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cerebral cortex development
(GO:0021987)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
WDR62 2
TACC2 2 0.520 -0.920
PAFAH1B1 1 0.820 -0.330 1.632 0.711
NDE1 1
DICER1 1 -0.810 0.800 1.748 -0.207 -0.634
YWHAE 1 0.440 -0.380 1.095 -0.160
YWHAE 1 0.440 -0.380 1.129 0.621 0.321
BBS2 1 -0.810 0.820
TACC1 1 -0.060 -0.800
TACC3 0 1.030 -0.910
LRP6 0 0.210 0.050
PSEN1 0 0.930 -1.110
NCOA1 0 1.240 -0.460
BAX 0 1.590 -1.170 0.811 0.359
HIF1A 0 -0.480 0.400
PTPRS 0 0.140 0.270 -0.194 0.365
BTBD3 0 1.450 -0.720
ATIC 0 -0.830 0.480 -0.329 0.553
BBS4 0 0.310 0.160
MCPH1 0 -0.270 -0.170
CDK5 0 -1.100 1.740 -0.236 1.063 0.312
TSC1 0 1.100 -0.150
GNG12 0 1.160 -1.150 -1.317
GNG12 0 1.160 -1.150
FOXL1 0 0.560 -0.350 -1.217 -0.424 0.659
SOX2 0 -0.250 0.870
PLCB1 0 -0.300 -0.220
NF1 0 1.000 -0.500 0.444 -0.190
ATG7 0 -0.140 0.720 0.708
CCDC85C 0 0.000 0.220
CCDC85C 0 0.320 -0.860

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ATIC Ubiquitylation K195 -0.448 _K(gl)QYSKGVSQMPLR_
ATIC Ubiquitylation K199 -0.427 -0.247 _QYSK(gl)GVSQMPLR_
ATIC Ubiquitylation K397 0.429 _NNGVVDK(gl)SLFSNVVTK_
ATIC Ubiquitylation K406 0.213 0.405 _SLFSNVVTK(gl)NK_
ATIC Ubiquitylation K408 0.438 0.468 _SLFSNVVTKNK(gl)_
BAX Ubiquitylation K57 -1.174 _MGGEAPELALDPVPQDASTK(gl)K_
BAX Ubiquitylation K58 -1.718 -1.174 _MGGEAPELALDPVPQDASTKK(gl)_
BAX Ubiquitylation K64 0.708 1.306 _LSECLK(gl)R_
BBS2 Ubiquitylation K231 -0.482 _FGYALSNGTVGVYDK(gl)TSR_
BBS2 Ubiquitylation K360 -1.721 _NYEENAK(gl)AELASPLNEADGHR_
BBS2 Phosphorylation S365 2.366 _AELAS(ph)PLNEADGHR_
BBS2 Ubiquitylation K659 -0.582 _DLLNGYK(gl)IR_
BBS4 Ubiquitylation K28 -0.615 _TQFPVSTESQK(gl)PR_
BBS4 Ubiquitylation K302 -2.331 _YVAAISCLK(gl)R_
BBS4 Ubiquitylation K408 -2.242 _NALAQYQEMEK(gl)K_
BBS4 Ubiquitylation K409 -2.242 _NALAQYQEMEK(gl)K_
BTBD3 Ubiquitylation K352 0.438 _QDLALSIENK(gl)R_
BTBD3 Ubiquitylation K408 -0.868 _KPELQFVSK(gl)AR_
BTBD3 Ubiquitylation K446 -1.286 _CDSIQFAVDK(gl)R_
CCDC85C Phosphorylation S178 0.042 _S(ph)SIDSQASLSGPLSGGAPGAGAR_
CCDC85C Phosphorylation S179 0.042 _S(ph)SIDSQASLSGPLSGGAPGAGAR_
CCDC85C Ubiquitylation K285 0.218 _LLEGDK(gl)LLAQQAGSGEFR_
CDK5 Ubiquitylation K56 0.606 0.237 _EICLLK(gl)ELK_
FOXL1 Phosphorylation S6 0.325 0.055 _YS(ph)VSSPNSLGVVPYLGGEQSYYR_
FOXL1 Phosphorylation S235 -1.239 _TENGTCPS(ph)PPQPLS(ph)PAAALGSGSAAAVPK_
FOXL1 Phosphorylation S241 -1.239 _TENGTCPS(ph)PPQPLS(ph)PAAALGSGSAAAVPK_
FOXL1 Phosphorylation S259 -0.376 -0.198 _IES(ph)PDSSSSSLSSGSSPPGSLPSAR_
