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Results for the Category
HECT
(IPR000569)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
HUWE1 3 -1.250 1.500
HUWE1 3 -1.250 1.500 -0.684 0.362 -0.152
HERC1 3 -1.750 2.210
UBE3A 2 -0.310 -0.470
HERC4 2 2.840 -1.140 -0.379
TRIP12 2 -1.630 2.710 -0.585 -0.217
TRIP12 2 -1.630 2.710 0.578 0.523
ITCH 1 1.000 -0.610 -0.346 0.023 0.613
HECTD1 1 -0.730 0.420 0.181 -1.016 -0.692
UBR5 1 0.470 -0.820 -0.310
UBR5 1 0.470 -0.820 -1.380
UBR5 1 0.470 -0.820 0.046 0.305 0.536 -0.482
WWP1 1 -1.400 1.340
WWP1 1 0.850 -1.030
WWP1 1 -1.400 1.340 -0.346 0.023 0.613
WWP1 1 0.850 -1.030 -0.346 0.023 0.613
UBE3C 0 1.470 -0.710 -0.022 -0.743
NEDD4L 0 -0.050 -0.110
NEDD4 0 -1.320 1.730
G2E3 0 1.130 -0.800
HECTD3 0 -0.230 0.290 -0.803
HECW2 0 0.150 0.240
HERC3 0 -1.630 2.450
HERC6 0 -0.070 0.630
HERC5 0 -0.330 1.710
HECTD4 0 -0.250 -0.070 0.493
HECTD4 0 0.600 -0.690 0.493

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
G2E3 Ubiquitylation K327 -1.736 _GIIYNSGEFQK(gl)AK_
G2E3 Ubiquitylation K329 -0.498 _GIIYNSGEFQKAK(gl)_
G2E3 Ubiquitylation K363 -1.044 _QSPGSQSK(gl)DLLR_
HECTD1 Ubiquitylation K255 -0.575 -0.414 _MAAAGGTVSGPSSACK(gl)PGR_
HECTD1 Ubiquitylation K340 1.634 _KALPK(gl)SSAGSTGR_
HECTD1 Phosphorylation S631 -0.150 _VSTLAGPS(ph)SDDENEEESKPEKEDEPQEDAK_
HECTD1 Phosphorylation S632 -0.423 -0.150 _VSTLAGPSS(ph)DDENEEESKPEKEDEPQEDAK_
HECTD1 Ubiquitylation K1253 -0.263 _AAK(gl)EAEANLRR_
HECTD1 Ubiquitylation K1272 -0.167 _SQVLK(gl)YMVPGAR_
HECTD1 Ubiquitylation K1287 -0.787 -0.617 _GLDWK(gl)WR_
HECTD1 Ubiquitylation K1371 -0.621 _NNCPDK(gl)TSAAAGSSSR_
HECTD1 Ubiquitylation K1382 0.103 _K(gl)GSSSSVCSVASSSDISLGSTK_
HECTD1 Ubiquitylation K1768 -0.397 _TWDDDYVLK(gl)R_
HECTD1 Ubiquitylation K2471 -0.108 _DGFNK(gl)VFPMEK_
HECTD1 Ubiquitylation K2605 0.861 _LLAATMEK(gl)GFHLN_
HECTD3 Ubiquitylation K322 -0.493 _RVVVYGGEGDNLKK(gl)_
HECTD4 Phosphorylation S1381 -0.092 _S(ph)M(ox)SAPSDLEM(ox)IGNEDLEFTR_
HECTD4 Phosphorylation S1383 0.182 0.168 _SM(ox)S(ph)APSDLEMIGNEDLEFTR_
HECTD4 Phosphorylation T2356 -0.536 -1.023 _TEGT(ph)PPPPGQPAK_
HECW2 Phosphorylation S48 0.133 0.276 _ANS(ph)DTDLVTSESR_
HERC1 Phosphorylation S1428 0.599 2.067 _RVS(ph)TDLPEGQDVYTAACNSVIHR_
HERC1 Phosphorylation S2720 0.776 0.232 _RQS(ph)LTSPDSQSAR_
HERC1 Ubiquitylation K2769 0.446 2.108 _QIAK(gl)AMEATGAR_
HERC1 Ubiquitylation K2881 0.928 1.146 _HK(gl)FDLAAR_
HERC1 Ubiquitylation K3355 0.181 _LRPNYDK(gl)SEVEK_
HERC1 Ubiquitylation K3837 0.055 _TALK(gl)QQGVLGLNMAPCMR_
