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Query: NCKAP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NCKAP1 0 2.010 1.120 -0.620 0.347 0.023 -0.306 1.181 0.448

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NCKAP1 Ubiquitylation K190 -0.009 _LGQMIVDYENPLK(gl)K_
NCKAP1 Ubiquitylation K191 -0.009 _LGQMIVDYENPLK(gl)K_
NCKAP1 Ubiquitylation K12 -1.114 -0.228 _SVLQPSQQK(gl)LAEK_
NCKAP1 Ubiquitylation K1075 -0.817 _IGQETDK(gl)TTTR_
NCKAP1 Ubiquitylation K16 0.326 _LAEK(gl)LTILNDR_

Background Information for NCKAP1:


Pubmed-NCKAP1 »
Uniprot-NCKAP1 »
Biogrid-NCKAP1 »
ProteomicsDB-NCKAP1 »

Tumorportal-NCKAP1 »
COSMIC-NCKAP1 »
GenomeRNAi-NCKAP1 »
Genecards-NCKAP1


Protein-protein Interactions for NCKAP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ABI1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NHSL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ABI2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AMZ1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BAIAP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C10orf88 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CBLC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CGB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COG6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DTNBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GJB7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HOMER3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSPB9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IKBIP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA0355 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NHSL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TIMM50 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UBXN11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WASF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF511 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NCKAP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Nck-associated_protein-1 IPR019137 0.04


Protein complexes (CORUM database) featuring NCKAP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 186 Wave-2 complex Database 0.08
Category members Corum 2300 Profilin 2 complex Database 0


Categories featuring NCKAP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members Pathway Pathway_292 PID_ECADHERIN_NASCENT_AJ_PATHWAY 0 2.74
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members Pathway Pathway_579 PID_ERBB1_DOWNSTREAM_PATHWAY 0 1.97
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members Pathway Pathway_466 PID_ECADHERIN_STABILIZATION_PATHWAY 0 1.4
Category members Pathway Pathway_561 PID_PDGFRB_PATHWAY 0 1.18
Category members Pathway Pathway_669 PID_RAC1_PATHWAY 0 0.68
Category members GO Category GO:0030032 lamellipodium assembly Database 0.66
Category members GO Category GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis Database 0.33
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members GO Category GO:0031258 lamellipodium membrane Database 0.15
Category members GO Category GO:0048339 paraxial mesoderm development Database 0.09
Category members Pathway Pathway_580 KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 0 0.08
Category members GO Category GO:0007492 endoderm development Database 0.06
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members GO Category GO:0050821 protein stabilization Database 0.04
Category members Pathway Pathway_912 BIOCARTA_ACTINY_PATHWAY 0 0
Category members GO Category GO:0001756 somitogenesis Database 0
Category members GO Category GO:0001843 neural tube closure Database 0
Category members GO Category GO:0007354 zygotic determination of anterior/posterior axis, embryo Database 0
Category members GO Category GO:0007417 central nervous system development Database 0
Category members GO Category GO:0008078 mesodermal cell migration Database 0
Category members GO Category GO:0010172 embryonic body morphogenesis Database 0
Category members GO Category GO:0030903 notochord development Database 0
Category members GO Category GO:0030950 establishment or maintenance of actin cytoskeleton polarity Database 0
Category members GO Category GO:0032880 regulation of protein localization Database 0
Category members GO Category GO:0035050 embryonic heart tube development Database 0
Category members GO Category GO:0042074 cell migration involved in gastrulation Database 0
Category members GO Category GO:0045175 basal protein localization Database 0
Category members GO Category GO:0045176 apical protein localization Database 0
Category members GO Category GO:0048340 paraxial mesoderm morphogenesis Database 0
Category members GO Category GO:0048570 notochord morphogenesis Database 0
Category members GO Category GO:0048617 embryonic foregut morphogenesis Database 0


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