FOXL1 Phosphorylation S320 0.313 0.178 _GS(ph)PQSAAAELSSGLLASAAASSR_
FOXL1 Phosphorylation S323 0.347 _GSPQS(ph)AAAELSSGLLASAAASSR_
FOXL1 Ubiquitylation K554 -0.030 0.013 _TSGAFVYDCSK(gl)F_
GNG12 Ubiquitylation K4 0.230 0.493 _(ac)SSK(gl)TASTNNIAQAR_
GNG12 Ubiquitylation K34 0.515 1.067 _VSK(gl)ASADLMSYCEEHAR_
HIF1A Ubiquitylation K10 -1.686 _(ac)MEGAGGANDK(gl)K_
HIF1A Ubiquitylation K11 -1.686 _(ac)MEGAGGANDK(gl)K_
HIF1A Ubiquitylation K173 -0.662 _MK(gl)CTLTSR_
HIF1A Ubiquitylation K186 -0.590 _TMNIK(gl)SATWK_
HIF1A Ubiquitylation K252 -0.784 _HSLDM(ox)K(gl)FSYCDER_
HIF1A Ubiquitylation K371 -0.508 _PVESSDMK(gl)MTQLFTK_
HIF1A Ubiquitylation K378 -0.077 _MTQLFTK(gl)VESEDTSSLFDK_
HIF1A Ubiquitylation K390 -0.348 _VESEDTSSLFDK(gl)LKK_
HIF1A Ubiquitylation K392 -0.546 _VESEDTSSLFDKLK(gl)_
HIF1A Ubiquitylation K393 -0.451 _VESEDTSSLFDKLKK(gl)_
HIF1A Ubiquitylation K710 -1.696 _TTVPEEELNPK(gl)ILALQNAQR_
LRP6 Ubiquitylation K1443 -0.221 _GK(gl)SMISSLSIMGGSSGPPYDR_
MCPH1 Phosphorylation S333 -0.272 0.038 _YRLS(ph)PTLSSTK_
MCPH1 Phosphorylation T335 -0.306 _YRLSPT(ph)LSSTK_
NCOA1 Phosphorylation S22 0.503 0.810 _KGS(ph)PCDTLASSTEK_
NDE1 Ubiquitylation K270 2.830 _VGALESK(gl)LASCR_
NDE1 Phosphorylation S282 -0.767 -0.382 _NLVYDQS(ph)PNR_
NDE1 Phosphorylation S306 -2.156 _RPS(ph)STSVPLGDK_
NF1 Ubiquitylation K471 0.218 _MAPSLTFKEK(gl)_
NF1 Phosphorylation S864 -0.458 _SNSGLATYS(ph)PPMGPVSER_
NF1 Phosphorylation T2514 0.076 _GSEGYLAATYPTVGQT(ph)SPR_
NF1 Phosphorylation S2515 0.071 0.316 _GSEGYLAATYPTVGQTS(ph)PR_
NF1 Phosphorylation S2543 0.698 0.655 _S(ph)FDHLISDTK_
PAFAH1B1 Ubiquitylation K76 -0.530 _LNEAK(gl)EEFTSGGPLGQK_
PLCB1 Phosphorylation S1199 -0.494 _TPS(ph)SEELGGDIPGKEFDTPL_
PLCB1 Phosphorylation S1200 -0.483 _TPSS(ph)EELGGDIPGKEFDTPL_
PSEN1 Phosphorylation S313 0.844 _VSKNS(ph)KYNAESTER_
PSEN1 Ubiquitylation K314 0.016 0.414 _NSK(gl)YNAESTER_
PSEN1 Phosphorylation S366 -0.340 0.055 _AAVQELSS(ph)SILAGEDPEER_
PSEN1 Phosphorylation S367 0.005 0.066 _AAVQELSSS(ph)ILAGEDPEER_
PTPRS Ubiquitylation K1650 -0.595 -1.027 _LLASSK(gl)AHTSR_
PTPRS Ubiquitylation K1665 -0.790 _FISANLPCNK(gl)FK_
SOX2 Phosphorylation S251 0.157 -0.109 _SEASSS(ph)PPVVTSSSHSR_
TACC1 Phosphorylation S44 -0.293 -0.032 _GGAAGEDEAGGPEGDPEEEDS(ph)QAETK_
TACC1 Phosphorylation S91 0.291 1.551 _S(ph)QESQEADEQLVAEVVEK_
TACC1 Phosphorylation S94 1.530 _SQES(ph)QEADEQLVAEVVEK_
TACC2 Phosphorylation S2072 0.249 _RKS(ph)TDSVPISK_
TACC2 Phosphorylation S2226 1.598 2.720 _VQNS(ph)PPVGR_
TACC2 Phosphorylation S2512 1.543 1.249 _FSS(ph)PTEELDYR_
