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Query: BBS2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
BBS2 1 2.704 -0.810 0.820

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
BBS2 Phosphorylation S365 2.366 _AELAS(ph)PLNEADGHR_
BBS2 Ubiquitylation K231 -0.482 _FGYALSNGTVGVYDK(gl)TSR_
BBS2 Ubiquitylation K659 -0.582 _DLLNGYK(gl)IR_
BBS2 Ubiquitylation K360 -1.721 _NYEENAK(gl)AELASPLNEADGHR_

Background Information for BBS2:


Pubmed-BBS2 »
Uniprot-BBS2 »
Biogrid-BBS2 »
ProteomicsDB-BBS2 »

Tumorportal-BBS2 »
COSMIC-BBS2 »
GenomeRNAi-BBS2 »
Genecards-BBS2


Protein-protein Interactions for BBS2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BBS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BBS5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BBS7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GUCY1B3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LZTFL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NME3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIM44 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in BBS2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39


Protein complexes (CORUM database) featuring BBS2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring BBS2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0008104 protein localization Database 0.5
Category members GO Category GO:0021987 cerebral cortex development Database 0.37
Category members GO Category GO:0001103 RNA polymerase II repressing transcription factor binding Database 0.36
Category members GO Category GO:0043001 Golgi to plasma membrane protein transport Database 0.32
Category members GO Category GO:0042311 vasodilation Database 0.29
Category members GO Category GO:0034464 BBSome Database 0.1
Category members GO Category GO:0060296 regulation of cilium beat frequency involved in ciliary motility Database 0.08
Category members GO Category GO:0014824 artery smooth muscle contraction Database 0.07
Category members GO Category GO:0007288 sperm axoneme assembly Database 0.06
Category members Disease phenotype BARDET-BIEDL_SYNDROME BARDET-BIEDL SYNDROME Database 0
Category members GO Category GO:0005932 microtubule basal body Database 0
Category members GO Category GO:0007601 visual perception Database 0
Category members GO Category GO:0010629 negative regulation of gene expression Database 0
Category members GO Category GO:0021756 striatum development Database 0
Category members GO Category GO:0021766 hippocampus development Database 0
Category members GO Category GO:0030534 adult behavior Database 0
Category members GO Category GO:0031514 motile cilium Database 0
Category members GO Category GO:0032402 melanosome transport Database 0
Category members GO Category GO:0033210 leptin-mediated signaling pathway Database 0
Category members GO Category GO:0033365 protein localization to organelle Database 0
Category members GO Category GO:0035058 nonmotile primary cilium assembly Database 0
Category members GO Category GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway Database 0
Category members GO Category GO:0040015 negative regulation of multicellular organism growth Database 0
Category members GO Category GO:0040018 positive regulation of multicellular organism growth Database 0
Category members GO Category GO:0042384 cilium assembly Database 0
Category members GO Category GO:0044321 response to leptin Database 0
Category members GO Category GO:0045444 fat cell differentiation Database 0
Category members GO Category GO:0045494 photoreceptor cell maintenance Database 0
Category members GO Category GO:0048854 brain morphogenesis Database 0
Category members GO Category GO:0051216 cartilage development Database 0
Category members GO Category GO:0060170 ciliary membrane Database 0
Category members GO Category GO:0060271 cilium morphogenesis Database 0


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