bioLOGIC-db

bioLOGIC Data

Query: PLXNB2

[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
PLXNB2	0	2.291	1.170	-1.050				0.924	0.330
PLXNB2	0	2.291	1.170	-1.050				1.011	0.828

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV (PI)	Sequence
PLXNB2	Ubiquitylation	K76	0.452	_LQLEQQVATGPALDNK(gl)K_
PLXNB2	Ubiquitylation	K77	0.452	_LQLEQQVATGPALDNK(gl)K_
PLXNB2	Ubiquitylation	K747	0.202	_SYGK(gl)NIDSK_
PLXNB2	Ubiquitylation	K1442	-0.119	_GPVDAVQK(gl)K_
PLXNB2	Ubiquitylation	K1443	-0.119	_GPVDAVQK(gl)K_
PLXNB2	Ubiquitylation	K1738	-0.751	_DSPSNK(gl)LLYAK_

ProteomicsDB-PLXNB2 »

Protein-protein Interactions for PLXNB2

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait ADAM21	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait BTNL8	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait DEFA1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait DEFA5	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait IL17RC	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait IL27RA	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait LMAN2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait LYPD6	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait MPPE1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait PTCH1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait RHOD	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait SCGB1D1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ST8SIA4	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait TLR1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait TMED6	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait TMPRSS3	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait TMX1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in PLXNB2

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	Rho_GTPase_activation_prot	IPR008936	0.53
Category members	Plexin_cytoplasmic_RasGAP_dom	IPR013548	0.31
Category members	IPT	IPR002909	0.11
Category members	Semap_dom	IPR001627	0.04
Category members	Plexin_repeat	IPR002165	0
Category members	Ig_E-set	IPR014756	0
Category members	Plexin-like_fold	IPR016201	0

Protein complexes (CORUM database) featuring PLXNB2

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)

Categories featuring PLXNB2

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	DDR Literature	pubmedid:19647519	Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation		3.6
Category members	GO Category	GO:0005887	integral to plasma membrane	Database	1.69
Category members	GO Category	GO:0016020	membrane	Database	0.52
Category members	GO Category	GO:0005622	intracellular	Database	0.32
Category members	GO Category	GO:0007275	multicellular organismal development	Database	0.31
Category members	GO Category	GO:0017154	semaphorin receptor activity	Database	0.31
Category members	GO Category	GO:0007405	neuroblast proliferation	Database	0.28
Category members	GO Category	GO:0005096	GTPase activator activity	Database	0.19
Category members	GO Category	GO:0032319	regulation of Rho GTPase activity	Database	0.14
Category members	GO Category	GO:0001932	regulation of protein phosphorylation	Database	0.04
Category members	Pathway	Pathway_1034	KEGG_AXON_GUIDANCE	0	0.04
Category members	GO Category	GO:0001843	neural tube closure	Database	0
Category members	GO Category	GO:0004872	receptor activity	Database	0
Category members	GO Category	GO:0007165	signal transduction	Database	0
Category members	GO Category	GO:0007420	brain development	Database	0
Category members	GO Category	GO:0008360	regulation of cell shape	Database	0
Category members	GO Category	GO:0050772	positive regulation of axonogenesis	Database	0