HERC1 Phosphorylation S4393 5.329 _EVS(ph)IHTVRAR_
HERC1 Ubiquitylation K4462 -1.280 -0.797 _SIGK(gl)TMVQGK_
HERC3 Ubiquitylation K870 0.160 _ESYGVIEQK(gl)K_
HERC4 Ubiquitylation K176 -0.279 _YGQLGLGTDCK(gl)K_
HERC4 Ubiquitylation K177 1.820 _YGQLGLGTDCKK(gl)_
HERC5 Ubiquitylation K397 -3.968 _TIPTLNEGTVK(gl)R_
HERC5 Ubiquitylation K406 -1.155 _WIADVETK(gl)R_
HERC6 Ubiquitylation K276 -0.341 _SGQLGYSPTPEK(gl)R_
HUWE1 Ubiquitylation K27 -1.058 _ALIDKLK(gl)_
HUWE1 Phosphorylation S131 0.155 _IQRPNTTQEGEEMETDMDVADVAMESS(ph)PGSSISMEHR_
HUWE1 Ubiquitylation K324 1.996 _QLMEIK(gl)AASLR_
HUWE1 Ubiquitylation K516 1.194 _SMLNFLK(gl)K_
HUWE1 Ubiquitylation K517 1.194 _SMLNFLK(gl)K_
HUWE1 Phosphorylation S648 0.066 _RS(ph)SDPLGDTASNLGSAVDELMR_
HUWE1 Phosphorylation S649 0.305 _RSS(ph)DPLGDTASNLGSAVDELMR_
HUWE1 Ubiquitylation K674 -0.756 0.052 _HQPTLK(gl)TDATTAIIK_
HUWE1 Ubiquitylation K701 -0.689 0.009 _YICQK(gl)PSIQK_
HUWE1 Ubiquitylation K1037 -0.044 _SK(gl)ITPAMAAR_
HUWE1 Ubiquitylation K1107 0.382 0.570 _STASALTK(gl)LLTK_
HUWE1 Ubiquitylation K1111 -2.104 _LLTK(gl)GLSWQPPPYTPTPR_
HUWE1 Phosphorylation S1368 2.745 2.124 _DLS(ph)MSEEDQM(ox)M(ox)R_
HUWE1 Phosphorylation S1395 0.200 0.293 _AES(ph)PEEVACRK_
HUWE1 Ubiquitylation K1470 0.459 0.499 _VCDLIMTAIK(gl)R_
HUWE1 Ubiquitylation K1608 0.575 -0.055 _AQMTK(gl)YLQSNSNNWR_
HUWE1 Ubiquitylation K1708 -0.283 _TLEESK(gl)EMDIK_
HUWE1 Ubiquitylation K1713 0.810 _TLEESKEMDIK(gl)R_
HUWE1 Phosphorylation T1722 1.903 0.188 _GNDT(ph)PLALESTNTEK_
HUWE1 Ubiquitylation K1840 0.879 0.090 _HTMEK(gl)VVR_
HUWE1 Phosphorylation S1903 0.533 0.300 _GS(ph)GTASDDEFENLR_
HUWE1 Phosphorylation T1905 0.542 0.300 _GSGT(ph)ASDDEFENLR_
HUWE1 Phosphorylation S1907 0.685 0.593 _GSGTAS(ph)DDEFENLR_
HUWE1 Ubiquitylation K1917 -1.189 -0.700 _IK(gl)GPNAVQLVK_
HUWE1 Ubiquitylation K2172 0.867 -0.078 _ALAMAESTEK(gl)HAR_
HUWE1 Ubiquitylation K2219 -0.368 0.472 _K(gl)GLVNDLAR_
HUWE1 Ubiquitylation K2267 -0.095 -0.110 _IVNQPSSLFGSK(gl)SASSK_
HUWE1 Phosphorylation S2362 0.398 0.411 _DGGS(ph)GNSTIIVSR_
HUWE1 Phosphorylation S2372 0.517 _S(ph)GEDESQEDVLMDEAPSNLSQASTLQANR_
HUWE1 Phosphorylation S2377 0.768 _SGEDES(ph)QEDVLMDEAPSNLSQASTLQANR_
HUWE1 Phosphorylation S2532 0.684 _HADHSSLTLGS(ph)GSSTTR_
HUWE1 Ubiquitylation K2703 -0.653 _QLAEEETK(gl)ITDK_
HUWE1 Phosphorylation S2887 -0.764 -0.940 _AGS(ph)STPGDAPPAVAEVQGR_
HUWE1 Phosphorylation T2889 1.022 0.924 _AGSST(ph)PGDAPPAVAEVQGR_
HUWE1 Phosphorylation S2917 -1.340 _SDGSGESAQPPEDS(ph)SPPASSESSSTR_
