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Query: TACC3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TACC3 0 1.902 1.030 -0.910

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TACC3 Phosphorylation S317 1.040 1.242 _AM(ox)TLS(ph)PQEEVAAGQM(ox)ASSSR_
TACC3 Phosphorylation S71 0.876 1.139 _ILS(ph)PSMASK_
TACC3 Phosphorylation T228 0.779 _AETPHGAEEECKAET(ph)PHGAEEECR_
TACC3 Phosphorylation S177 0.248 0.430 _VSGS(ph)PEQAVEENLSSYSLDRR_
TACC3 Phosphorylation S434 0.179 0.184 _SGCSEAQPPES(ph)PETR_
TACC3 Phosphorylation S175 0.134 0.059 _VS(ph)GSPEQAVEENLSSYSLDR_
TACC3 Phosphorylation S25 -0.993 -0.186 _NTENCDFLFS(ph)PPEVTGR_
TACC3 Phosphorylation S250 -0.740 -0.589 _HGGVCAPAAVATS(ph)PPGAIPK_
TACC3 Phosphorylation T249 -0.679 -0.649 _HGGVCAPAAVAT(ph)SPPGAIPK_
TACC3 Ubiquitylation K649 -0.831 _DLDAVVK(gl)ATQEENR_
TACC3 Phosphorylation T59 -2.436 _VTFQT(ph)PLRDPQTHR_
TACC3 Phosphorylation T315 1.424 _AM(ox)T(ph)LSPQEEVAAGQMASSSR_
TACC3 Ubiquitylation K819 0.067 _TK(gl)ENEELTR_

Background Information for TACC3:


Pubmed-TACC3 »
Uniprot-TACC3 »
Biogrid-TACC3 »
ProteomicsDB-TACC3 »

Tumorportal-TACC3 »
COSMIC-TACC3 »
GenomeRNAi-TACC3 »
Genecards-TACC3


Protein-protein Interactions for TACC3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ARX Cat. description Hein, Mann, Cell 2015
Category members IP bait BOD1L1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CKAP5 Cat. description Hein, Mann, Cell 2015
Category members IP bait SLAIN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TACC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait AURKA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C17orf59 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CORO6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CRISP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EVL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GTF2E2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSPA8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSPBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MVK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OIP5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLEKHO2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLAIN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNAP29 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPERT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZFC3H1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TACC3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TACC IPR007707 0.21


Protein complexes (CORUM database) featuring TACC3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5373 Chromatin remodeling complex (TACC2, TACC3, PCAF) Database 0.52


Categories featuring TACC3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0019904 protein domain specific binding Database 1.85
Category members Pathway Pathway_924 PID_ILK_PATHWAY 0 1.75
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0000226 microtubule cytoskeleton organization Database 0.5
Category members GO Category GO:0021987 cerebral cortex development Database 0.37
Category members Pathway Pathway_985 PID_AURORA_A_PATHWAY 0 0.34
Category members GO Category GO:0032886 regulation of microtubule-based process Database 0.29
Category members GO Category GO:0022008 neurogenesis Database 0.16
Category members Disease phenotype Giant_cell_glioblastoma Giant cell glioblastoma Database 0.14
Category members Disease phenotype Gliosarcoma Gliosarcoma Database 0.14
Category members GO Category GO:0042994 cytoplasmic sequestering of transcription factor Database 0.14
Category members GO Category GO:0051726 regulation of cell cycle Database 0.11
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0030953 astral microtubule organization Database 0.01
Category members GO Category GO:0022027 interkinetic nuclear migration Database 0.01
Category members GO Category GO:0001666 response to hypoxia Database 0
Category members GO Category GO:0006950 response to stress Database 0
Category members GO Category GO:0030097 hemopoiesis Database 0


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