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Query: HECTD1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HECTD1 1 0.816 -0.730 0.420 0.181 -1.016 -0.692

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HECTD1 Ubiquitylation K2605 0.861 _LLAATMEK(gl)GFHLN_
HECTD1 Phosphorylation S631 -0.150 _VSTLAGPS(ph)SDDENEEESKPEKEDEPQEDAK_
HECTD1 Phosphorylation S632 -0.423 -0.150 _VSTLAGPSS(ph)DDENEEESKPEKEDEPQEDAK_
HECTD1 Ubiquitylation K1272 -0.167 _SQVLK(gl)YMVPGAR_
HECTD1 Ubiquitylation K255 -0.575 -0.414 _MAAAGGTVSGPSSACK(gl)PGR_
HECTD1 Ubiquitylation K1287 -0.787 -0.617 _GLDWK(gl)WR_
HECTD1 Ubiquitylation K1371 -0.621 _NNCPDK(gl)TSAAAGSSSR_
HECTD1 Ubiquitylation K340 1.634 _KALPK(gl)SSAGSTGR_
HECTD1 Ubiquitylation K1253 -0.263 _AAK(gl)EAEANLRR_
HECTD1 Ubiquitylation K1382 0.103 _K(gl)GSSSSVCSVASSSDISLGSTK_
HECTD1 Ubiquitylation K1768 -0.397 _TWDDDYVLK(gl)R_
HECTD1 Ubiquitylation K2471 -0.108 _DGFNK(gl)VFPMEK_

Background Information for HECTD1:


Pubmed-HECTD1 »
Uniprot-HECTD1 »
Biogrid-HECTD1 »
ProteomicsDB-HECTD1 »

Tumorportal-HECTD1 »
COSMIC-HECTD1 »
GenomeRNAi-HECTD1 »
Genecards-HECTD1


Protein-protein Interactions for HECTD1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AARSD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BMP15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAMKMT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAPN6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CINP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPB41L5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GMNN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIF1AN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TTLL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF223 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF695 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HECTD1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members Coagulation_fac_5/8-C_type_dom IPR000421 0.13
Category members HECT IPR000569 0.04
Category members Ankyrin_rpt IPR002110 0
Category members Galactose-bd-like IPR008979 0
Category members Mib_Herc2 IPR010606 0
Category members Sad1_UNC_C IPR012919 0
Category members Ankyrin_rpt-contain_dom IPR020683 0


Protein complexes (CORUM database) featuring HECTD1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HECTD1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process Database 0.27
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members GO Category GO:0001843 neural tube closure Database 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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