HUWE1 Phosphorylation S2918 -1.072 -1.081 _SDGSGESAQPPEDSS(ph)PPASSESSSTR_
HUWE1 Ubiquitylation K3244 -0.067 _SSESELCIETPK(gl)LTTSEEK_
HUWE1 Ubiquitylation K3345 0.581 0.528 _HVLDTLIQLAK(gl)_
HUWE1 Phosphorylation S3373 0.040 0.333 _ACS(ph)PCSSQSSSSGICTDFWDLLVK_
HUWE1 Ubiquitylation K3452 0.345 0.352 _SSLLTEK(gl)LLR_
HUWE1 Ubiquitylation K3558 -0.045 -0.283 _SPAK(gl)VSDGGSSSTDFK_
HUWE1 Ubiquitylation K3621 -0.956 _DTVLK(gl)LLLNGAR_
HUWE1 Phosphorylation S3662 0.940 0.734 _AQCETLS(ph)PDGLPEEQPQTTK_
HUWE1 Ubiquitylation K3677 -1.251 -1.639 _AQCETLSPDGLPEEQPQTTKLK(gl)_
HUWE1 Ubiquitylation K3716 -0.483 _ELQLPSMSMLTSK(gl)TSTQK_
HUWE1 Phosphorylation S3752 0.910 0.498 _LGS(ph)SGLGSASSIQAAVR_
HUWE1 Phosphorylation S3753 1.473 0.728 _LGSS(ph)GLGSASSIQAAVR_
HUWE1 Phosphorylation S3757 0.931 0.989 _LGSSGLGS(ph)ASSIQAAVR_
HUWE1 Phosphorylation S3816 -0.580 -0.661 _REESPMDVDQPS(ph)PSAQDTQSIASDGTPQGEK_
HUWE1 Phosphorylation S3906 -1.731 -2.374 _ES(ph)QLAHIKDEPPPLSPAPLTPATPSSLDPFFSR_
HUWE1 Phosphorylation S3919 -1.085 -1.773 _ESQLAHIKDEPPPLS(ph)PAPLTPATPSSLDPFFSR_
HUWE1 Ubiquitylation K3954 -2.295 -1.326 _EPSSMHISSSLPPDTQK(gl)FLR_
HUWE1 Ubiquitylation K3997 0.639 0.630 _VLDFDVK(gl)R_
HUWE1 Ubiquitylation K4014 0.012 _LDEGLRK(gl)EDMAVHVR_
HUWE1 Ubiquitylation K4116 0.312 _IVAK(gl)AVYDNR_
HUWE1 Ubiquitylation K4295 0.703 0.688 _AK(gl)FLQFVTGTSK_
ITCH Ubiquitylation K66 -0.890 _WK(gl)QPLTVIVTPVSK_
ITCH Ubiquitylation K350 0.049 0.396 _VYYVDHVEK(gl)R_
ITCH Ubiquitylation K446 -1.514 -1.539 _EFDPLGPLPPGWEK(gl)R_
ITCH Ubiquitylation K478 -1.265 _SQGQLNEK(gl)PLPEGWEMR_
ITCH Ubiquitylation K513 -0.564 1.593 _TGK(gl)SALDNGPQIAYVR_
ITCH Ubiquitylation K861 -0.810 0.596 _VGK(gl)ENWLPR_
NEDD4 Phosphorylation Y751 -0.924 _RGSLQAY(ph)TFEEQPTLPVLLPTSSGLPPGWEEK_
NEDD4 Ubiquitylation K874 0.127 _LK(gl)IPAHLR_
NEDD4 Ubiquitylation K882 -0.919 0.114 _GK(gl)TSLDTSNDLGPLPPGWEER_
NEDD4L Ubiquitylation K149 -0.001 0.036 _LK(gl)MAYMPK_
NEDD4L Phosphorylation T302 0.166 0.120 _T(ph)SPQELSEELSR_
NEDD4L Phosphorylation S303 0.166 0.120 _T(ph)SPQELSEELSR_
NEDD4L Phosphorylation S448 0.067 -0.137 _SLS(ph)SPTVTLSAPLEGAK_
NEDD4L Phosphorylation S449 -0.460 -0.435 _SLSS(ph)PTVTLSAPLEGAK_
NEDD4L Ubiquitylation K462 -0.635 -0.011 _SLSSPTVTLSAPLEGAK(gl)DSPVRR_
NEDD4L Ubiquitylation K471 -0.787 _AVK(gl)DTLSNPQSPQPSPYNSPKPQHK_
NEDD4L Ubiquitylation K531 0.704 _LK(gl)FPVHMR_
NEDD4L Ubiquitylation K539 -1.106 -1.175 _SK(gl)TSLNPNDLGPLPPGWEER_
NEDD4L Ubiquitylation K639 0.649 0.864 _IMSVK(gl)RPDVLK_
TRIP12 Phosphorylation S354 -0.672 -0.510 _RSES(ph)PPAELPSLR_
