Category members GO Category GO:0001702 gastrulation with mouth forming second Database 0
Category members GO Category GO:0001756 somitogenesis Database 0
Category members GO Category GO:0001843 neural tube closure Database 0
Category members GO Category GO:0002053 positive regulation of mesenchymal cell proliferation Database 0
Category members GO Category GO:0003401 axis elongation Database 0
Category members GO Category GO:0005041 low-density lipoprotein receptor activity Database 0
Category members GO Category GO:0005102 receptor binding Database 0
Category members GO Category GO:0005109 frizzled binding Database 0
Category members GO Category GO:0005901 caveola Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0006469 negative regulation of protein kinase activity Database 0
Category members GO Category GO:0007204 positive regulation of cytosolic calcium ion concentration Database 0
Category members GO Category GO:0009880 embryonic pattern specification Database 0
Category members GO Category GO:0009950 dorsal/ventral axis specification Database 0
Category members GO Category GO:0014033 neural crest cell differentiation Database 0
Category members GO Category GO:0016337 cell-cell adhesion Database 0
Category members GO Category GO:0019210 kinase inhibitor activity Database 0
Category members GO Category GO:0019534 toxin transporter activity Database 0
Category members GO Category GO:0021587 cerebellum morphogenesis Database 0
Category members GO Category GO:0021794 thalamus development Database 0
Category members GO Category GO:0021795 cerebral cortex cell migration Database 0
Category members GO Category GO:0021943 formation of radial glial scaffolds Database 0
Category members GO Category GO:0030178 negative regulation of Wnt signaling pathway Database 0
Category members GO Category GO:0030278 regulation of ossification Database 0
Category members GO Category GO:0030326 embryonic limb morphogenesis Database 0
Category members GO Category GO:0030900 forebrain development Database 0
Category members GO Category GO:0030901 midbrain development Database 0
Category members GO Category GO:0031410 cytoplasmic vesicle Database 0
Category members GO Category GO:0034185 apolipoprotein binding Database 0
Category members GO Category GO:0035108 limb morphogenesis Database 0
Category members GO Category GO:0035115 embryonic forelimb morphogenesis Database 0
Category members GO Category GO:0035116 embryonic hindlimb morphogenesis Database 0
Category members GO Category GO:0036342 post-anal tail morphogenesis Database 0
Category members GO Category GO:0042074 cell migration involved in gastrulation Database 0
Category members GO Category GO:0042475 odontogenesis of dentin-containing tooth Database 0
Category members GO Category GO:0042733 embryonic digit morphogenesis Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0042813 Wnt-activated receptor activity Database 0
Category members GO Category GO:0043025 neuronal cell body Database 0
Category members GO Category GO:0043434 response to peptide hormone Database 0
Category members GO Category GO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification Database 0
Category members GO Category GO:0045778 positive regulation of ossification Database 0
Category members GO Category GO:0045780 positive regulation of bone resorption Database 0
Category members GO Category GO:0046849 bone remodeling Database 0
Category members GO Category GO:0048705 skeletal system morphogenesis Database 0
Category members GO Category GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity Database 0
Category members GO Category GO:0060026 convergent extension Database 0
Category members GO Category GO:0060042 retina morphogenesis in camera-type eye Database 0
Category members GO Category GO:0060059 embryonic retina morphogenesis in camera-type eye Database 0
Category members GO Category GO:0060070 canonical Wnt signaling pathway Database 0
Category members GO Category GO:0060325 face morphogenesis Database 0
Category members GO Category GO:0060444 branching involved in mammary gland duct morphogenesis Database 0
Category members GO Category GO:0060535 trachea cartilage morphogenesis Database 0
Category members GO Category GO:0060603 mammary gland duct morphogenesis Database 0
Category members GO Category GO:0071397 cellular response to cholesterol Database 0


.

© Copyright Svejstrup Laboratory 2015