TACC2 Phosphorylation S2569 -1.730 _M(ox)SES(ph)PTPCSGSSFEETEALVNTAAK_
TACC3 Phosphorylation S25 -0.993 -0.186 _NTENCDFLFS(ph)PPEVTGR_
TACC3 Phosphorylation T59 -2.436 _VTFQT(ph)PLRDPQTHR_
TACC3 Phosphorylation S71 0.876 1.139 _ILS(ph)PSMASK_
TACC3 Phosphorylation S175 0.134 0.059 _VS(ph)GSPEQAVEENLSSYSLDR_
TACC3 Phosphorylation S177 0.248 0.430 _VSGS(ph)PEQAVEENLSSYSLDRR_
TACC3 Phosphorylation T228 0.779 _AETPHGAEEECKAET(ph)PHGAEEECR_
TACC3 Phosphorylation T249 -0.679 -0.649 _HGGVCAPAAVAT(ph)SPPGAIPK_
TACC3 Phosphorylation S250 -0.740 -0.589 _HGGVCAPAAVATS(ph)PPGAIPK_
TACC3 Phosphorylation T315 1.424 _AM(ox)T(ph)LSPQEEVAAGQMASSSR_
TACC3 Phosphorylation S317 1.040 1.242 _AM(ox)TLS(ph)PQEEVAAGQM(ox)ASSSR_
TACC3 Phosphorylation S434 0.179 0.184 _SGCSEAQPPES(ph)PETR_
TACC3 Ubiquitylation K649 -0.831 _DLDAVVK(gl)ATQEENR_
TACC3 Ubiquitylation K819 0.067 _TK(gl)ENEELTR_
TSC1 Phosphorylation S505 0.141 0.350 _GGFDS(ph)PFYR_
WDR62 Phosphorylation S32 -1.724 -1.340 _RGQS(ph)SPPPAPPICLR_
WDR62 Phosphorylation S33 -0.818 -1.182 _RGQSS(ph)PPPAPPICLR_
WDR62 Phosphorylation S49 0.012 _TRLS(ph)TASEETVQNR_
WDR62 Phosphorylation S1070 0.700 _HHFETLTES(ph)PCR_
WDR62 Phosphorylation S1123 1.354 1.533 _ATQCLVKS(ph)PEVK_
WDR62 Phosphorylation T1140 0.715 1.046 _AGT(ph)GYASPDRTHVLAAGK_
WDR62 Phosphorylation S1144 0.823 1.189 _AGTGYAS(ph)PDRTHVLAAGK_
WDR62 Phosphorylation S1226 -0.377 -0.367 _S(ph)ISLGDSEGPIVATLAQPLR_
WDR62 Phosphorylation S1228 -0.358 -0.330 _SIS(ph)LGDSEGPIVATLAQPLR_
WDR62 Phosphorylation S1248 -1.061 -1.122 _RPS(ph)SVGELASLGQELQAITTATTPSLDSEGQEPALR_
WDR62 Phosphorylation S1249 -1.023 -1.122 _RPSS(ph)VGELASLGQELQAITTATT(ph)PSLDSEGQEPALR_
WDR62 Phosphorylation S1255 -1.122 _RPSSVGELAS(ph)LGQELQAITTATTPSLDSEGQEPALR_
WDR62 Phosphorylation T1268 1.841 _RPS(ph)SVGELASLGQELQAITTATT(ph)PSLDSEGQEPALR_
WDR62 Phosphorylation S1348 -1.872 _LHGSAFRPSLPAPES(ph)PGLPAHPSNPQLPEAR_
YWHAE Ubiquitylation K38 0.710 1.822 _YDEMVESMK(gl)K_
YWHAE Ubiquitylation K39 1.734 _YDEMVESMKK(gl)_
YWHAE Ubiquitylation K60 0.554 1.732 _NLLSVAYK(gl)NVIGAR_
YWHAE Ubiquitylation K83 0.375 0.643 _IISSIEQKEENK(gl)GGEDKLK_
YWHAE Ubiquitylation K90 1.103 _GGEDKLK(gl)MIR_
YWHAE Ubiquitylation K116 -0.289 _LICCDILDVLDK(gl)HLIPAANTGESK_
YWHAE Ubiquitylation K133 0.653 1.264 _VFYYK(gl)M(ox)K_
YWHAE Ubiquitylation K152 0.031 0.601 _K(gl)EAAENSLVAYK_
YWHAE Phosphorylation S210 0.534 0.506 _AAFDDAIAELDTLS(ph)EESYK_
YWHAE Phosphorylation S213 0.541 _AAFDDAIAELDTLSEES(ph)YK_


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