TRIP12 Phosphorylation S990 -1.351 _HLAESESLLTS(ph)PPK_
TRIP12 Phosphorylation S1039 -1.279 -0.356 _DDSLDLS(ph)PQGR_
TRIP12 Ubiquitylation K1049 0.143 0.864 _LSDVLK(gl)R_
TRIP12 Phosphorylation S1064 0.034 -0.036 _YS(ph)PPRDDDKVDNQAK_
TRIP12 Ubiquitylation K1086 -1.660 -1.398 _SPTTTQSPK(gl)SSFLASLNPK_
TRIP12 Ubiquitylation K1096 2.593 _SSFLASLNPK(gl)TWGR_
TRIP12 Ubiquitylation K1473 -0.085 _AQTAPTK(gl)TSPR_
TRIP12 Ubiquitylation K1709 -0.044 -0.188 _GEEVTLSNPK(gl)GSQEGTK_
UBE3A Ubiquitylation K77 0.131 0.538 _ALELYK(gl)INAK_
UBE3A Ubiquitylation K89 -0.782 _LCDPHPSK(gl)K_
UBE3A Ubiquitylation K90 -0.804 _LCDPHPSKK(gl)_
UBE3A Ubiquitylation K112 -0.670 _GAPNNSCSEIK(gl)MNKK_
UBE3A Ubiquitylation K123 0.184 _IDFK(gl)DVTYLTEEK_
UBE3A Phosphorylation S218 3.592 3.254 _IGDSS(ph)QGDNNLQK_
UBE3A Ubiquitylation K315 -0.507 _AMSK(gl)LPLAAQGK_
UBE3A Ubiquitylation K323 -0.547 _LPLAAQGK(gl)LIR_
UBE3A Ubiquitylation K373 1.085 1.052 _NLVNDDDAIVAASK(gl)CLK_
UBE3A Ubiquitylation K552 -0.235 0.125 _LEMIAMENPADLK(gl)K_
UBE3A Ubiquitylation K553 -0.235 0.125 _LEMIAMENPADLK(gl)K_
UBE3A Ubiquitylation K824 0.226 _LK(gl)MIIAK_
UBE3C Ubiquitylation K63 -0.566 _K(gl)QQYSIQR_
UBE3C Ubiquitylation K145 0.477 0.635 _LTCLFQIK(gl)R_
UBE3C Ubiquitylation K565 -1.058 _LAYPETK(gl)PEVR_
UBE3C Ubiquitylation K907 -0.162 _FGGK(gl)DIPVTSANR_
UBR5 Phosphorylation S327 0.474 0.437 _WLDGAS(ph)FDNER_
UBR5 Ubiquitylation K337 -0.172 0.548 _GSTSK(gl)EGEPNLDKK_
UBR5 Ubiquitylation K346 -0.580 _EGEPNLDKK(gl)_
UBR5 Ubiquitylation K423 -1.074 _ATFLGLTNEK(gl)_
UBR5 Ubiquitylation K583 -0.122 _SPESLK(gl)NMEK_
UBR5 Ubiquitylation K587 -0.122 _SPESLK(gl)NMEK_
UBR5 Ubiquitylation K672 -0.561 -0.090 _VLK(gl)VDGAYVAVK_
UBR5 Ubiquitylation K1109 0.878 0.766 _ELLSAK(gl)DAR_
UBR5 Ubiquitylation K1248 0.892 _TLIAGQK(gl)SAR_
UBR5 Ubiquitylation K1351 0.012 0.779 _SMIMFGSQENK(gl)DPLSASSR_
UBR5 Phosphorylation S1549 1.569 0.771 _RIS(ph)QSQPVR_
UBR5 Phosphorylation S2026 -1.786 -1.571 _RS(ph)DSM(ox)TFLGCIPPNPFEVPLAEAIPLADQPHLLQPNAR_
WWP1 Ubiquitylation K66 -0.890 _WK(gl)QPLTVIVTPVSK_
WWP1 Ubiquitylation K328 -0.364 0.487 _SSSAFEAAK(gl)SR_
WWP1 Ubiquitylation K350 0.049 0.396 _VYYVDHVEK(gl)R_
WWP1 Ubiquitylation K446 -1.514 -1.539 _EFDPLGPLPPGWEK(gl)R_
WWP1 Ubiquitylation K478 -1.265 _SQGQLNEK(gl)PLPEGWEMR_
WWP1 Ubiquitylation K513 -0.564 1.593 _TGK(gl)SALDNGPQIAYVR_
WWP1 Ubiquitylation K536 -1.895 1.126 _SSVTK(gl)GGPQIAYER_
WWP1 Ubiquitylation K861 -0.810 0.596 _VGK(gl)ENWLPR_


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