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Query: NDE1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NDE1 1 1.681

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NDE1 Phosphorylation S282 -0.767 -0.382 _NLVYDQS(ph)PNR_
NDE1 Phosphorylation S306 -2.156 _RPS(ph)STSVPLGDK_
NDE1 Ubiquitylation K270 2.830 _VGALESK(gl)LASCR_

Background Information for NDE1:


Pubmed-NDE1 »
Uniprot-NDE1 »
Biogrid-NDE1 »
ProteomicsDB-NDE1 »

Tumorportal-NDE1 »
COSMIC-NDE1 »
GenomeRNAi-NDE1 »
Genecards-NDE1


Protein-protein Interactions for NDE1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CALML3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CSNK2A2 Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM190B Cat. description Hein, Mann, Cell 2015
Category members IP bait GPKOW Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF20B Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NDE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NDEL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PAFAH1B1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ARC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C17orf59 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CGNL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM167A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM190A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait JUNB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA1984 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NDEL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUP54 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNAP29 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCL1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCP10L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TEKT4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIM27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSNARE1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NDE1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members NUDE_C IPR006964 0


Protein complexes (CORUM database) featuring NDE1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NDE1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0000776 kinetochore Database 2.24
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0032154 cleavage furrow Database 2.01
Category members GO Category GO:0019904 protein domain specific binding Database 1.85
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0008017 microtubule binding Database 0.79
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0005819 spindle Database 0.41
Category members GO Category GO:0005815 microtubule organizing center Database 0.39
Category members GO Category GO:0031023 microtubule organizing center organization Database 0.38
Category members GO Category GO:0021987 cerebral cortex development Database 0.37
Category members GO Category GO:0000086 G2/M transition of mitotic cell cycle Database 0.33
Category members GO Category GO:0000777 condensed chromosome kinetochore Database 0.32
Category members GO Category GO:0000132 establishment of mitotic spindle orientation Database 0.29
Category members GO Category GO:0007405 neuroblast proliferation Database 0.28
Category members GO Category GO:0031616 spindle pole centrosome Database 0.27
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0047496 vesicle transport along microtubule Database 0.19
Category members GO Category GO:0001764 neuron migration Database 0
Category members GO Category GO:0007020 microtubule nucleation Database 0
Category members GO Category GO:0030900 forebrain development Database 0
Category members GO Category GO:0051298 centrosome duplication Database 0
Category members GO Category GO:0051303 establishment of chromosome localization Database 0


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